journal article·2025-06Open access

Multifunctional DNA‐Metal Nanohybrids Derived From DNA‐MgPPi Microhybrids by Rolling Circle Amplification (Small Methods 6/2025)

Young Min Kim, Keonwook Nam, Hee Yeon Kim, Kyungjik Yang, Byeong‐Su Kim, Dan Luo, Young Hoon Roh

Small Methods· Volume 9· Issue 6

Abstract

Front Cover In article number 2401881, Luo, Roh, and co-workers introduce a metal ion-driven reconfiguration of DNA-MgPPi microhybrids into DNA-Au nanohybrids. These nanohybrids exhibit metal nanoparticle-based near-infrared absorbance and DNA aptamer-mediated targeted intracellular delivery, highlighting the successful integration of functional organic-inorganic molecules. This novel synthetic approach holds promise for a broad range of bio-related applications.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · RNA modifications and cancer · RNA and protein synthesis mechanisms

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Affiliations

Department of Biotechnology College of Life Science and Biotechnology Yonsei University 50 Yonsei‐ro Seodaemun‐gu Seoul 03722 South Korea

Department of Chemistry College of Science Yonsei University 50 Yonsei‐ro Seodaemun‐gu Seoul 03722 South Korea

Department of Biological and Environmental Engineering Cornell University Ithaca NY 14853 USA

References

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