journal article·2020-01-29

Thiol-yne Click Post-Modification for the Synthesis of Chiral Microporous Organic Networks for Chiral Gas Chromatography

Yuan-Yuan Cui, Cheng-Xiong Yang, Xiu-Ping Yan

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Abstract

Microporous organic networks (MONs) have shown great potential in diverse domains recently. However, the application of MONs in chiral separation or catalysis has been largely lagged due to the lack of chiral MONs and the challenge to synthesize chiral MONs. Here we report a facile thiol-yne click strategy to post-synthesize chiral MONs for the first application in chiral gas chromatography. Three chiral MONs with different chiral centers were rationally designed and synthesized to fabricate their capillary columns for gas chromatographic resolution of various chiral compounds with better resolution than three commercial chiral capillary columns. These results show the great potential of the thiol-yne click strategy for constructing newly chiral MONs and their application in chiral separation.
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Research context

OpenAlex topics: Covalent Organic Framework Applications · Metal-Organic Frameworks: Synthesis and Applications · Luminescence and Fluorescent Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

College of Chemistry, Research Center for Analytical Sciences, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Nankai University, Tianjin 300071, China

State Key Laboratory of Food Science and Technology, International Joint Laboratory on Food Safety, Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China

Funding

Natural Science Foundation of Tianjin City · Nankai University · National Natural Science Foundation of China · MOE Key Laboratory of Natural Resources of Changbai Mountain and Functional Molecules, Yanbian University · Tianjin Research Innovation Project of Postgraduate Students

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