Study on genetic toxicity of the TiNi shape memory alloy in artificial esophagus

The genetic toxicity of TiNi SMA alloy in the artifical esophagus were investigated in the paper.With an accelerated degradation method the variation of the human body embedding TiNi alloy as implant for long time was simulated.With the miniature nucleus tests with RBC of mouse marrow the genetic toxicity of TiNi SMA alloy in the artifical esophagus was evaluated.The evaluasion results show that the genetic toxicity of TiNi SMA alloy appears negative.The TiNi Shape Memory Alloy with good biologic compatibility is a better material as the carcass in the artificial esophagus.