Surgical Navigation for Malignancies Guided by Near‐Infrared‐II Fluorescence Imaging
Source abstract
Abstract
Abstract Near‐infrared (NIR) fluorescence imaging is an emerging noninvasive imaging modality, with unique advantages in guiding tumor resection surgery, thanks to its high sensitivity and instantaneity. In the past decade, studies on the conventional NIR window (NIR‐I, 750–900 nm) have gradually focused on the second NIR window (NIR‐II, 1000–1700 nm). With its reduced light scattering, photon absorption, and auto‐fluorescence qualities, NIR‐II fluorescence imaging significantly improves penetration depths and signal‐to‐noise ratios in bio‐imaging. Recently, several studies have applied NIR‐II imaging to navigating cancer surgery, including localizing cancers, assessing surgical margins, tracing lymph nodes, and mapping important anatomical structures. These studies have exemplified the significant prospects of this new approach. In this review, several NIR‐II fluorescence agents and some of the complex applications for guiding cancer surgeries are summarized. Future prospects and the challenges of clinical translation are also discussed.
Source: crossref · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Photodynamic Therapy Research Studies · Photoacoustic and Ultrasonic Imaging
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Cancer Center & Department of Breast and Thyroid Surgery Xiang'an Hospital of Xiamen University School of Medicine Xiamen University Xiamen Fujian 361000 China
Key Laboratory for Endocrine‐Related Cancer Precision Medicine of Xiamen Xiang'an Hospital of Xiamen University Xiamen Fujian 361000 China
Clinical Central Research Core Xiang'an Hospital of Xiamen University Xiamen Fujian 361000 China
Key Laboratory of Design and Assembly of Functional Nanostructures Fujian Institute of Research on the Structure of Matter Chinese Academy of Sciences Fuzhou Fujian 350000 China
Cancer Research Center School of Medicine Xiamen University Xiamen Fujian 361000 China
Funding
Natural Science Foundation of Fujian Province · Natural Science Foundation of Guangdong Province · Xiamen University
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