Study on the hydrophilicity of porcine acellular dermal matrix crosslinked by glycerol polyglycidyl ether

Porcine acellular dermal matrix(pADM) was crosslinked by serial dosage 0,5%,10%,20%,40%,100%(wt) of glycerol polyglycidyl ether(GPE).The properties of them were characterized with Ts,hygroscopicity,rate of absorbed water,water retentivity,contact angel,FT-IR,XPS and SEM before and after crosslinked.With the increase of GPE concentration,Ts of GPE-pADM was enhanced obviously.The holes of GPE-pADM tended to shrink after crosslinked from the SEM image of the material surface,and it resulted in the fall of the rate of absorbed water and hygroscopicity.Improvement of surface hydrophilicity was proved by the decline of contact angle in the surface of GEP-pADM.The added polar bond,aliphatic ether bond and C—O bond,were discovered by the shape(about 1083cm-1) change of IR spectroscopy curves and the increase of content of oxygen were observed by XPS,consistent with the principle of GPE crosslink reaction,which was the result of increasement of combined water and hydrophilicity.These proved that hydrophilicity of pADM was increased after crosslinked by GPE.