DataVXACS Applied Materials & InterfacesPaper
journal article·2016-01-13Open access

Enhanced Analytical Performance of Paper Microfluidic Devices by Using Fe3O4 Nanoparticles, MWCNT, and Graphene Oxide

Federico Figueredo, Paulo T. Garcia, Eduardo Cortón, Wendell K. T. Coltro

ACS Applied Materials & Interfaces· Volume 8· Issue 1
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Source abstract

Abstract

Spheres, tubes, and planar-shaped nanomaterials as Fe3O4 nanoparticles (MNPs), multiwalled carbon nanotubes (MWCNT), and graphene oxide (GO) were used for the first time to treat microfluidic paper-based analytical devices (μPADs) and create a biocompatible layer with high catalytic surface. Once glucose measurements are critical for diabetes or glycosuria detection and monitoring, the analytical performance of the proposed devices was studied by using bienzymatic colorimetric detection of this carbohydrate. The limit of detection values achieved for glucose with μPADs treated with MNPs, MWCNT, and GO were 43, 62, and 18 μM, respectively. The paper surface modification solves problems associated with the lack of homogeneity on color measurements that compromise the sensitivity and detectability levels in clinical diagnosis.
Source: openalex_inverted_index · Quality: baseline

Research context

NanomaterialsBiomaterialsCatalysis & surfaces

OpenAlex topics: Biosensors and Analytical Detection · Advanced biosensing and bioanalysis techniques · Electrochemical sensors and biosensors

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Instituto de Química, Universidade Federal de Goiás, Goiânia, GO 74690-900, Brazil

Laboratorio de Biosensores y Bioanálisis (LABB), Departamento de Química Biológica e IQUIBICEN−CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires (UBA), Pabellón 2, Ciudad Universitaria, Ciudad Autónoma de Buenos Aires, Argentina

Funding

Consejo Nacional de Investigaciones Científicas y Técnicas · Fundação de Amparo à Pesquisa do Estado de Goiás · Conselho Nacional de Desenvolvimento Científico e Tecnológico · Instituto Nacional de Ciência e Tecnologia em Bioanalítica

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