Radical Reactions of Ynamides
Source abstract
Abstract
Abstract Ynamides are electron‐rich heteroatom‐substituted alkynes with C−C triple bond directly tethered to the amide group. Over the past decades, ynamides have proven to be versatile reagents for organic synthesis and have received extensive attention. Compared with the well‐established ionic reactions of ynamides, radical‐based ynamide reactions have been exploited relatively seldom. Herein, radical reactions of ynamides, classified by radical attack at the α‐position and β‐position of ynamides, are reviewed by highlighting the reaction selectivity, scope, mechanism, and applicability. The aim of this review is to provide a comprehensive summarization of these advances, casting light on the further development of ynamide chemistry.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Catalytic Alkyne Reactions · Catalytic C–H Functionalization Methods · Cyclopropane Reaction Mechanisms
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Key Laboratory for Chemical Biology of Fujian Province & State Key Laboratory of Physical Chemistry of Solid Surfaces College of Chemistry and Chemical Engineering Xiamen University Xiamen 361005 China
Institute of New Materials & Industry Technology College of Chemistry & Materials Engineering Wenzhou University Wenzhou 325035 China
State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China
Funding
National Natural Science Foundation of China · Natural Science Foundation of Fujian Province · Wenzhou Municipal Science and Technology Bureau
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