In vitro cellular response and hydrothermal aging of two-step sintered Nb2O5 doped ceria stabilized zirconia ceramics
Source abstract
Abstract
Abstract Niobia (1 mol. %) doped Ceria Stabilized Zirconia (NbCSZ) powders were synthesized using a co-precipitation method. The synthesized powders were uniaxially compacted and sintered in air. The two-step sintering method was adopted to sinter the samples, and the sintering schedule was optimized based on density, grain size, the phase present, and the hardness of the sintered sample. It was observed that the two-step sintering method effectively suppressed the grain growth of NbCSZ samples and helped in achieving a finer grain size of 1.57 μm along with the hardness of 1195 HV10 and optimum fracture toughness value 6.20 MPa m1/2. The Low-Temperature Degradation (LTD) behavior of the sintered samples was estimated through an accelerated hydrothermal aging test, which revealed that the samples are highly resistant to LTD and shown no phase change even after 150 h of study. Moreover, the cytocompatibility of the NbCSZ was tested by culturing MG63 cells on the samples for 7 days. The NbCSZ was found to be highly biocompatible as evident from cell viability and metabolic activity assay.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Advanced materials and composites · Dental materials and restorations
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (48)
Show source-provided references
1. Zirconia as a ceramic biomaterial10.1016/S0142-9612(98)00010-6 ↗
2. What future for zirconia as a biomaterial?10.1016/j.biomaterials.2005.07.034 ↗
3. Application of zirconia in dentistry : biological , mechanical and optical considerations
4. Fabrication and characterization of ZrO2 incorporated SiO2–CaO–P2O5 bioactive glass scaffolds10.1016/j.jmbbm.2020.103854 ↗
5. Bioceramics for hard tissue engineering applications: a Review
6. Phase analysis in zirconia systems10.1111/j.1151-2916.1972.tb11290.x ↗
7. Martensitic transformation in zirconia containing ceramics and its applications10.1016/j.cossms.2006.02.012 ↗
8. Martensitic transformation in zirconia10.1002/pssa.2210210102 ↗
9. CaO-containing tetragonal ZrO2 polycrystals (Ca-TZP)10.1016/0272-8842(87)90048-4 ↗
10. Study on the structure and mechanical properties of magnesia partially stabilized zirconia during cyclic heating and cooling10.1016/j.matlet.2017.01.135 ↗
11. Effect of agglomeration and calcination temperature on the mechanical properties of yttria stabilized zirconia (YSZ)10.1016/j.ceramint.2014.05.144 ↗
12. Strengthening of Ceria‐doped tetragonal zirconia polycrystals by reduction‐induced phase transformation10.1111/j.1151-2916.1989.tb06267.x ↗
13. Review-Transformation toughening in ceramics: martensitic transformations in crack-tip stress fields10.1111/j.1151-2916.1980.tb10712.x ↗
14. Low-temperature degradation of different zirconia ceramics for dental applications10.1016/j.actbio.2011.11.016 ↗
15. Low-temperature degradation of Y-TZP ceramics: a systematic review and meta-analysis10.1016/j.jmbbm.2015.10.017 ↗
16. Degradation during aging of transformation-toughened materials at 250 °C10.1111/j.1151-2916.1986.tb07415.x ↗
17. The tetragonal-monoclinic transformation in zirconia: lessons learned and future trends10.1111/j.1551-2916.2009.03278.x ↗
18. Role of H2O on the degradation process of Y-TZP10.1007/BF01756800 ↗
19. Tsukuma · 1983
20. Watanabe · 1983
21. Aging behavior of ceria‐stabilized tetragonal zirconia polycrystals10.1111/j.1151-2916.1988.tb05031.x ↗
22. Synthesis and sintering behaviour in CeO2 -ZrO2 ceramics10.1007/BF00547451 ↗
23. Strength , fracture toughness and Vickers hardness of CeO2-stabilized tetragonal10.1007/BF01026311 ↗
24. Mechanical properties and thermal stability of CeO2 containing tetragonal zirconia polycrystals
25. Influence of sintering parameters on tribological properties of ceria stabilized zirconia bio-ceramics10.1016/j.ceramint.2010.08.041 ↗
26. Effect of Nb2O5 on sintering and mechanical properties of ceria stabilized zirconia10.1016/j.jallcom.2018.06.280 ↗
27. Sintering, microstructure, hardness, and fracture toughness behavior of Y2O3‐CeO2‐ZrO210.1111/j.1151-2916.1988.tb07528.x ↗
28. Grain size control of tetragonal zirconia polycrystals using the space charge concept10.1111/j.1151-2916.1990.tb06449.x ↗
29. Sintering dense nanocrystalline ceramics without final-stage grain growth10.1038/35004548 ↗
30. Two-step sintering applied to ceramics10.5772/34112 ↗
31. Two-stage sintering of alumina with submicrometer grain size10.1111/j.1551-2916.2006.01408.x ↗
32. Effect of two-step sintering on the hydrothermal ageing resistance of tetragonal zirconia polycrystals10.1016/j.ceramint.2017.03.052 ↗
33. Two-step sintering of ceramics with constant grain-size, II: BaTiO3 and Ni-Cu-Zn ferrite10.1111/j.1551-2916.2005.00728.x ↗
34. Densification and grain growth of Gd2Zr2O7 nanoceramics during pressureless sintering10.1016/j.jeurceramsoc.2016.09.019 ↗
35. Astm B962-17 · 2017
36. A critical evaluation of indentation techniques for measuring fracture toughness: I, Direct Crack Measurements10.1111/j.1151-2916.1981.tb10320.x ↗
37. Low‐temperature aging of Y‐TZP ceramics10.1111/j.1151-2916.1999.tb02055.x ↗
38. 2015
39. Synthesis and characterization of nHA-PEG and nBG-PEG scaffolds for hard tissue engineering applications10.1016/j.ceramint.2019.01.145 ↗
40. Cytocompatibility evaluation of etched zirconia ceramics using human osteoblast-like MG 63 cells10.14815/kjdm.2016.43.4.331 ↗
41. In vitro cytocompatibility, ageing and wear behavior of ceria stabilized zirconia bioceramic10.1016/j.ceramint.2014.07.117 ↗
42. Transformation toughening - Part 1 Size effects associated with the thermodynamics of constrained transformations10.1007/BF00809057 ↗
43. Improvement of thermal stability of Yttria-doped tetragonal zirconia polycrystals by alloying with various oxides10.1016/0267-3762(86)90048-2 ↗
44. Effect of dopants on zirconia stabilization - an X-ray absorption study: II, Tetravalent Dopants10.1111/j.1151-2916.1994.tb05404.x ↗
45. Effect of calcia co-doping on ceria-stabilized zirconia10.1016/j.jeurceramsoc.2017.12.053 ↗
46. Biological evaluation of medical devices – Part 5. Tests for Cytotoxicity
47. Osteoblast response to zirconia surfaces with different topographies10.1016/j.msec.2015.07.052 ↗
48. Development and characterization of zirconia–alumina composites for orthopedic implants10.1016/j.ceramint.2016.09.216 ↗