Chitosan Sponge/Cu–WO3–x Composite for Photodynamic Therapy of Wound Infection
Source abstract
Abstract
One of the potential treatments for bacterial wound infections is photodynamic therapy. WO 3– x semiconductor materials can generate reactive oxygen species when exposed to light, which can inactivate bacteria. In this work, we improved their photocatalytic performance by doping WO 3– x with Cu. The wound dressing was prepared by loading Cu–WO 3– x into a highly biocompatible chitosan sponge. The composite sponge dressing showed significant inactivation of Escherichia coli and Staphylococcus aureus, and in vitro toxicity assays on L929 cells demonstrated the biosafety of the dressing. Through in vivo wound healing trials, composite sponge dressings have been shown to accelerate wound healing, and this composite chitosan sponge can be possibly used for photodynamic therapy of bacterial wound infections.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Nanocomposite Films for Food Packaging · Advanced Sensor and Energy Harvesting Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Guangzhou Institute of Chemistry, Chinese Academy of Sciences, 510650 Guangzhou, P. R. China
University of Chinese Academy of Sciences, 100000 Beijing, P. R. China
Guizhou Police College, Guizhou 550005, China
CAS Testing Technical Services (Guangzhou) Co. Ltd., 510650 Guangzhou, P. R. China
CAS Engineering Laboratory for Special Fine Chemicals, Chinese Academy of Sciences, Guangzhou 510650, P. R. China
Guangdong Provincial Key Laboratory of Organic Polymer Materials for Electronics, Guangzhou 510650, P. R. China
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