Examination of morphology, degradation and biocompatibility of fluorapatite–forsterite nanocomposite

Abstract This research has been done to study the characteristics and biocompatible evaluation of nano-biocomposite ceramic. Nanocomposites with the base of fluorapatite with 15, 25, 35 wt% of forsterite have been synthesized by the sol-gel method. Fluorapatite-forsterite nanocomposites have been characterized in terms of degradation by determining the weight change percentages and the pH changes in terms of bioactivity by checking the apatite layer formation using a solution of simulated body fluid (SBF). The release rate of silicon ions and fluorine ions are measured by ICP and fluorine selective electrode, respectively. This is the indication of desirable bioactivity in the synthesized nanocomposite and can be increased by adding the amount of forsterite in the samples and the higher solubility of the forsterite incompatible with fluorapatite. Compressive strength measurements indicate that the compressive strength of the nanocomposite increases by adding the forsterite percentages. The result of MTT assay indicates nontoxicity and decreases the cell viability in 7 days incompatible with the first day.