The preparation and property of N-halamine modified chitosan/PVA antibacterial composite film

Chitosan has attracted researchers' wide attention due to its excellent properties such as biodegradability,biocompatibility and antibacterial property. Based on our preliminary studies,composite films in different proportions were prepared by physically mixing N-halamine modified chitosan( CTS-GH) and polyvinyl alcohol( PVA) to improve practical application of composite films. The miscibility of the mixed solution was examined by atomic force microscopy(AFM). The miscibility of the composite films was characterized by scanning electron microscopy(SEM),differential scanning calorimetry( DSC),X-ray diffraction( XRD). The antimicrobial property of the chlorinated composite film was evaluated. The results showed that the miscibility of CTS-GH / PVA composite film is perfect with the exception of CTSGH / PVA = 10 /90. After the chlorination treatment,the composite film with chlorine content of 0. 86 × 1018 atoms / cm2(CTS-GH/PVA = 20 /80) can kill 98. 92% Staphylococcus aureus and 100% Escherichia coli within 5 min,and 100%Staphylococcus aureus within 60 min.