Study on the antibacterial activity of nanometer SiO_x which was covalently bonded with quaternary ammonium salts with γ-chloropropyl trimethoxy siloxane as active agents

The long-chain high-molecular-weight polyethylenimine(PEI) was grafted on the surface of nanometer SiOx,then the PEI was alkylated to high-molecular-weight quaternary ammonium salts by the alkyl halide.It was proved that this kind of nanometer SiOx had antibacterial activity against the Gram-positive bacterial,Gram-negative bacterial,yeast and mould by the results of antibacterial activity test.The critical antibacterial concentration to the bacterial was 1.0mg/ml.The heat treatment test and washing experiments proved that the heat resistance and stability of the nanometer SiOx was good.