Highly Sensitive Detection of Complicated Mutations of Drug Resistance in Mycobacterium tuberculosis Using a Simple, Accurate, Rapid, and Low‐Cost Tailored‐Design Competitive Wild‐Type Blocking Assay (Small Methods 3/2023)
Source abstract
Abstract
Highly Sensitive Detection In article number 2201322, Xu, Xu, Ying, and co-workers established a high-sensitive tailored-design competitive wild-type blocking assay for detecting as low as 1% complicated mutations of drug resistance in mycobacterium tuberculosis and its excellent sensitivity and specificity was validated on actual clinical samples. The simplicity, accuracy, rapidity, and low cost of the assay allow for great potential for clinical application, especially in high tuberculosis burden countries.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Tuberculosis Research and Epidemiology · Mycobacterium research and diagnosis · Phenothiazines and Benzothiazines Synthesis and Activities
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Affiliations
School of Biomedical Engineering/Med‐X Research Institute Shanghai Jiao Tong University Shanghai 200030 P. R. China
Department of Laboratory Medicine West China Hospital Sichuan University Chengdu 610041 P. R. China
Department of Clinical Laboratory Medicine People's Hospital of Ningxia Hui Autonomous Region (First Affiliated Hospital of Northwest Minzu University) Yinchuan 750002 P. R. China
References
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