The effect of iron incorporation on the in vitro bioactivity and drug release of mesoporous bioactive glasses
Source abstract
Abstract
Abstract Magnetic mesoporous bioactive glasses with the composition x Fe–(80− x )SiO 2 –15CaO–5P 2 O 5 (mol%) (Fe/MBGs) were prepared by the non-ionic block copolymer EO 20 PO 70 EO 20 (P123) surfactant as template and the evaporation-induced self-assembly process using Ca, P, Si and Fe sources. The structure, morphology and magnetic properties of Fe/MBGs were characterized by X-ray diffraction, scanning electron microscopy, infrared spectra, vibrating sample magnetometer and N 2 adsorption–desorption technique. The results show that Fe/MBGs have porous network (pore diameter of 50–100 nm), mesoporous walls (mesoporous size of 4–5 nm), and that the mesostructure, magnetic properties and in vitro bioactivity of the Fe/MBGs depend on the chemical composition. Furthermore, the Fe incorporation in the MBGs enhanced the magnetic properties, demonstrated sustained drug delivery and maintained apatite-formation ability in SBF. This means that the Fe/MBGs allowed bioactivity could improve their drug delivery capacity, thus enhancing their potential applications as bioactive filler materials for bone tissue regeneration.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Layered Double Hydroxides Synthesis and Applications · Calcium Carbonate Crystallization and Inhibition
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (24)
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