Structural, physicomechanical, and in vitro biodegradation studies on Sr-doped bioactive ceramic
Source abstract
Abstract
Abstract This study aimed to investigate the effect of Sr substitution on the structure, mechanical properties, bioactivity, and biodegradation of akermanite (Ca2MgSi2O7). Samples were synthesized through solid-state synthesis followed by heat treatment at 1200 °C and 1250 °C. X-ray diffraction patterns showed that Sr substitution did not change the Ca2MgSi2O7 phase. Fourier transform infrared spectra demonstrated that the silicate structure of Ca2MgSi2O7 also remained unchanged. The field emission scanning electron microscopy revealed that partial Sr substitution enhanced the density of Ca2MgSi2O7 and reduced the grain size. The optimum dopant with the highest mechanical properties was 0.05Sr. However, the mechanical properties decreased beyond 0.05Sr because of the large grain size. The mechanical properties of Sr-substituted samples sintered at 1250 °C were lower due to high liquid phase formation. Sr substitution supported apatite formation and controlled Ca2MgSi2O7 degradation after the samples were soaked in simulated body fluid solution (SBF).
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Orthopaedic implants and arthroplasty
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (49)
Show source-provided references
1. Bioceramics: from bone substitutes to nanoparticles for drug delivery10.1515/pac-2018-0505 ↗
2. Dissolution behavior of CaO-MgO-SiO2-based bioceramic powders in simulated physiological environments10.1016/j.ceramint.2017.03.130 ↗
3. Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications10.1016/j.cossms.2014.02.004 ↗
4. Synthesis and apatite-formation ability of akermanite10.1016/j.matlet.2004.02.039 ↗
5. A novel and economical route for synthesizing akermanite (Ca2MgSi2O7) nano-bioceramic10.1016/j.msec.2016.11.021 ↗
6. Toughening and strengthening mechanisms of porous akermanite scaffolds reinforced with nano-titania10.1039/C4RA12095G ↗
7. The incorporation of strontium and zinc into a calcium–silicon ceramic for bone tissue engineering10.1016/j.biomaterials.2010.01.024 ↗
8. Silicon carbide whiskers reinforced akermanite scaffolds for tissue engineering10.1039/C4RA07474B ↗
9. Akermanite scaffolds reinforced with boron nitride nanosheets in bone tissue engineering10.1007/s10856-015-5513-4 ↗
10. A combined nanostructure constructed by graphene and boron nitride nanotubes reinforces ceramic scaffolds10.1016/j.cej.2016.11.095 ↗
11. Strontium doping into diopside tissue engineering scaffolds10.1016/j.ceramint.2019.02.067 ↗
12. Incorporation of monovalent cations into diopside to improve biomineralization and cytocompatibility10.1016/j.ceramint.2018.07.140 ↗
13. Enhanced sinterability and in vitro bioactivity of diopside through fluoride doping10.1016/j.ceramint.2016.12.144 ↗
14. 2004
15. 2017
16. 2008
17. 2010
18. Evaluation ofK Ic of brittle solids by the indentation method with low crack-to-indent ratios10.1007/BF00724706 ↗
19. Simulated body fluid and the novel bioactive materials derived from it10.1002/jbm.a.36620 ↗
20. Effect of sintering temperature on structural and morphological properties of europium (III) oxide doped willemite10.1155/2014/328931 ↗
21. Modified Scherrer equation to estimate more accurately nano-crystallite size using XRD10.4236/wjnse.2012.23020 ↗
22. An experimental investigation of extrapolation methods in the derivation of accurate unit-cell dimensions of crystals10.1088/0959-5309/57/3/302 ↗
23. Correlation between subgrains and coherently scattering domains10.1154/1.2135313 ↗
24. Bioactivity studies of calcium magnesium silicate prepared from eggshell waste by sol–gel combustion synthesis10.1016/j.jascer.2015.01.002 ↗
25. Preparation and cellular response of porous A-type carbonated hydroxyapatite nanoceramics10.1016/j.msec.2012.02.014 ↗
26. Influence of the non-bridging oxygen groups on the bioactivity of silicate glasses10.1023/A:1021174912802 ↗
27. Enhanced mechanical properties by grain boundary strengthening in ultra-fine-grained TZP ceramics10.1016/0955-2219(95)00181-6 ↗
28. A novel akermanite bioceramic: preparation and characteristics10.1177/0885328206057953 ↗
29. The effect of strontium incorporation into CaSiO3 ceramics on their physical and biological properties10.1016/j.biomaterials.2007.04.002 ↗
30. Effect of powder characteristics on the sinterability of hydroxyapatite powders10.1023/A:1008930313194 ↗
31. Bioceramics of calcium orthophosphates10.1016/j.biomaterials.2009.11.050 ↗
32. A novel MgO-CaO-SiO2 system for fabricating bone scaffolds with improved overall performance10.3390/ma9040287 ↗
33. Effect of fuel characteristics on synthesis of calcium hydroxyapatite by solution combustion route10.1007/s12034-010-0010-3 ↗
34. Correlation between properties and microstructure of laser sintered porous β-tricalcium phosphate bone scaffolds10.1088/1468-6996/14/5/055002 ↗
35. Synthetic bone graft substitutes10.1046/j.1440-1622.2001.02128.x ↗
36. Biphasic calcium phosphate nanocomposite porous scaffolds for load-bearing bone tissue engineering10.1016/j.biomaterials.2003.12.023 ↗
37. Hench · 2013 · [1]
38. Processing and properties of transparent hydroxyapatite and β tricalcium phosphate obtained by HIP process10.1016/j.ceramint.2012.06.023 ↗
39. Degradable biomaterials based on magnesium corrosion10.1016/j.cossms.2009.04.001 ↗
40. Morphological variation of hydroxyapatite grown in aqueous solution based on simulated body fluid10.1039/C1CE06114C ↗
41. Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic10.1016/j.biomaterials.2004.09.019 ↗
42. Morphology of apatite formed on surface of wollastonite coating soaked in simulate body fluid10.1016/S0167-577X(02)00848-0 ↗
43. Bioactive ceramic-based materials with designed reactivity for bone tissue regeneration10.1098/rsif.2008.0419.focus ↗
44. Formation and characteristics of the apatite layer on plasma-sprayed hydroxyapatite coatings in simulated body fluid10.1016/S0142-9612(97)00022-7 ↗
45. Research of calcium phosphates using Fourier transform infrared spectroscopy
46. Toward smart implant synthesis: bonding bioceramics of different resorbability to match bone growth rates10.1038/srep10677 ↗
47. Biosilicate scaffolds for bone regeneration: influence of introducing SrO10.1039/C7RA01606A ↗
48. The effect of calcium phosphate ceramic composition and structure on in vitro behavior. I. Dissolution10.1002/jbm.820270105 ↗
49. New strontium-based bioactive glasses: physicochemical reactivity and delivering capability of biologically active dissolution products10.1039/b822214b ↗