Facile fabrication of palladium and ruthenium nanoparticles incorporated into core–shell: investigation of proliferation and apoptosis induction in prostate cancer cells
Source abstract
Abstract
The most common disease among males diagnosed in the USA is prostate cancer, and managing it remains difficult in routine oncology practice. Therefore, people with prostate cancer demand improved therapeutic approaches. We effectively fabricated palladium, and ruthenium nanoparticles incorporated into core–shell Al2O3@SiO2@Fe3O4 (ASF) were effectively fabricated based on MOF MIL(Al)96. The fabricated nanoparticles were examined the various analytical and spectroscopic methods (FT-IR, UV–Vis, TEM, and SEM). The dynamic light scattering (DLS) method examined the particle size and stability of the nanoparticles. The cytotoxic efficiency of the nanoparticles was examined by in vitro against PC3pip and LNCAP human prostate cancer cells by MTT assay. Further, the fluorescence staining methods investigated the cells’ morphological changes and nuclear damage. The outcomes reveal that all fabricated nanoparticles will be potentially promising as anticancer agents for prostate cancer.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Dendrimers and Hyperbranched Polymers · Nanocluster Synthesis and Applications
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (54)
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