journal article·2016-09-21Open access

Surface-Selective Preferential Production of Reactive Oxygen Species on Piezoelectric Ceramics for Bacterial Killing

Guoxin Tan, Shuangying Wang, Ye Zhu, Lei Zhou, Peng Yu, Xiaolan Wang, Tianrui He, Junqi Chen, Chuanbin Mao, Chengyun Ning

Abstract

Reactive oxygen species (ROS) can be used to kill bacterial cells, and thus the selective generation of ROS from material surfaces is an emerging direction in antibacterial material discovery. We found the polarization of piezoelectric ceramic causes the two sides of the disk to become positively and negatively charged, which translate into cathode and anode surfaces in an aqueous solution. Because of the microelectrolysis of water, ROS are preferentially formed on the cathode surface. Consequently, the bacteria are selectively killed on the cathode surface. However, the cell experiment suggested that the level of ROS is safe for normal mammalian cells.
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Research context

OpenAlex topics: Planarian Biology and Electrostimulation · Advanced Sensor and Energy Harvesting Materials · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 51006, China

College of Materials Science and Engineering, South China University of Technology, Guangzhou 510641, China

Department of Chemistry & Biochemistry, Stephenson Life Sciences Research Center, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019, United States

Funding

Ministry of Science and Technology of the People's Republic of China · National Institute of Biomedical Imaging and Bioengineering · Congressionally Directed Medical Research Programs · Division of Civil, Mechanical and Manufacturing Innovation · Oklahoma Center for the Advancement of Science and Technology · National Natural Science Foundation of China · Guangdong Province · Oklahoma Center for Adult Stem Cell Research · Natural Science Foundation of Guangdong Province

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