journal article·2017-10

Light‐Induced PEGylation and Functionalization of Semiconductor Polymer Dots

Haobin Chen, Hua Zhou, Xiaoju Men, Kai Sun, Zezhou Sun, Xiaofeng Fang, Changfeng Wu

ChemNanoMat· Volume 3· Issue 10
Publisher page

Abstract

Abstract A semiconductor polymer with side‐chain oxetane groups was synthesized to form highly fluorescent, functionalized, and ultra‐stable polymer dots (Pdots). A facile light‐induced strategy covalently links functional polyethylene glycol (PEG) molecules to polymer dots while simultaneously providing functional groups for bioconjugation. The influence of photo‐crosslinkable side‐chains and PEG molecules on the properties and performance of Pdots was systematically investigated. The Pdots functionalized by photo‐crosslinking show specific labeling and negligible non‐specific binding as compared to non‐functionalized Pdots. The results provide a viable strategy for nanoparticle assembly and functionalization.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Luminescence and Fluorescent Materials · Nanoplatforms for cancer theranostics · Quantum Dots Synthesis And Properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

State Key Laboratory on Integrated Optoelectronics College of Electronic Science and Engineering Jilin University Changchun Jilin 130012 China

Department of Biomedical Engineering Southern University of Science and Technology Shenzhen Guangdong 518055 China

Funding

National Natural Science Foundation of China

References (36)

Show source-provided references
1. 10.1021/acsnano.6b0016810.1021/acsnano.6b00168 ↗
2. 10.1021/acs.analchem.6b0467210.1021/acs.analchem.6b04672 ↗
3. 10.1039/C4SC03062A10.1039/C4SC03062A ↗
4. 10.1021/cr100132y10.1021/cr100132y ↗
5. 10.1039/c3cs60036j10.1039/c3cs60036j ↗
6. 10.1039/c3cc44048f10.1039/c3cc44048f ↗
7. 10.1002/anie.20120513310.1002/anie.201205133 ↗
8. 10.1002/ange.20120513310.1002/ange.201205133 ↗
9. 10.1021/acsnano.6b0290810.1021/acsnano.6b02908 ↗
10. 10.1021/acs.chemmater.6b0373810.1021/acs.chemmater.6b03738 ↗
11. 10.1021/acsami.6b1432510.1021/acsami.6b14325 ↗
12. 10.1021/acsnano.6b0594910.1021/acsnano.6b05949 ↗
13. 10.1002/advs.20160048110.1002/advs.201600481 ↗
14. 10.1002/cnma.20150017110.1002/cnma.201500171 ↗
15. 10.1002/adma.20150568110.1002/adma.201505681 ↗
16. 10.1021/ja100217910.1021/ja1002179 ↗
17. 10.1002/anie.20100311110.1002/anie.201003111 ↗
18. 10.1002/ange.20100311110.1002/ange.201003111 ↗
19. 10.1021/nn301308w10.1021/nn301308w ↗
20. 10.1039/C5TB02348C10.1039/C5TB02348C ↗
21. 10.1016/j.jconrel.2016.01.00410.1016/j.jconrel.2016.01.004 ↗
22. 10.1002/anie.20100426010.1002/anie.201004260 ↗
23. 10.1002/ange.20100426010.1002/ange.201004260 ↗
24. 10.1002/smll.20080071410.1002/smll.200800714 ↗
25. 10.1002/adfm.20110223410.1002/adfm.201102234 ↗
26. 10.1016/S0021-9258(17)40291-210.1016/S0021-9258(17)40291-2 ↗
27. 10.1021/bc100070g10.1021/bc100070g ↗
28. 10.1038/nrd259110.1038/nrd2591 ↗
29. 10.1039/b902394a10.1039/b902394a ↗
30. 10.1039/C4SC03959A10.1039/C4SC03959A ↗
31. 10.1016/S0142-9612(01)00043-610.1016/S0142-9612(01)00043-6 ↗
32. 10.1021/ja076069p10.1021/ja076069p ↗
33. 10.1021/nn800590n10.1021/nn800590n ↗
34. 10.1021/acsami.5b0374910.1021/acsami.5b03749 ↗
35. 10.1021/acs.chemmater.6b0274610.1021/acs.chemmater.6b02746 ↗
36. 10.1021/ja107196s10.1021/ja107196s ↗