Tailoring micro/nano-fibers for biomedical applications
Source abstract
Abstract
Nano/micro fibers have evoked much attention of scientists and have been researched as cutting edge and hotspot in the area of fiber science in recent years due to the rapid development of various advanced manufacturing technologies, and the appearance of fascinating and special functions and properties, such as the enhanced mechanical strength, high surface area to volume ratio and special functionalities shown in the surface, triggered by the nano or micro-scale dimensions. In addition, these outstanding and special characteristics of the nano/micro fibers impart fiber-based materials with wide applications, such as environmental engineering, electronic and biomedical fields. This review mainly focuses on the recent development in the various nano/micro fibers fabrication strategies and corresponding applications in the biomedical fields, including tissue engineering scaffolds, drug delivery, wound healing, and biosensors. Moreover, the challenges for the fabrications and applications and future perspectives are presented.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · 3D Printing in Biomedical Research · Graphene and Nanomaterials Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Bioinspired living structural color hydrogels10.1126/scirobotics.aar8580 ↗
2. Bioinspired structural color patch with anisotropic surface adhesion10.1126/sciadv.aax8258 ↗
3. DNA-assembled superconducting 3D nanoscale architectures10.1038/s41467-020-19439-9 ↗
4. Superconducting nanowire fiber mats and the paramagnetic Meissner effect10.1016/j.matpr.2021.10.244 ↗
5. Fiber reinforced GelMA hydrogel to induce the regeneration of corneal stroma10.1038/s41467-020-14887-9 ↗
6. Superelastic hard carbon nanofiber aerogels
7. Bioinspired adhesive and antibacterial microneedles for versatile transdermal drug delivery10.34133/2020/3672120 ↗
8. Nanostructured fibrous membranes with rose spike-like architecture10.1021/acs.nanolett.7b02929 ↗
9. Homeostatic growth of dynamic covalent polymer network toward ultrafast direct soft lithography10.1126/sciadv.abi7360 ↗
10. Programmable self-assembly of three-dimensional nanostructures from 10,000 unique components10.1038/nature24648 ↗
11. 3D bioprinting of tissues and organs10.1038/nbt.2958 ↗
12. General synthesis of complex nanotubes by gradient electrospinning and controlled pyrolysis10.1038/ncomms8402 ↗
13. Conductive cellulose nanofiber enabled thick electrode for compact and flexible energy storage devices10.1002/aenm.201802398 ↗
14. Macroscopic‐scale three‐dimensional carbon nanofiber architectures for electrochemical energy storage devices10.1002/aenm.201700826 ↗
15. Synthesis of chitin nanofiber-coated polymer microparticles via pickering emulsion10.1021/acs.biomac.9b01757 ↗
16. A breathable, biodegradable, antibacterial, and self-powered electronic skin based on all-nanofiber triboelectric nanogenerators10.1126/sciadv.aba9624 ↗
17. Self‐Powered and imperceptible electronic tattoos based on silk protein nanofiber and carbon nanotubes for human–machine interfaces
18. Three-dimensional objects consisting of hierarchically assembled nanofibers with controlled alignments for regenerative medicine10.1021/acs.nanolett.9b00217 ↗
19. Bioinspired supramolecular nanofiber hydrogel through self-assembly of biphenyl-tripeptide for tissue engineering
20. Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering10.1016/j.biomaterials.2020.120225 ↗
21. Recombinant human collagen hydrogels with hierarchically ordered microstructures for corneal stroma regeneration10.1016/j.cej.2021.131012 ↗
22. Deformable high loading liquid metal nanoparticles composites for thermal energy management
23. Gold nanorods and nanohydroxyapatite hybrid hydrogel for preventing bone tumor recurrence via postoperative photothermal therapy and bone regeneration promotion
24. Hybrid nanospheres to overcome hypoxia and intrinsic oxidative resistance for enhanced photodynamic therapy10.1021/acsnano.9b09032 ↗
25. Hydrophobicity-adaptive nanogels for programmed anticancer drug delivery10.1021/acs.nanolett.8b03828 ↗
26. Nanosponges of circulating tumor-derived exosomes for breast cancer metastasis inhibition10.1016/j.biomaterials.2020.119932 ↗
27. 3D bioprinting of cell‐laden hydrogels for improved biological functionality
28. Necklace‐like microfibers with variable knots and perfusable channels fabricated by an oil‐free microfluidic spinning process10.1002/adma.201705082 ↗
29. Large-scale wet-spinning of highly electroconductive MXene fibers10.1038/s41467-020-16671-1 ↗
30. A moss‐inspired electroless gold‐coating strategy toward stretchable fiber conductors by dry spinning10.1002/aelm.201800462 ↗
31. Large-area and adaptable electrospun silicon-based thermoelectric nanomaterials with high energy conversion efficiencies10.1038/s41467-018-07208-8 ↗
32. Near-field electrospinning for three-dimensional stacked nanoarchitectures with high aspect ratios10.1021/acs.nanolett.9b04162 ↗
33. Template-assisted polyelectrolyte encapsulation of nanoparticles into dispersible, hierarchically nanostructured microfibers10.1002/adma.201004048 ↗
34. Multiscale deformations lead to high toughness and circularly polarized emission in helical nacre-like fibres10.1038/ncomms10701 ↗
35. Electrospinning and electrospun nanofibers: methods, materials, and applications10.1021/acs.chemrev.8b00593 ↗
36. Scalable manufacturing and applications of nanofibers10.1016/j.mattod.2019.04.018 ↗
37. Hull · 2000
38. A generalizable strategy for the 3D bioprinting of hydrogels from nonviscous photo‐crosslinkable inks10.1002/adma.201604983 ↗
39. Microfluidic bioprinting of heterogeneous 3D tissue constructs using low‐viscosity bioink10.1002/adma.201503310 ↗
40. High resolution bioprinting of multi-component hydrogels10.1088/1758-5090/ab2aa1 ↗
41. Laser assisted bioprinting of engineered tissue with high cell density and microscale organization10.1016/j.biomaterials.2010.05.055 ↗
42. Desktop‐stereolithography 3D‐printing of a poly (dimethylsiloxane)‐based material with sylgard‐184 properties10.1002/adma.201800001 ↗
43. Current advances and future perspectives in extrusion-based bioprinting10.1016/j.biomaterials.2015.10.076 ↗
44. Organ printing: computer-aided jet-based 3D tissue engineering10.1016/S0167-7799(03)00033-7 ↗
45. Engineered tissue scaffolds with variational porous architecture10.1115/1.4002933 ↗
46. Current trends in the design of scaffolds for computer-aided tissue engineering10.1016/j.actbio.2013.10.024 ↗
47. Recent strategies in extrusion-based three-dimensional cell printing toward organ biofabrication10.1021/acsbiomaterials.8b00691 ↗
48. Advances in extrusion 3D bioprinting: a focus on multicomponent hydrogel‐based bioinks10.1002/adhm.201901648 ↗
49. Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting10.1089/ten.tea.2009.0798 ↗
50. Effects of silica and zinc oxide doping on mechanical and biological properties of 3D printed tricalcium phosphate tissue engineering scaffolds10.1016/j.dental.2011.09.010 ↗
51. Aqueous two‐phase emulsion bioink‐enabled 3D bioprinting of porous hydrogels
52. Three-dimensional bioassembly tool for generating viable tissue-engineered constructs10.1089/ten.2004.10.1566 ↗
53. Thermally-controlled extrusion-based bioprinting of collagen10.1007/s10856-019-6258-2 ↗
54. Optimization of collagen type I-hyaluronan hybrid bioink for 3D bioprinted liver microenvironments10.1088/1758-5090/aae543 ↗
55. Collagen and chitosan blends for 3D bioprinting: a rheological and printability approach10.1016/j.polymertesting.2019.106297 ↗
56. Bioprinted amniotic fluid‐derived stem cells accelerate healing of large skin wounds10.5966/sctm.2012-0088 ↗
57. Engineering alginate as bioink for bioprinting10.1016/j.actbio.2014.06.034 ↗
58. 3D B ioprinting of complex channels—effects of material, orientation, geometry, and cell embedding10.1002/jbm.a.35393 ↗
59. 3D printing of biomimetic multi-layered GelMA/nHA scaffold for osteochondral defect repair10.1016/j.matdes.2019.107708 ↗
60. 3D bioprinting of carbohydrazide-modified gelatin into microparticle-suspended oxidized alginate for the fabrication of complex-shaped tissue constructs10.1021/acsami.0c05096 ↗
61. Coaxial extrusion bioprinting of 3D microfibrous constructs with cell-favorable gelatin methacryloyl microenvironments10.1088/1758-5090/aa9d44 ↗
62. 3D bioprinting of liver-mimetic construct with alginate/cellulose nanocrystal hybrid bioink10.1016/j.bprint.2017.12.001 ↗
63. 3D Bioprinting of functional islets of langerhans in an alginate/methylcellulose hydrogel blend
64. Emerging droplet microfluidics10.1021/acs.chemrev.6b00848 ↗
65. Microfluidic spinning of cell‐responsive grooved microfibers10.1002/adfm.201404531 ↗
66. Microfluidic production of multiple emulsions and functional microcapsules10.1039/C6LC00809G ↗
67. Microfluidic fabrication of complex-shaped microfibers by liquid template-aided multiphase microflow10.1039/c0lc00711k ↗
68. Microfluidic synthesis of chemically and physically anisotropic hydrogel microfibers for guided cell growth and networking10.1039/c2sm07263g ↗
69. Template-based fabrication of spatially organized 3D bioactive constructs using magnetic low-concentration gelation methacrylate (GelMA) microfibers10.1039/C9SM01945F ↗
70. Simple spinning of heterogeneous hollow microfibers on chip10.1002/adma.201601504 ↗
71. Micro/nanometer‐scale fiber with highly ordered structures by mimicking the spinning process of silkworm10.1002/adma.201300837 ↗
72. Bioinspired helical micromotors as dynamic cell microcarriers10.1021/acsami.0c01264 ↗
73. Bio-inspired multicomponent carbon nanotube microfibers from microfluidics for supercapacitor10.1016/j.cej.2020.125517 ↗
74. Bioinspired hydrogel microfibres colour-encoded with colloidal crystals10.1039/C9MH00528E ↗
75. Microfluidic spinning of micro-and nano-scale fibers for tissue engineering10.1039/C3LC51414E ↗
76. Microfluidic fabrication of multiaxial microvessels via hydrodynamic shaping10.1039/C4RA03667K ↗
77. Hydrodynamic spinning of hydrogel fibers10.1016/j.biomaterials.2009.10.002 ↗
78. Microfluidic controlled mass‐transfer and buckling for easy fabrication of polymeric helical fibers10.1002/marc.201500632 ↗
79. Design of capillary microfluidics for spinning cell-laden microfibers10.1038/s41596-018-0051-4 ↗
80. Microfluidic fabrication of cell adhesive chitosan microtubes10.1007/s10544-013-9746-z ↗
81. Continuous jetting of alginate microfiber in atmosphere based on a microfluidic chip10.3390/mi8010008 ↗
82. Microfluidic wet-spinning of alginate microfibers: a theoretical analysis of fiber formation10.1039/c2sm25552a ↗
83. Microfluidic spinning of flat alginate fibers with grooves for cell‐aligning scaffolds10.1002/adma.201201232 ↗
84. Digitally tunable physicochemical coding of material composition and topography in continuous microfibres10.1038/nmat3108 ↗
85. Microfluidic synthesis of pure chitosan microfibers for bio-artificial liver chip10.1039/b924987g ↗
86. Microfluidic chip-based fabrication of PLGA microfiber scaffolds for tissue engineering10.1021/la800253b ↗
87. The microfluidic synthesis of composite hollow microfibers for k+-responsive controlled release based on a host–guest system10.1039/C6TB00333H ↗
88. A simple sheath-flow microfluidic device for micro/nanomanufacturing: fabrication of hydrodynamically shaped polymer fibers10.1039/b910581f ↗
89. A microfluidic approach to synthesizing high-performance microfibers with tunable anhydrous proton conductivity10.1039/c3lc50862e ↗
90. Mechanical and physical properties of poly (vinyl alcohol) microfibers fabricated by a microfluidic approach10.1039/C6RA09519D ↗
91. Tunable silk: using microfluidics to fabricate silk fibers with controllable properties10.1021/bm1014624 ↗
92. Controllable preparation of microscale tubes with multiphase co-laminar flow in a double co-axial microdevice10.1039/b913247c ↗
93. Hydrodynamic microfabrication via “on the fly” photopolymerization of microscale fibers and tubes10.1039/B411249K ↗
94. “On the fly” continuous generation of alginate fibers using a microfluidic device10.1021/la700818q ↗
95. Strontium ion substituted alginate‐based hydrogel fibers and its coordination binding model10.1002/app.48571 ↗
96. Microfluidic control of the internal morphology in nanofiber‐based macroscopic cables10.1002/ange.201202078 ↗
97. Microfluidic strategies for design and assembly of microfibers and nanofibers with tissue engineering and regenerative medicine applications10.1002/adhm.201400144 ↗
98. Enhanced skeletal muscle formation on microfluidic spun gelatin methacryloyl (GelMA) fibres using surface patterning and agrin treatment10.1002/term.2738 ↗
99. Bioinspired microfibers with embedded perfusable helical channels10.1002/adma.201701664 ↗
100. Formation of helical alginate microfibers using different G/M ratios of sodium alginate based on microfluidics10.1016/j.snb.2019.127069 ↗