journal article·2024-09-16Open access

Impact of Calcium Lactate Pretreatment on Enamel Fluoride Uptake: A Comparative In Vitro Study of Different Fluoride Types and Concentrations

Fjolla Kullashi Spahija, Ivana Sutej, Kresimir Basic, Kreshnik Spahija, Kristina Peros

Abstract

(1) Background: This study aimed to establish the effect of calcium lactate enamel pretreatment related to different fluoride types and concentrations on the enamel uptake of alkali-soluble fluorides. (2) Materials: In a blind and randomized in vitro study, a total of 60 teeth are used. The first 30 teeth were cut and randomly allocated into one of the following treatments: (A) calcium lactate pretreatment followed by three different fluoride solutions; (B) the “Fluoride only” group, with slabs treated with three different fluoride solutions; (C) the “Calcium only” group, with slabs treated with calcium lactate solution; (D) slabs treated with deionized water (negative control group). The next 30 teeth underwent all the above described group procedures but were treated with lower fluoride concentrations. Fluoride was extracted from enamel using 1 M KOH solution and analyzed using a fluoride ion-specific electrode. (3) Results: The findings revealed that slabs treated with NaF following calcium lactate pretreatment exhibited significantly greater enamel uptake of alkali-soluble fluoride compared to other substrates. This significant effect was not observed at lower fluoride concentrations. (4) Conclusion: The study demonstrates that pretreatment with calcium lactate followed by treatment with NaF at 226 ppm F significantly enhances the uptake of alkali-soluble fluoride in enamel compared to other fluoride types.
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Research context

OpenAlex topics: Dental Health and Care Utilization · Fluoride Effects and Removal · Dental Erosion and Treatment

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmacology, School of Dental Medicine, 10000 Zagreb, Croatia

Dental Policlinic Center, 30000 Peja, Kosovo

Funding

Croatian Ministry of Science, Educattion and Youth · University of Zagreb School of Dental Medicine

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