Comparative Hydrodynamic Analysis and Optimization of Gyroid and Diamond Scaffolds with Functionally Graded Porosity
Source abstract
Abstract
This study presents a numerical investigation into the hydrodynamic and biomechanical performance of bone-repair scaffolds based on Triply Periodic Minimal Surfaces (TPMSs). Focusing on Gyroid and Diamond architectures, scaffolds with uniform (40–70%) and functionally graded porosities were developed. Computational Fluid Dynamics (CFD) simulations were employed to evaluate permeability, pressure drop, and Wall Shear Stress (WSS) distributions. Results indicate distinct topological advantages: the Gyroid structure demonstrates superior permeability and uniform WSS distribution due to its isotropic fluid channels, whereas the Diamond structure maintains better flow velocity stability. Crucially, the introduction of a porosity gradient (40–60%) successfully mitigates localized pressure surges and optimizes the bioactive WSS window for cell differentiation. Notably, increasing porosity to 70% in Gyroid scaffolds yielded a 277% enhancement in permeability. These findings establish a theoretical basis for designing functionally graded TPMS scaffolds that balance fluid transport efficiency with a favorable cellular microenvironment.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Calcium Carbonate Crystallization and Inhibition · Pickering emulsions and particle stabilization
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
School of Mechanical and Automotive Engineering, Shanghai University of Engineering Science, Shanghai 201620, China
School of Energy and Power Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
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