Encapsulation of Snail Slime in Metal–Organic Framework ZIF-8
Source abstract
Abstract
The literature consistently identifies Zeolitic Imidazolate Framework-8 (ZIF-8) as an excellent material for on-demand drug delivery. Its appeal results from its superior loading capacity, inherent stability within physiological environments, and the ability to fine-tune its drug release kinetics. In this work, we investigated the encapsulation of snail slime extracted from Cornu aspersum mucus into ZIF-8. PXRD, SEM microscopy, ATR-FTIR spectroscopy, and fluorescence microscopy were used for a detailed characterization of the nanoparticles. The antibacterial potential of the ZIF-8-based biocomposite was assayed in vitro against Staphylococcus epidermidis. Overall, the results indicate that encapsulating the snail slime within ZIF-8 enhances its antibacterial activity, yielding a potent antimicrobial material.
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Research context
OpenAlex topics: Metal-Organic Frameworks: Synthesis and Applications · Calcium Carbonate Crystallization and Inhibition · Microbial Applications in Construction Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Industrial Chemistry “Toso Montanari”, University of Bologna, Via Piero Gobetti 85, 40129 Bologna, Italy
Center for Industrial Research-Advanced Applications in Mechanical Engineering and Materials Technology (CIRI-MAM), University of Bologna, Viale del Risorgimento 2, 40136 Bologna, Italy
Department of Pharmacy and Biotechnology, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy
Department of Chemistry “G. Ciamician”, University of Bologna, Via Piero Gobetti 85, 40129 Bologna, Italy
Center for Industrial Research-Fonti Rinnovabili, Ambiente, Mare e Energia (CIRI-FRAME), University of Bologna, Viale del Risorgimento 2, 40136 Bologna, Italy
Health Sciences and Technologies—Interdepartmental Center for Industrial Research (HST–ICIR), Alma Mater Studiorum—University of Bologna, Ozzano dell’Emilia, 40064 Bologna, Italy
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