JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Mengqian Guo, Qiang Jiang, Wei Zhang, Saman Jalili

Abstract not available. Bibliographic information is searchable.

Yuan Hu, Lijuan Wei, Haijun Yang, Jianhong Sun et al.

Wet age-related macular degeneration (Wet AMD) is a major cause of vision loss and has been linked to abnormal choroidal neovascularization (CNV). Current therapies require frequent intravitreal injections, which leads to poor patient adherence. Herein, this study was designed to investigate rapamycin-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles, which rep…

Jokin Zubizarreta Oteiza, Yannick Krieger, Daniel Seiler, Philippe C. Cattin et al.

Abstract Fused filament fabrication (FFF) of high-performance thermoplastic composites for medical applications remains challenging due to the need to meet geometric precision, mechanical, and functional requirements. This study presents the first systematic evaluation of FFF radiopaque barium sulfate-reinforced polyetheretherketone (BaSO₄-PEEK) for patient-specific orbital rec…

Yueming Hu, Xiaolei Han

Lung cancer is one of the leading causes of cancer-related deaths worldwide. The mortality rate can be reduced through the development of novel therapeutic drugs for lung cancer. In this study, we developed nanoparticles (NPs) consisting of polyethylene glycol (PEG)-cloaked mesoporous polydopamine (MP) loaded with indocyanine green (IG) and talazoparib (TZ), designed to combine…

Wanting Wu, Suping Yu, Nanjin Li, Shan Liang et al.

We developed a novel glaucoma drainage tube, designated as GDTI-50H. The outer opening end of the drainage tube is provided with multiple drainage holes, which allows for normal drainage of aqueous humor through the remaining holes when one of the drainage holes becomes blocked. It is potentially enhancing the sustained drainage efficiency. Fourteen New Zealand white rabbits we…

R. Sri Manjari, Varsha Jayaprakash, Meghna Mohandas, Abhirami Preetha et al.

A gastric ulcer (GU) that leads to acute or persistent bleeding poses a considerable risk of fatalities. Despite their overall primacy, the current treatments for GU have major downsides of incomplete healing, antibiotic resistance, and secondary injury. To address these challenges, researchers have turned their attention to hydrogels to solve the therapeutic bottleneck of GU t…

Frank Alifui-Segbaya

Assessing the degree of conversion is important for evaluating processing quality in additively manufactured dental methacrylates. However, the widely used attenuated total reflectance-Fourier transform infrared (ATR-FTIR) method, based on the 1637/1608 cm⁻¹ ratio, may be unstable in contemporary methacrylate systems because of spectral congestion and the formulation-dependent …

Shao-Jun Cai, Zi-Han Tang, Teng-Hong Liu, Shou-Yi Yan et al.

Thyroid cancer is a significant worldwide health challenge, requiring sophisticated treatment strategies to minimize off-target side effects. In this study, we developed biodegradable polyethylene glycol (PEG)-coated manganese dioxide (MD) nanomaterials, coupled with carminic acid (CA), for thyroid cancer chemo-photodynamic therapy (PDT). The pH-responsive PMD-CA NMs facilitate…

Farah Asa’ad

Abstract not available. Bibliographic information is searchable.

Haoran Guo, Ruixing Wan, Qingqing Qin, Wenqiang Liang et al.

Cisplatin is a commonly used chemotherapeutic agent for the treatment of diverse malignancies; however, its clinical use often results in skeletal muscle atrophy (SMA). Excessive generation of reactive oxygen species (ROS) and persistent unsettled inflammation are significant contributors to cisplatin (CPT)-induced skeletal muscle atrophy (CiSMA). Nanoparticles capable of scave…

Farzaneh Saeedi Landi, Mahdi Gholami, Negar Abdollahzadeh, Fariba Esmaeili et al.

Topical minoxidil is typically administered over an extended period for the therapeutic management of androgenic alopecia. Given the adverse effects of commercial preparations of minoxidil (i.e., minoxidil solution), researchers are increasingly looking for alternative preparations that offer enhanced efficacy and reduced side effects. To do so, in this study, nanoemulsions con…

Xuanfu Chi, Chaowei Wu, Feifei Ni, Tai Zeng et al.

Abstract Coronary artery disease (CAD) and myocardial infarction (MI) feature a highly dynamic inflammatory milieu. While reperfusion remains essential, it does not sufficiently correct immune dysregulation or prevent adverse remodeling. Biomaterials offer a complementary strategy by enabling spatiotemporally controlled immunomodulation and tissue repair. By providing localized…

Yang Yang, Jinan Wu, Guanyi Liu, Junsi Luo et al.

Tissue regeneration is a significant medical challenge in repairing damaged tissues and organs, driving the need for novel biomaterials with both excellent bioactivity and mechanical properties. Tantalum (Ta) is a promising biomedical metal due to its mechanical stability, biocompatibility, and biological functions. However, the high density, cost, and processing difficulty of …

Ananthika Vijayan, Aswin Gopakumar, Sobha V. Nair, Balakrishnan Shankar et al.

Hydroxyapatite (HAp) derived from bovine bone waste was used to develop a bioactive composite scaffold incorporating polyethylene glycol (PEG), ZnO nanoparticles, and ascorbic acid (AA). This study aimed to fabricate a PEG-based HAp composite enriched with ZnO and AA and to evaluate the influence of these additives on the structural characteristics and biological performance of…

Saeed Sharifpoor Kermani, Jens Wippermann, Priya Veluswamy, Max Wacker

Abstract Coronary artery bypass grafting (CABG) via autologous vein or artery is still the gold standard surgery operative revascularization. However autologous vein/artery may represent some limitations like varicose veins or unavailability of veins due to reoperations especially in older patients. consequently, the research focus directed towards identification and characteri…

Nasera Rizwana, Poorvi Shivakumar, Vipul Agarwal, Manasa Nune

Peripheral nerve injury (PNI) is a common neurological problem that can hamper the quality of life causing sensory and motor dysfunction. While small peripheral nerve defects get repaired by themselves, larger defects require tissue engineering substitutes to bridge the nerve gap. One of the recent technologies and strategies to address the peripheral nerve regeneration is thro…

Faleh Abushahba, Sherif A. Mohamad, Adrian Stiller, Polina Sinitsyna et al.

This study evaluated hydrothermally induced nanostructured TiO 2 coatings (HT-TiO 2 ) on Grade 1 titanium (Ti) with a focus on surface mineralization behavior and early cellular responses. Rapid mineralization (RM) was achieved by immersion in modified simulated body fluid (m-SBF). Ti discs were subjected to hydrothermal treatment (HT) to produce a TiO 2 coating, then mineraliz…

Naghmeh Nademi, Pouriya Toloee, Mojdeh Mohseni, Mostafa Dahmardehei et al.

Designing multifunctional wound dressings with admirable mechanical virtues, appropriate electrical conductivity, and good antibacterial performance is critical for preventing infection and promoting tissue repair. Herein, a conductive gellan–agar composite film reinforced with chopped PCL–gelatin electrospun fibers containing polyaniline–graphene (PAG) and loaded with ciproflo…

Huan Wei, Tomáš Riedel, Zuzana Riedelová, Melanie Wolf et al.

Flow diverters play an important role in the endovascular treatment of intracranial aneurysms; however, their use can be associated with thromboembolic complications. Thus, in recent years, flow diverters with surface coatings have been developed to prevent thrombus-related complications. In this study, the hemocompatibility of the flow diverters FRED X with poly(2-methoxyethyl…

Qihong Huang, Ke Chen, Xuhui Liu, Fugang Qi et al.

Severe rib fractures often require surgical plate fixation, but non-biodegradable implants typically necessitate a second surgery for removal. Although AZ31 magnesium alloy is a biodegradable medical material, its excessively rapid in vivo degradation makes it difficult to meet the requirements for fracture fixation in high-load, dynamic environments such as the ribs. To addres…