Flexible and biocompatible high-performance solid-state micro-battery for implantable orthodontic system
Source abstract
Abstract
Abstract To augment the quality of our life, fully compliant personalized advanced health-care electronic system is pivotal. One of the major requirements to implement such systems is a physically flexible high-performance biocompatible energy storage (battery). However, the status-quo options do not match all of these attributes simultaneously and we also lack in an effective integration strategy to integrate them in complex architecture such as orthodontic domain in human body. Here we show, a physically complaint lithium-ion micro-battery (236 μg) with an unprecedented volumetric energy (the ratio of energy to device geometrical size) of 200 mWh/cm3 after 120 cycles of continuous operation. Our results of 90% viability test confirmed the battery’s biocompatibility. We also show seamless integration of the developed battery in an optoelectronic system embedded in a three-dimensional printed smart dental brace. We foresee the resultant orthodontic system as a personalized advanced health-care application, which could serve in faster bone regeneration and enhanced enamel health-care protection and subsequently reducing the overall health-care cost.
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Research context
OpenAlex topics: Advanced Sensor and Energy Harvesting Materials · Neuroscience and Neural Engineering · Wireless Power Transfer Systems
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (38)
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1. Hussain, A. M., Lizardo, E. B., Torres Sevilla, G. A., Nassar, J. M. & Hussain, M. M. Ultrastretchable and flexible copper interconnect-based smart patch for adaptive thermotherapy. Adv. Healthc. Mater. 4, 665–673 (2015).10.1002/adhm.201400647 ↗
2. Gao, W. et al. Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature 529, 509–514 (2016).10.1038/nature16521 ↗
3. Corea, J. R. et al. Screen-printed flexible MRI receive coils. Nat. Commun. 7, 10839 (2016).10.1038/ncomms10839 ↗
4. Xu, L. et al. 3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium. Nat. Commun. 5, 3329 (2014).
5. Kim, D.-H. et al. Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics. Nat. Mater. 9, 511–517 (2010).10.1038/nmat2745 ↗
6. Linford, R. & Schlindwein, W. Medical applications of solid state ionics. Solid State Ion. 177, 1559–1565 (2006).10.1016/j.ssi.2005.12.026 ↗
7. Passerini, S. & Owens, B. B. Medical batteries for external medical devices. J. Power Sources 97–98, 750–754 (2001).10.1016/S0378-7753(01)00602-4 ↗
8. Dodd, J., Kishiyama, C., Mukainakano, H., Nagata, M. & Tsukamoto, H. Performance and management of implantable lithium battery systems for left ventricular assist devices and total artificial hearts. J. Power Sources 146, 784–787 (2005).10.1016/j.jpowsour.2005.03.168 ↗
9. Passerini, S., Owens, B. B. & Coustier, F. Lithium-ion batteries for hearing aid applications: I. Design and performance. J. Power Sources 89, 29–39 (2000).10.1016/S0378-7753(00)00378-5 ↗
10. Volkmann, J., Herzog, J., Kopper, F. & Deuschl, G. Introduction to the programming of deep brain stimulators. Mov. Disord. 17, S181–S187 (2002).10.1002/mds.10162 ↗
11. Wang, X. et al. Flexible energy-storage devices: design consideration and recent progress. Adv. Mater. 26, 4763–4782 (2014).10.1002/adma.201400910 ↗
12. Li, L. et al. A foldable lithium–sulfur battery. ACS Nano. 9, 11342–11350 (2015).10.1021/acsnano.5b05068 ↗
13. Huang, Y. et al. From industrially weavable and knittable highly conductive yarns to large wearable energy storage textiles. ACS Nano 9, 4766–4775 (2015).10.1021/acsnano.5b00860 ↗
14. Song, S.-W. et al. High rate-induced structural changes in thin-film lithium batteries on flexible substrate. J. Power Sources 195, 8275–8279 (2010).10.1016/j.jpowsour.2010.06.113 ↗
15. Song, Z. et al. Kirigami-based stretchable lithium-ion batteries. Sci. Rep. 5, 10988 (2015).10.1038/srep10988 ↗
16. Xie, K. & Wei, B. Materials and structures for stretchable energy storage and conversion devices. Adv. Mater. 26, 3592–3617 (2014).10.1002/adma.201305919 ↗
17. Song, Z. et al. Origami lithium-ion batteries. Nat. Commun. 5, 3140 (2014).10.1038/ncomms4140 ↗
18. Aliahmad, N., Agarwal, M., Shrestha, S. & Varahramyan, K. Paper-based lithium-ion batteries using carbon nanotube-coated wood microfibers. IEEE Trans. Nanotechnol. 12, 408–412 (2013).10.1109/TNANO.2013.2252922 ↗
19. Pereira, T. et al. The performance of thin-film Li-ion batteries under flexural deflection. J. Micromech. Microeng. 16, 2714 (2006).10.1088/0960-1317/16/12/026 ↗
20. Zhou, G., Li, F. & Cheng, H.-M. Progress in flexible lithium batteries and future prospects. Energy Environ. Sci. 7, 1307–1338 (2014).10.1039/C3EE43182G ↗
21. Lee, S. H., Jeong, C. K., Hwang, G.-T. & Lee, K. J. Self-powered flexible inorganic electronic system. Nano Energy 14, 111–125 (2015).10.1016/j.nanoen.2014.12.003 ↗
22. Si, W. et al. A single rolled-up si tube battery for the study of electrochemical kinetics, electrical conductivity, and structural integrity. Adv. Mater. 26, 7973–7978 (2014).10.1002/adma.201402484 ↗
23. Xu, S. et al. Stretchable batteries with self-similar serpentine interconnects and integrated wireless recharging systems. Nat. Commun. 4, 1543 (2013).10.1038/ncomms2553 ↗
24. Yan, C. & Lee, P. S. Stretchable energy storage and conversion devices. Small 10, 3443–3460 (2014).10.1002/smll.201302806 ↗
25. Lee, Y.-H. et al. Wearable textile battery rechargeable by solar energy. Nano Lett. 13, 5753–5761 (2013).10.1021/nl403860k ↗
26. Neudecker, B. J., Dudney, N. J. & Bates, J. B. “Lithium‐free” thin‐film battery with in situ plated Li anode. J. Electrochem. Soc. 147, 517–523 (2000).10.1149/1.1393226 ↗
27. Kutbee, A. T., Ghoneim, M. T., Ahmad, S. M. & Hussain, M. M. Free-form flexible lithium-ion microbattery. IEEE Trans. Nanotechnol. 15, 402–408 (2016).10.1109/TNANO.2016.2537338 ↗
28. Koo, M. et al. Bendable inorganic thin-film battery for fully flexible electronic systems. Nano Lett. 12, 4810–4816 (2012).10.1021/nl302254v ↗
29. Ning, F., Li, S., Xu, B. & Ouyang, C. Strain tuned Li diffusion in LiCoO2 material for Li ion batteries: A first principles study. Solid State Ion. 263, 46–48 (2014).10.1016/j.ssi.2014.05.008 ↗
30. Schmalz, G. & Arenholt-Bindslev, D. Biocompatibility of Dental Materials. (Springer Berlin Heidelberg, 2009).
31. Patzelt, S. B. M., Emmanouilidi, A., Stampf, S., Strub, J. R. & Att, W. Accuracy of full-arch scans using intraoral scanners. Clin. Oral Investig. 18, 1687–1694 (2014).10.1007/s00784-013-1132-y ↗
32. McDowall, F. Introduction to dental materials, 4th edition. Br. Dent. J. 215, 100–100 (2013).10.1038/sj.bdj.2013.734 ↗
33. Desmet, KristinaD. et al. Clinical and experimental applications of NIR-LED photobiomodulation. Photomed. Laser Surg. 24, 121–128 (2006).10.1089/pho.2006.24.121 ↗
34. Park, J. S. & Park, K.-H. Light enhanced bone regeneration in an athymic nude mouse implanted with mesenchymal stem cells embedded in PLGA microspheres. Biomater. Res. 20, 4 (2016).10.1186/s40824-016-0051-9 ↗
35. Hoogeveen, E. J., Jansma, J. & Ren, Y. Surgically facilitated orthodontic treatment: A systematic review. Am. J. Orthod. Dentofac. Orthop. 145, S51–S64 (2014).10.1016/j.ajodo.2013.11.019 ↗
36. Wilcko, M. T., Wilcko, W. M., Pulver, J. J., Bissada, N. F. & Bouquot, J. E. Accelerated osteogenic orthodontics technique: a 1-stage surgically facilitated rapid orthodontic technique with alveolar augmentation. J. Oral Maxillofac. Surg. 67, 2149–2159 (2009).10.1016/j.joms.2009.04.095 ↗
37. Research, B. Light Accelerated Smiles, http://staging.bioluxresearch.com/bioluxwww/ (2015).
38. Brawn, P. R. Method and apparatus for regulating tooth movement. WO2010142031 A1 (Google Patents, 2010).