The preparation and characterization of CMCS-coated VE liposome

In the present work,we report the synthesis of carboxymethyl chitosan(CMCS) and the preparation of CMCS-coated VE liposome.TEM images of the CMCS-coated VE liposome showed that the particles were spherical and well separated.The influences of the CMCS concentration were not obvious to the zeta potential and average particle size of the CMCS-coated VE liposome.The conserving rate of the liposome increased and sedimentation volume rate decreased with the increasing CMCS concentration.The results indicated that the coating of the CMCS enhanced the storage stability of the VE liposome effectively.