Improvement of thermomechanical properties of composite based on hydroxyapatite functionalized with alkylsilanes in epoxy matrix
Source abstract
Abstract
Abstract We synthesized composite materials (MCs) to be used as bone tissue replacement materials. The MCs were based on non-modified hydroxyapatite (HA), hydroxyapatite functionalized with 3-aminopropyltriethoxysilane (HAF), and epoxy resin (R-Epoxy). Superficial modification was performed using a chemical method under constant stirring and reflux for 24 h at 25 °C. Composites were obtained by loading R-Epoxy with 5% and 10% w/w HA and HAF, respectively. To analyze the effect of HA on the polymer chain and to evaluate its influence on the crystallinity and thermomechanical properties of the MCs, morphologic, thermal, and mechanical tests were used. Flexion, compression, traction, nanoindentation, thermogravimetric analysis, differential scanning calorimetry, scanning electron microscopy, X-ray diffraction, and Fourier-transform infrared analyses were performed. The results indicated that HA functionalization was achieved, which led to an improvement in the mechanical properties of the MCs. The mechanical properties of the MCs obtained by reinforcing R-Epoxy with 5–10% w/w HAF were significantly improved. Likewise, the functionalization of HA improved its dispersion in the R-Epoxy matrix. Moreover, the increase in the thermal stability of the MCs was attributed to the presence of HA.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · biodegradable polymer synthesis and properties · Additive Manufacturing and 3D Printing Technologies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (59)
Show source-provided references
1. Gamma irradiation of human bone allografts alters medullary lipids and releases toxic compounds for osteoblast-like cells10.1016/S0142-9612(99)00193-3 ↗
2. Review: mineralization of synthetic polymer scaffolds for bone tissue engineering10.1089/ten.2006.0394 ↗
3. Synthesis of hydroxyapatite for biomedical applications10.1016/j.cis.2017.04.007 ↗
4. Recent advances in bone tissue engineering scaffolds10.1016/j.tibtech.2012.07.005 ↗
5. Nano-hydroxyapatite composite biomaterials for bone tissue engineering - a review10.1166/jbn.2014.1893 ↗
6. Hydroxyapatite: preparation, properties and its biomedical applications10.4236/aces.2018.84016 ↗
7. Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering10.1016/j.biomaterials.2005.08.016 ↗
8. Hydroxyapatite nanocrystals for biomedical applications10.1021/jp106078b ↗
9. Water absorption characteristics of dental composites incorporating hydroxyapatite filler10.1016/S0142-9612(01)00331-3 ↗
10. Synthesis methods for nanosized hydroxyapatite with diverse structures10.1016/j.actbio.2013.04.012 ↗
11. Preparation and characterization of hydroxyapatite macrobeads based on pneumatic extrusion dripping10.1016/j.ceramint.2019.05.168 ↗
12. Novel hydroxyapatite-based bio-ceramic hollow fiber membrane derived from waste cow bone for textile wastewater treatment10.1016/j.cej.2019.122396 ↗
13. Evaluation of hot-pressed hydroxyapatite/poly-L-lactide composite biomaterial characteristics10.1002/jbm.b.30093 ↗
14. Growth and characterization of hydroxyapatite crystals by hydrothermal method10.1007/s10856-006-0070-5 ↗
15. Preparation of hydroxyapatite fibers by electrospinning technique10.1111/j.1151-2916.2004.tb06351.x ↗
16. Rapid formation of mono-dispersed hydroxyapatite nanorods with narrow-size distribution via microwave irradiation10.1111/j.1551-2916.2008.02690.x ↗
17. Surfactant-assisted preparation of fluoride-substituted hydroxyapatite nanorods10.1016/j.matlet.2005.05.019 ↗
18. Preparation of hydroxyapatite via microemulsion route10.1016/S0021-9797(02)00233-3 ↗
19. Extraction of pure natural hydroxyapatite from the bovine bones bio waste by three different methods10.1016/j.jmatprotec.2008.07.040 ↗
20. Analysis of a biodegradable composite for bone healing10.1002/(SICI)1097-4636(199611)32:3<419::AID-JBM15>3.0.CO;2-B ↗
21. Polymer-hydroxyapatite composites for biodegradable bone fillers10.1016/0142-9612(86)90099-2 ↗
22. The influence of polymer blend composition on the degradation of polymer/hydroxyapatite biomaterials10.1023/A:1011204106373 ↗
23. Preparation of bioactive porous HA/PCL composite scaffolds10.1016/j.apsusc.2008.08.056 ↗
24. Synthesis and application of hydroxyapatite/polylactide composite biomaterial10.1016/j.apsusc.2004.05.227 ↗
25. PLGA/nHA hybrid nanofiber scaffold as a nanocargo carrier of insulin for accelerating bone tissue regeneration10.1186/1556-276X-9-314 ↗
26. Ab initio modeling of protein/biomaterial interactions: Glycine adsorption at hydroxyapatite surfaces10.1021/ja806520d ↗
27. Synthesis and properties of hydroxyapatite/poly-L-lactide composite biomaterials10.1016/S0142-9612(98)00234-8 ↗
28. Hydroxyapatite-polyethylene composites for bone substitution: effects of ceramic particle size and morphology10.1016/S0142-9612(98)00154-9 ↗
29. In vitro evaluation of a new polymethylmethacrylate cement reinforced with hydroxyapatite10.1023/A:1008907218330 ↗
30. Hydroxyapatite and hydroxyapatite-based ceramics10.1023/A:1020585800572 ↗
31. Development and characterization of UV curable epoxy/hydroxyapatite suspensions for stereolithography applied to bone tissue engineering10.1016/j.ceramint.2014.06.117 ↗
32. Epoxy-based gelcasting of machinable hydroxyapatite foams for medical applications10.1111/jace.15523 ↗
33. Elements of light-cured epoxy-based dental polymer systems10.1177/00220345980770041301 ↗
34. Photocurable epoxy-polyol matrices for use in dental composites I10.1016/S0142-9612(00)00059-4 ↗
35. Reinforcing hydroxyapatite/thermosetting epoxy composite with 3-D carbon fiber fabric through RTM processing10.1016/S0167-577X(03)00437-3 ↗
36. Mechanical and thermal properties of hydroxyapatite-impregnated bone cement
37. Biological and mechanical properties of PMMA-based bioactive bone cements10.1016/S0142-9612(00)00097-1 ↗
38. Polymethylmethacrylate-based bone cement modified with hydroxyapatite10.1002/(SICI)1097-4636(1999)48:2<150::AID-JBM9>3.0.CO;2-D ↗
39. Flexural and fatigue properties of a bone cement based upon polyethylmethacrylate and hydroxyapatite10.1007/BF00134320 ↗
40. Influence of the concentration of copper nanoparticles on the thermo-mechanical and antibacterial properties of nanocomposites based on poly(butylene adipate- co -terephthalate)
41. Comparative study of the antimicrobial effect of nanocomposites and composite based on poly ( butylene adipate-co- terephthalate ) using Cu and Cu/Cu 2 O nanoparticles and CuSO 410.1186/s11671-019-2987-x ↗
42. Aminopropyltriethoxysilane (APTES)-functionalized nanoporous polymeric gratings: fabrication and application in biosensing10.1039/b711200a ↗
43. Preparation and characterisation of covalent polymer functionalized graphene oxide10.1039/C0JM01859G ↗
44. Enhancement of mechanical strength of TiO2/high-density polyethylene composites for bone repair with silane-coupling treatment10.1016/j.materresbull.2005.09.014 ↗
45. Characterization of silane-treated hydroxyapatite powders for use as filler in biodegradable composites10.1002/(SICI)1097-4636(199602)30:2<231::AID-JBM13>3.0.CO;2-P ↗
46. Bacteria-repulsive polyglycerol surfaces by grafting polymerization onto aminopropylated surfaces10.1021/la303541h ↗
47. Estimation of the surface interaction mechanism of ZnO nanoparticles modified with organosilane groups by Raman Spectroscopy10.1016/j.ceramint.2017.06.027 ↗
48. An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments10.1557/JMR.1992.1564 ↗
49. Understanding nanoindentation unloading curves10.1557/JMR.2002.0386 ↗
50. Properties of hydroxyapatite produced by annealing of bovine bone10.1016/j.ceramint.2006.04.001 ↗
51. Effect of the calcination temperature on the composition and microstructure of hydroxyapatite derived from human and animal bone10.1016/j.ceramint.2010.07.016 ↗
52. Carbonate hydroxyapatite functionalization: a comparative study towards (bio)molecules fixation10.1098/rsfs.2013.0040 ↗
53. Fresh and mechanical properties, and strain sensing of nanomodified cement mortars: the effects of MWCNT aspect ratio, density and functionalization10.1016/j.cemconcomp.2017.05.004 ↗
54. Improving the dispersion and flexural strength of multiwalled carbon nanotubes – stiff epoxy composites through b -hydroxyester surface functionalization coupled with the anionic homopolymerization of the epoxy matrix10.1016/j.eurpolymj.2006.04.016 ↗
55. Improved mechanical properties of carbon nanotube/polymer composites through the use of carboxyl-epoxide functional group linkages10.1016/j.polymer.2010.08.063 ↗
56. Reinforcing epoxy polymer composites through covalent integration of functionalized nanotubes10.1002/adfm.200305162 ↗
57. Various preparation methods of highly porous hydroxyapatite/polymer nanoscale biocomposites for bone regeneration10.1016/j.actbio.2011.07.002 ↗
58. Thermal properties, phase morphology and stability of biodegradable PLA/PBSL/HAp composites10.1016/j.polymdegradstab.2018.06.010 ↗
59. The effects of sintering on the properties of epoxy composites reinforced with chicken bone-based hydroxyapatites10.1016/j.polymertesting.2019.105987 ↗