journal article·2019-07-30Open access

Wireless organic electronic ion pumps driven by photovoltaics

Marie Jakešová, Theresia Arbring Sjöström, Vedran Đerek, David Poxson, Magnus Berggren, Eric Daniel Głowacki, Daniel T. Simon

npj Flexible Electronics· Volume 3· Issue 1

Abstract

Abstract The organic electronic ion pump (OEIP) is an emerging bioelectronic technology for on-demand and local delivery of pharmacologically active species, especially targeting alkali ions, and neurotransmitters. While electrical control is advantageous for providing precise spatial, temporal, and quantitative delivery, traditionally, it necessitates wiring. This complicates implantation. Herein, we demonstrate integration of an OEIP with a photovoltaic driver on a flexible carrier, which can be addressed by red light within the tissue transparency window. Organic thin-film bilayer photovoltaic pixels are arranged in series and/or vertical tandem to provide the 2.5–4.5 V necessary for operating the high-resistance electrophoretic ion pumps. We demonstrate light-stimulated transport of cations, ranging in size from protons to acetylcholine. The device, laminated on top of the skin, can easily be driven with a red LED emitting through a 1.5-cm-thick finger. The end result of our work is a thin and flexible integrated wireless device platform.
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Research context

OpenAlex topics: Conducting polymers and applications · Advanced Sensor and Energy Harvesting Materials · Advanced Memory and Neural Computing

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