Design of an Antibiotic Delivery System Based on a Bioresorbable Bone Substitute
Source abstract
Abstract
Abstract In the current study a new composite material comprising calcium sulphate, calcium carbonate, and tripalmitin was developed as a bioresorbable drug carrier for the local antibiotic therapy. Device fabrication can be simply performed by compression moulding of the components. The evaluated bone substitute material based on a calcium sulphate/calcium carbonate composite exhibits an excellent biocompatibility and a therapeutically useful release profile. It, therefore, represents a promising new antibiotic delivery system for the efficient prevention and treatment of bone infections.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Orthopedic Infections and Treatments · Endodontics and Root Canal Treatments
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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