High-Throughput Generation of Emulsions and Microgels in Parallelized Microfluidic Drop-Makers Prepared by Rapid Prototyping
Source abstract
Abstract
We describe the preparation of rapid prototyped parallelized microfluidic drop-maker devices. The manufacturing technique facilitates stacking of the drop-makers vertically on top of each other allowing for a reduced footprint and minimized dead-volume through efficient design of the distribution channels. We showcase the potential of the additive manufacturing technique for microfluidics and the performance of the parallelized device by producing large amounts of microgels with a diameter of ca. 500 μm, a size that is inaccessible using traditional synthetic approaches.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Innovative Microfluidic and Catalytic Techniques Innovation · 3D Printing in Biomedical Research · Electrowetting and Microfluidic Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
DWI−Leibniz Institute for Interactive Materials, Forckenbeckstrasse 50, 52074 Aachen, Germany
Chemical Process Engineering AVT.CVT, RWTH Aachen University, Turmstrasse 46, 52064 Aachen, Germany
Funding
Alexander von Humboldt-Stiftung · Deutsche Forschungsgemeinschaft
References (30)
Show source-provided references
1. Chern C. S. · Prog. Polym. Sci. · 2006 · 31 · 44310.1016/j.progpolymsci.2006.02.001 ↗
2. Kawaguchi S. · Adv. Polym. Sci. · 2005 · 175 · 29910.1007/b100118 ↗
3. Tumarkin E. · Chem. Soc. Rev. · 2009 · 38 · 216110.1039/b809915b ↗
4. Wang W. · Acc. Chem. Res. · 2014 · 47 · 37310.1021/ar4001263 ↗
5. Kuehne A. J. C. · Chem. Commun. · 2011 · 47 · 1237910.1039/c1cc14251h ↗
6. Romanowski M. B. · Lab Chip · 2012 · 12 · 80210.1039/c2lc21033a ↗
7. Kim S.-H. · Microfluid. Nanofluidics · 2012 · 14 · 50910.1007/s10404-012-1069-5 ↗
8. Muluneh M. · Lab Chip · 2013 · 13 · 475010.1039/c3lc50979f ↗
9. Li W. · Lab Chip · 2009 · 9 · 271510.1039/b906626h ↗
10. Nisisako T. · Lab Chip · 2012 · 12 · 342610.1039/c2lc40245a ↗
11. Bardin D. · Biomicrofluidics · 2013 · 7 · 03411210.1063/1.4811276 ↗
12. Conchouso D. · Lab Chip · 2014 · 14 · 301110.1039/C4LC00379A ↗
13. Holtze C. · J. Phys. D: Appl. Phys. · 2013 · 46 · 11400810.1088/0022-3727/46/11/114008 ↗
14. Au A. K. · Lab Chip · 2014 · 14 · 129410.1039/C3LC51360B ↗
15. King P. H. · Lab Chip · 2014 · 14 · 72210.1039/C3LC51072G ↗
16. Comina G. · Lab Chip · 2014 · 14 · 42410.1039/C3LC50956G ↗
17. McDonald J. C. · Anal. Chem. · 2002 · 74 · 153710.1021/ac010938q ↗
18. Capel A. J. · Lab Chip · 2013 · 13 · 458310.1039/c3lc50844g ↗
19. Erkal J. L. · Lab Chip · 2014 · 14 · 202310.1039/C4LC00171K ↗
20. Symes M. D. · Nat. Chem. · 2012 · 4 · 34910.1038/nchem.1313 ↗
21. Waldbaur A. · Anal. Methods · 2011 · 3 · 268110.1039/c1ay05253e ↗
22. Kitson P. J. · Lab Chip · 2012 · 12 · 326710.1039/c2lc40761b ↗
23. Donvito L. · J. Micromech. Microeng. · 2015 · 25 · 03501310.1088/0960-1317/25/3/035013 ↗
24. Yuen P. K. · Lab Chip · 2009 · 9 · 330310.1039/b912295h ↗
25. Abrahamse A. J. · J. Membr. Sci. · 2002 · 204 · 12510.1016/S0376-7388(02)00028-5 ↗
26. Melchels F. P. · Biomaterials · 2010 · 31 · 612110.1016/j.biomaterials.2010.04.050 ↗
27. Femmer T. · Lab Chip · 2014 · 14 · 261010.1039/c4lc00320a ↗
28. Femmer T. · J. Membr. Sci. · 2015 · 478 · 1210.1016/j.memsci.2014.12.040 ↗
29. Torres-Rendon J. G. · Adv. Mater. · 2015 · 27 · 298910.1002/adma.201405873 ↗
30. Seiffert S. · Soft Matter · 2010 · 6 · 318410.1039/c0sm00071j ↗