DataVXACS Applied Materials & InterfacesPaper
journal article·2015-12-30

Highly Photoluminescent Nitrogen-Doped Carbon Nanodots and Their Protective Effects against Oxidative Stress on Cells

Zi-Qiang Xu, Jia-Yi Lan, Jian-Cheng Jin, Ping Dong, Feng-Lei Jiang, Yi Liu

ACS Applied Materials & Interfaces· Volume 7· Issue 51
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Source abstract

Abstract

Highly photoluminescent (PL) (quantum yield = 54%) nitrogen doped carbon nanodots (C-dots) have been prepared through one-step carbonizing citric acid and tris(hydroxymethyl)aminomethane and using oleic acid as solvent. The synthesized C-dots are monodisperse with narrow size distribution (average 1.7 nm). The PL properties of C-dots are pH dependent, and hence, using C-dots as sophisticated pH sensor to detect pH values between 7 and 9 can be expected. In addition, the PL intensity of C-dots remains stable under high ionic strength. The C-dots can protect cells from oxidative stress, which shows potential to expand the biological application of C-dots, especially in medical treatment. The protective mechanism is associated with intracellular reactive oxygen species elimination and the intracellular superoxide dismutase production.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Carbon and Quantum Dots Applications · Advanced Nanomaterials in Catalysis · Nanocluster Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory of Virology & Key Laboratory of Analytical Chemistry for Biology and Medicine (MOE), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, P. R. China

Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials, Ministry-of-Education Key Laboratory for the Green Preparation andApplication of Functional Materials, Hubei Province Key Laboratory of Industrial Biotechnology, Hubei Key Laboratory of Polymer Materials, Faculty of Materials Science & Engineering, Hubei University, Wuhan 430062, P. R. China

Funding

Ministry of Education of the People's Republic of China · National Natural Science Foundation of China

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