journal article·2025-04-27Open access

Functional Biomaterials: Scaffolds for Innovative Treatments

Cristian Scheau, Andreea Cristiana Didilescu, Constantin Caruntu

Abstract

Numerous therapies for a multitude of pathologies have reached their limits [...].
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Bone Tissue Engineering Materials · Additive Manufacturing and 3D Printing Technologies

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Physiology, The “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

Department of Radiology and Medical Imaging, “Foisor” Clinical Hospital of Orthopaedics, Traumatology and Osteoarticular TB, 021382 Bucharest, Romania

Department of Embryology and Microbiology, Faculty of Dentistry, The “Carol Davila” University of Medicine and Pharmacy, 050474 Bucharest, Romania

Department of Dermatology, “Prof. N.C. Paulescu” National Institute of Diabetes, Nutrition and Metabolic Diseases, 011233 Bucharest, Romania

References (33)

Show source-provided references
1. Jammalamadaka, U., and Tappa, K. (2018). Recent Advances in Biomaterials for 3D Printing and Tissue Engineering. J. Funct. Biomater., 9.10.3390/jfb9010022 ↗
2. Yon, C.J., Choi, B.C., Lee, J.M., and Lee, S.W. (2025). Personalized 3D-Printed Prostheses for Bone Defect Reconstruction After Tumor Resection in the Foot and Ankle. J. Funct. Biomater., 16.10.3390/jfb16020062 ↗
3. Moving Boundaries for Improving Organ Transplant Availability
4. Tumor biomarkers for diagnosis, prognosis and targeted therapy10.1038/s41392-024-01823-2 ↗
5. Scheau, C., Didilescu, A.C., and Caruntu, C. (2024). Innovative Biomaterials: The Cornerstone of Next-Generation Medical Solutions. J. Funct. Biomater., 15.10.3390/jfb15080218 ↗
6. Todd, E.A., Mirsky, N.A., Silva, B.L.G., Shinde, A.R., Arakelians, A.R.L., Nayak, V.V., Marcantonio, R.A.C., Gupta, N., Witek, L., and Coelho, P.G. (2024). Functional Scaffolds for Bone Tissue Regeneration: A Comprehensive Review of Materials, Methods, and Future Directions. J. Funct. Biomater., 15.10.3390/jfb15100280 ↗
7. Timofticiuc, I.-A., Călinescu, O., Iftime, A., Dragosloveanu, S., Caruntu, A., Scheau, A.-E., Badarau, I.A., Didilescu, A.C., Caruntu, C., and Scheau, C. (2023). Biomaterials adapted to VAT photopolymerization in 3D printing: Characteristics and medical applications. J. Funct. Biomater., 15.10.3390/jfb15010007 ↗
8. Sousa, A.C., Alvites, R., Lopes, B., Sousa, P., Moreira, A., Coelho, A., Santos, J.D., Atayde, L., Alves, N., and Maurício, A.C. (2025). Three-Dimensional Printing/Bioprinting and Cellular Therapies for Regenerative Medicine: Current Advances. J. Funct. Biomater., 16.10.3390/jfb16010028 ↗
9. Timofticiuc, I.-A., Dragosloveanu, S., Caruntu, A., Scheau, A.-E., Badarau, I.A., Garofil, N.D., Didilescu, A.C., Caruntu, C., and Scheau, C. (2024). 3D Bioprinting in Limb Salvage Surgery. J. Funct. Biomater., 15.10.3390/jfb15120383 ↗
10. Choi, J., Lee, E.J., Jang, W.B., and Kwon, S.M. (2023). Development of Biocompatible 3D-Printed Artificial Blood Vessels through Multidimensional Approaches. J. Funct. Biomater., 14.10.3390/jfb14100497 ↗
11. Dragosloveanu, S., Capitanu, B.S., Moise, M.N., Vulpe, D.E., Josanu, R., Gherghe, M.E., Preda, E.M., Cergan, R., and Scheau, C. (2025). Restoring Hip Symmetry and Its Impact on Outcomes: A Case Series on Megaprosthesis Use in Non-Oncological Patients with Complications After Total Hip Arthroplasty. Symmetry, 17.10.3390/sym17030322 ↗
12. Wong, S.K., Yee, M.M.F., Chin, K.Y., and Ima-Nirwana, S. (2023). A Review of the Application of Natural and Synthetic Scaffolds in Bone Regeneration. J. Funct. Biomater., 14.10.3390/jfb14050286 ↗
13. Buranawat, B., Shaalan, A., Garna, D.F., and Di Silvio, L. (2025). Development of Prevascularized Synthetic Block Graft for Maxillofacial Reconstruction. J. Funct. Biomater., 16.10.3390/jfb16010018 ↗
14. Pudełko-Prażuch, I., Balasubramanian, M., Ganesan, S.M., Marecik, S., Walczak, K., Pielichowska, K., Chatterjee, S., Kandaswamy, R., and Pamuła, E. (2024). Characterization and In Vitro Evaluation of Porous Polymer-Blended Scaffolds Functionalized with Tricalcium Phosphate. J. Funct. Biomater., 15.10.3390/jfb15030057 ↗
15. Durán Hernández, O., Baumer, V., Marrero, G., Karumanchi, S., and Prawel, D. (2025). Fabrication and Characterization of Highly Porous Gyroid Scaffolds Composed of Deproteinized Bone Mineral. J. Funct. Biomater., 16.10.3390/jfb16040119 ↗
16. Cecuda-Adamczewska, V., Romanik-Chruścielewska, A., Kosowska, K., Sokołowska, I., Łukasiewicz, N., Korycka, P., Florys-Jankowska, K., Zakrzewska, A., Wszoła, M., and Klak, M. (2024). Elasticity Modification of Biomaterials Used in 3D Printing with an Elastin-Silk-like Recombinant Protein. J. Funct. Biomater., 15.10.3390/jfb15060141 ↗
17. Nieto, S., Gantiva-Díaz, M., Hoyos, M.A., Montoya, Y., Cruz, J.C., and Cifuentes-De la Portilla, C. (2024). Advancing Adult-Acquired Flatfoot Deformity Treatment: Enhanced Biomechanical Support Through Graphene Oxide-Integrated Bioengineered Grafts Tested In Silico. J. Funct. Biomater., 15.10.3390/jfb15110335 ↗
18. Impact of peri-implant soft tissue characteristics on health and esthetics10.1111/jerd.13003 ↗
19. Tabanella, G., and Viale, M. (2024). Porcine Cross-Linked Collagen Matrix for Peri-Implant Vertical Soft Tissue Augmentation: A Randomized Prospective Observational Study. J. Funct. Biomater., 15.10.3390/jfb15090261 ↗
20. Duarte, N.D., Mulinari-Santos, G., Batista, F.R.d.S., Gomes, M.B., Monteiro, N.G., Silva, A.C.E.d., Gruber, R., Lisboa-Filho, P.N., Gomes-Ferreira, P.H.S., and Okamoto, R. (2024). Sonification of Deproteinized Bovine Bone Functionalized with Genistein Enhances Bone Repair in Peri-Implant Bone Defects in Ovariectomized Rats. J. Funct. Biomater., 15.10.3390/jfb15110328 ↗
21. Skrajnowska, D., Bielecki, W., Szterk, A., Ofiara, K., and Bobrowska-Korczak, B. (2024). Genistein Supplementation and Bone Health in Breast Cancer in Rats. Nutrients, 16.10.3390/nu16060912 ↗
22. 3D printing of drug delivery systems enhanced with micro/nano-technology10.1016/j.addr.2024.115479 ↗
23. Silica nanoparticles (SiNPs) derived from melon seed husk ameliorate Ni/Al mixture-mediated cognitive impairment in rats10.25122/jml-2024-0019 ↗
24. Boyuklieva, R., Katsarov, P., Zagorchev, P., Abarova, S., Hristozova, A., and Pilicheva, B. (2024). Development of Nanocomposite Microspheres for Nasal Administration of Deferiprone in Neurodegenerative Disorders. J. Funct. Biomater., 15.10.3390/jfb15110329 ↗
25. Kaupbayeva, B., Tsoy, A., Safarova, Y., Nurmagambetova, A., Murata, H., Matyjaszewski, K., and Askarova, S. (2024). Unlocking Genome Editing: Advances and Obstacles in CRISPR/Cas Delivery Technologies. J. Funct. Biomater., 15.10.3390/jfb15110324 ↗
26. Shumega, A.R., Pavlov, Y.I., Chirinskaite, A.V., Rubel, A.A., Inge-Vechtomov, S.G., and Stepchenkova, E.I. (2024). CRISPR/Cas9 as a Mutagenic Factor. Int. J. Mol. Sci., 25.10.3390/ijms25020823 ↗
27. Melchor-Moncada, J.J., Vasquez-Giraldo, S., Zuluaga-Vélez, A., Orozco, L.M., Veloza, L.A., and Sepúlveda-Arias, J.C. (2024). Bioconjugation of Serratiopeptidase with Titanium Oxide Nanoparticles: Improving Stability and Antibacterial Properties. J. Funct. Biomater., 15.10.3390/jfb15100300 ↗
28. Nair, S.R., and C, S.D. (2022). Serratiopeptidase: An integrated View of Multifaceted Therapeutic Enzyme. Biomolecules, 12.10.3390/biom12101468 ↗
29. Preclinical study analysis of massive magnesium alloy graft for calcaneal fractures10.3892/etm.2021.10163 ↗
30. Saqib, M., Kremmer, K., Opitz, J., Schneider, M., and Beshchasna, N. (2024). Evaluation of the Degradation Properties of Plasma Electrolytically Oxidized Mg Alloy AZ31 Using Fluid Dynamic Accelerated Tests for Biodegradable Implants. J. Funct. Biomater., 15.10.3390/jfb15120366 ↗
31. Knight, Z., Ruiz, A., and Elies, J. (2025). Piezoelectric Nanomaterials for Cancer Therapy: Current Research and Future Perspectives on Glioblastoma. J. Funct. Biomater., 16.10.3390/jfb16040114 ↗
32. Valerius, A.R., Webb, L.M., Thomsen, A., Lehrer, E.J., Breen, W.G., Campian, J.L., Riviere-Cazaux, C., Burns, T.C., and Sener, U. (2024). Review of Novel Surgical, Radiation, and Systemic Therapies and Clinical Trials in Glioblastoma. Int. J. Mol. Sci., 25.10.3390/ijms251910570 ↗
33. Evangelista, A., Scocozza, F., Conti, M., Auricchio, F., Conti, B., Dorati, R., Genta, I., Benazzo, M., and Pisani, S. (2025). Exploring Mechanical Features of 3D Head and Neck Cancer Models. J. Funct. Biomater., 16.10.3390/jfb16030074 ↗