X-ray imaging technique using colloid solution of Au/silica core-shell nanoparticles
Source abstract
Abstract
This work describes X-ray imaging of mouse using a colloid solution of silica-coated Au (Au/SiO 2 ) nanoparticles. A colloid solution of Au nanoparticles with a size of 16.9 nm was prepared using hydrogen tetrachloroaurate (III) trihydrate as Au source and sodium citrate as reducing reagent. Silica coating of the Au nanoparticles was performed by modifying the Au nanoparticle surface with (3-aminopropyl)trimethoxysilane and then by depositing silica nuclei generated through a sol–gel reaction of tetraethyl orthosilicate in water/ethanol initiated with sodium hydroxide on the surface-modified surface, which produced Au/SiO 2 particles with a size of 136.4 nm. A computed tomography value of the Au/SiO 2 colloid solution with an Au concentration of 0.036 M was as high as 1,184.8 Hounsfield units, which was quite higher than that of a commercial X-ray contrast agent with the same iodine concentration as the Au concentration. Tissues of mouse could be imaged by injecting the Au/SiO 2 particle colloid solution into them.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Nanoplatforms for cancer theranostics · Gold and Silver Nanoparticles Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (48)
Show source-provided references
1. Bellani G, Caironi P: Lung imaging during acute respiratory distress syndrome: CT- and PET-scanning. Trends Anaesth Crit Care 2011, 1: 203–209.10.1016/j.tacc.2011.05.006 ↗
2. Duwek HC, Spitzer H, Weitzen R, Apter S: A biologically-based algorithm for companding computerized tomography (CT) images. Comput Biol Med 2011, 41: 367–379.10.1016/j.compbiomed.2011.03.015 ↗
3. Ruschin M, Komljenovic PT, Ansell S, Ménard C, Bootsma G, Cho YB, Chung C, Jaffray D: Cone beam computed tomography image guidance system for a dedicated intracranial radiosurgery treatment unit. Int J Radiat Oncol Biol Phys 2013, 85: 243–250.10.1016/j.ijrobp.2012.03.022 ↗
4. Lee SJ, Jung SY, Ahn S: Flow tracing microparticle sensors designed for enhanced X-ray contrast. Biosens Bioelectron 2010, 25: 1571–1578.10.1016/j.bios.2009.11.010 ↗
5. Hwang UJ, Shin DH, Kim TH, Moon SH, Lim YK, Jeong H, Rah JE, Kim SS, Kim JY, Kim DY, Park SY, Cho KH: The effect of a contrast agent on proton beam range in radiotherapy planning using computed tomography for patients with locoregionally advanced lung cancer. Int J Radiat Oncol Biol Phys 2011, 81: e317-e324.10.1016/j.ijrobp.2011.02.025 ↗
6. Rustighi I, Donati I, Ferluga M, Campa C, Pasqua AE, Rossib M, Paoletti S: Borate complexes of X-ray iodinated contrast agents: characterization and sorption studies for their removal from aqueous media. J Hazard Mater 2012, 205–206: 10–16.10.1016/j.jhazmat.2011.10.084 ↗
7. Thomsen HS: Contrast media safety - an update. Eur J Radiol 2011, 80: 77–82.10.1016/j.ejrad.2010.12.104 ↗
8. Ichikawa T, Motosugi U, Morisaka H, Sou H, Onohara K, Sano K, Araki T: Optimal iodine dose for 3-dimensional multidetector-row CT angiography of the liver. Eur J Radiol 2012, 81: 2450–2455.10.1016/j.ejrad.2011.06.022 ↗
9. Li X, Anton N, Zuber G, Zhao M, Messaddeq N, Hallouard F, Fessi H, Vandamme TF: Iodinated a-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging. Biomater 2013, 34: 481–491.10.1016/j.biomaterials.2012.09.026 ↗
10. Malarkodi C, Rajeshkumar S, Vanaja M, Paulkumar K, Gnanajobitha G, Annadurai G: Eco-friendly synthesis and characterization of gold nanoparticles using Klebsiella pneumoniae . J Nanostruct Chem 2013, 3: 30.10.1186/2193-8865-3-30 ↗
11. Rajeshkumar S, Malarkodi C, Gnanajobitha G, Paulkumar K, Vanaja M, Kannan C, Annadurai G: Seaweed-mediated synthesis of gold nanoparticles using Turbinaria conoides and its characterization. J Nanostruc Chem 2013, 3: 44.10.1186/2193-8865-3-44 ↗
12. Park JA, Kim HK, Kim JH, Jeong SW, Jung JC, Lee GH, Lee J, Chang Y, Kim TJ: Gold nanoparticles functionalized by gadolinium-DTPA conjugate of cysteine as a multimodal bioimaging agent. Bioorg Med Chem Lett 2010, 20: 2287–2291.10.1016/j.bmcl.2010.02.002 ↗
13. Cho EC, Glaus C, Chen J, Welch MJ, Xia Y: Inorganic nanoparticle-based contrast agents for molecular imaging. Trends Mol Med 2010, 16: 561–573.10.1016/j.molmed.2010.09.004 ↗
14. Wang H, Zheng L, Peng C, Guo R, Shen M, Shi X, Zhang G: Computed tomography imaging of cancer cells using acetylated dendrimer-entrapped gold nanoparticles. Biomater 2011, 32: 2979–2988.10.1016/j.biomaterials.2011.01.001 ↗
15. Ahn S, Jung SY, Seo E, Lee SJ: Gold nanoparticle-incorporated human red blood cells (RBCs) for X-ray dynamic imaging. Biomater 2011, 32: 7191–7199.10.1016/j.biomaterials.2011.05.023 ↗
16. Menk RH, Schültke E, Hall C, Arfelli F, Astolfo A, Rigon L, Round A, Ataelmannan K, MacDonald SR, Juurlink BHJ: Gold nanoparticle labeling of cells is a sensitive method to investigate cell distribution and migration in animal models of human disease. Nanomed Nanotechnol Biol Med 2011, 7: 647–654.10.1016/j.nano.2011.01.010 ↗
17. Roessl E, Cormode D, Brendel B, Engel KJ, Martens G, Thran A, Fayad Z, Proks R: Preclinical spectral computed tomography of gold nano-particles. Nucl Instrum Met Phys Res A 2011, 648: S259-S264.10.1016/j.nima.2010.11.072 ↗
18. Zhang XD, Wu D, Shen X, Chen J, Sun YM, Liu PX, Liang XJ: Size-dependent radiosensitization of PEG-coated gold nanoparticles for cancer radiation therapy. Biomater 2012, 33: 6408–6419.10.1016/j.biomaterials.2012.05.047 ↗
19. Peng C, Zheng L, Chen Q, Shen M, Guo R, Wang H, Cao X, Zhang G, Shi X: PEGylated dendrimer-entrapped gold nanoparticles for in vivo blood pool and tumor imaging by computed tomography. Biomater 2012, 33: 1107–1119.10.1016/j.biomaterials.2011.10.052 ↗
20. Kim D, Jon S: Gold nanoparticles in image-guided cancer therapy. Inorg Chim Acta 2012, 393: 154–164.10.1016/j.ica.2012.07.001 ↗
21. Tedesco S, Doyle H, Blasco J, Redmond G, Sheehan D: Oxidative stress and toxicity of gold nanoparticles in Mytilus edulis . Aquat Toxicol 2010, 100: 178–186.10.1016/j.aquatox.2010.03.001 ↗
22. Ahamed M, AlSalhi MS, Siddiqui MKJ: Silver nanoparticle applications and human health. Clin Chim Acta 2010, 411: 1841–1848.10.1016/j.cca.2010.08.016 ↗
23. Farkas J, Christian P, Urrea JAG, Roos N, Hassellöv M, Tollefsen KE, Thomas KV: Effects of silver and gold nanoparticles on rainbow trout ( Oncorhynchus mykiss ) hepatocytes. Aquat Toxicol 2010, 96: 44–52.10.1016/j.aquatox.2009.09.016 ↗
24. Lasagna-Reeves C, Gonzalez-Romero D, Barria MA, Olmedo I, Clos A, Ramanujam VMS, Urayama A, Vergara L, Kogan MJ, Soto C: Bioaccumulation and toxicity of gold nanoparticles after repeated administration in mice. Biochem Biophys Res Commun 2010, 393: 649–655.10.1016/j.bbrc.2010.02.046 ↗
25. Han X, Gelein R, Corson N, Mercer PW, Jiang J, Biswas P, Finkelstein JN, Elder A, Oberdörster G: Validation of an LDH assay for assessing nanoparticle toxicity. Toxicol 2011, 287: 99–104.10.1016/j.tox.2011.06.011 ↗
26. Park MVDZ, Neigh AM, Vermeulen JP, de la Fonteyne LJJ, Verharen HW, Briedé JJ, Van Loveren H, De Jong WH: The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles. Biomater 2011, 32: 9810–9817.10.1016/j.biomaterials.2011.08.085 ↗
27. Schulz M, Ma-Hock L, Brill S, Strauss V, Treumann Gröters SS, van Ravenzwaay B, Landsiedel R: Investigation on the genotoxicity of different sizes of gold nanoparticles administered to the lungs of rats. Mutat Res 2012, 745: 51–57.10.1016/j.mrgentox.2011.11.016 ↗
28. Nymark P, Catalán J, Suhonen S, Järventaus H, Birkedal R, Clausen PA, Jensen KA, Vippola M, Savolainena K, Norppa H: Genotoxicity of polyvinylpyrrolidone-coated silver nanoparticles in BEAS 2B cells. Toxicol in press in press
29. Lu Y, Yin Y, Li ZY, Xia Y: Synthesis and self-assembly of Au@SiO 2 core-shell colloids. Nano Lett 2002, 2: 785–788.10.1021/nl025598i ↗
30. Xu J, Perry CC: A novel approach to Au@SiO 2 core-shell spheres. J Non-Cryst Solid 2007, 353: 1212–1215.10.1016/j.jnoncrysol.2007.01.005 ↗
31. Ye J, Broek BV, Palma RD, Libaers W, Clays K, Roy WV, Borghs G, Maes G: Surface morphology changes on silica-coated gold colloids. Colloids Surf A 2008, 322: 225–233.10.1016/j.colsurfa.2008.03.033 ↗
32. Wu Z, Liang J, Ji X, Yang W: Preparation of uniform Au@SiO 2 particles by direct silica coating on citrate-capped Au nanoparticles. Colloids Surf A 2011, 392: 220–224.10.1016/j.colsurfa.2011.09.059 ↗
33. Wang TT, Chai F, Wang CG, Li L, Liu HY, Zhang LY: Fluorescent hollow/rattle-type mesoporous Au@SiO 2 nanocapsules for drug delivery and fluorescence imaging of cancer cells. J Colloid Inter Sci 2011, 358: 109–115.10.1016/j.jcis.2011.02.023 ↗
34. Huang CC, Huang CH, Kuo IT, Chau LK, Yang TS: Synthesis of silica-coated gold nanorod as Raman tags by modulating cetyltrimethylammonium bromide concentration. Colloids Surf A 2012, 409: 61–68.10.1016/j.colsurfa.2012.06.003 ↗
35. Yu D, Zeng Y, Qi Y, Zhou T, Shi G: A novel electrochemical sensor for determination of dopamine based on AuNPs@SiO 2 core-shell imprinted composite. Biosens Bioelectron 2012, 38: 270–277.10.1016/j.bios.2012.05.045 ↗
36. Fülöp E, Nagy N, Deák A, Bársony I: Langmuir–Blodgett films of gold/silica core/shell nanorods. Thin Solid Films 2012, 520: 7002–7005.10.1016/j.tsf.2012.07.097 ↗
37. Shen S, Tang H, Zhang X, Ren J, Pang Z, Wang D, Gao H, Qian Y, Jiang X, Yang W: Targeting mesoporous silica-encapsulated gold nanorods for chemo-photothermal therapy with near-infrared radiation. Biomater 2013, 34: 3150–3158.10.1016/j.biomaterials.2013.01.051 ↗
38. Khlebtsov BN, Khanadeev VA, Panfilova EV, Inozemtseva OA, Burov AM, Khlebtsov NG: A simple Mie-type model for silica-coated gold nanocages. J Quant Spectrosc Ra 2013, 121: 23–29.10.1016/j.jqsrt.2013.03.001 ↗
39. Mine E, Yamada A, Kobayashi Y, Konno M, Liz-Marzán LM: Direct coating of gold nanoparticles with silica by a seeded polymerization technique. J Colloid Interface Sci 2003, 264: 385–390.10.1016/S0021-9797(03)00422-3 ↗
40. Kobayashi Y, Inose H, Nakagawa T, Gonda K, Takeda M, Ohuchi N, Kasuya A: Control of shell thickness in silica-coating of Au nanoparticles and their X-ray imaging properties. J Colloid Interface Sci 2011, 358: 329–333.10.1016/j.jcis.2011.01.058 ↗
41. Kobayashi Y, Inose H, Nakagawa T, Gonda K, Takeda M, Ohuchi N, Kasuya A: Synthesis of Au-silica core-shell particles by sol–gel process. Surf Eng 2012, 28: 129–133.10.1179/1743294411Y.0000000069 ↗
42. Kobayashi Y, Inose H, Nagasu R, Nakagawa T, Kubota Y, Gonda K, Ohuchi N: X-ray imaging technique using colloid solution of Au/silica/poly(ethylene glycol) nanoparticles. Mater Res Innov in press in press
43. Zhang A, Tu Y, Qin S, Li Y, Zhou J, Chen N, Lu Q, Zhang B: Gold nanoclusters as contrast agents for fluorescent and X-ray dual-modality imaging. J Colloid Interface Sci 2012, 372: 239–244.10.1016/j.jcis.2012.01.005 ↗
44. Hallouard F, Anton N, Choquet P, Constantinesco A, Vandamme T: Iodinated blood pool contrast media for preclinical X-ray imaging applications - a review. Biomater 2010, 31: 6249–6268.10.1016/j.biomaterials.2010.04.066 ↗
45. Parveen S, Sahoo SK: Long circulating chitosan/PEG blended PLGA nanoparticle for tumor drug delivery. Eur J Pharmacol 2011, 670: 372–383.10.1016/j.ejphar.2011.09.023 ↗
46. Dufort S, Sancey L, Coll JL: Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution. Adv Drug Deliv Rev 2012, 64: 179–189.10.1016/j.addr.2011.09.009 ↗
47. Stolnik S, Illum L, Davis SS: Long circulating microparticulate drug carriers. Adv Drug Deliv Rev 2012, 64: 290–301.10.1016/j.addr.2012.09.029 ↗
48. Bauer S, Schmuki P, von der Mark K, Park J: Engineering biocompatible implant surfaces: part I: materials and surfaces. Prog Mater Sci 2013, 58: 261–326.10.1016/j.pmatsci.2012.09.001 ↗