journal article·2014-09

Porous HA microspheres as drug delivery: Effects of porosity and pore structure on drug loading and in vitro release

Min Yu, Kechao Zhou, Fuqiang Zhang, Dou Zhang

Ceramics International· Volume 40· Issue 8
Publisher page

Abstract

Abstract Porous hydroxyapatite (HA) microspheres with the main particle size of 42–50 μm were fabricated using a novel ITSD technique. Pore structures transformed from aligned pores to cellular pores, with the increase of PVA contents. The percentages of GS loadings decreased from 41.8% to 30.9%, with porosities decreasing from 58.7% to 40.2%. Gentamicin was successfully loaded into porous HA microspheres and about 80% of loaded-GS amount was released from GS-loaded HA microspheres during 48 h period.
Source: openaire · Quality: candidate unverified · Source record ↗

Research context

OpenAlex topics: Bone Tissue Engineering Materials · Layered Double Hydroxides Synthesis and Applications · biodegradable polymer synthesis and properties

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

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