journal article·2021-09-15Open access

Plasmonic Metasurfaces Based on Pyramidal Nanoholes for High-Efficiency SERS Biosensing

Giovanna Palermo, Massimo Rippa, Ylli Conti, Ambra Vestri, Riccardo Castagna, Giovanna Fusco, Elisabetta Suffredini, Jun Zhou, Joseph Zyss, Antonio De Luca, Lucia Petti

ACS Applied Materials & Interfaces· Volume 13· Issue 36

Abstract

An inverted pyramidal metasurface was designed, fabricated, and studied at the nanoscale level for the development of a label-free pathogen detection on a chip platform that merges nanotechnology and surface-enhanced Raman scattering (SERS). Based on the integration and synergy of these ingredients, a virus immunoassay was proposed as a relevant proof of concept for very sensitive detection of hepatitis A virus, for the first time to our best knowledge, in a very small volume (2 μL), without complex signal amplification, allowing to detect a minimal virus concentration of 13 pg/mL. The proposed work aims to develop a high-flux and high-accuracy surface-enhanced Raman spectroscopy (SERS) nanobiosensor for the detection of pathogens to provide an effective method for early and easy water monitoring, which can be fast and convenient.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Gold and Silver Nanoparticles Synthesis and Applications · Advanced biosensing and bioanalysis techniques · Plasmonic and Surface Plasmon Research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Physics, University of Calabria, Via P. Bucci, 87036 Rende, CS, Italy

CNR NANOTEC—Istituto di Nanotecnologia, UOS Cosenza, 87036 Rende, CS, Italy

Institute of Applied Sciences and Intelligent Systems ”E. Caianiello” CNR, 80078 Pozzuoli, Italy

Department of Food Safety, Nutrition and Veterinary Public Health, Istituto Superiore di Sanitá, 00161 Rome, Italy

Institute of Photonics, Faculty of Science, Ningbo University, 315211 Ningbo, People’s Republic of China

LUMIN Laboratory (CNRS), Institut d’Alembert, Universitè Paris Saclay, 91190 Gif sur Yvette, France

Funding

Ministero dell???Istruzione, dell???Universit?? e della Ricerca · European Regional Development Fund · European Social Fund

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