Zinc-releasing calcium phosphate cements for bone substitute materials
Source abstract
Abstract
The goal of the present study was to develop zinc-doped calcium phosphate bone cements (CPCs-Zn) for functionalized bone grafts applications. An aqueous co-precipitation process for synthesis of ?-tricalcium phosphate (?-TCP) powder samples with Zn addition ranging from 0. wt% up to 1.2. wt% was proposed as an alternative approach to produce CPCs-Zn, instead of mechanical mixing of powders. Real-time monitoring of structural transformations and kinetics of CPCs-Zn (Zn=0. wt%, 0.6. wt% and 1.2. wt%) was carried out by the Energy Dispersive X-Ray Diffraction technique. The microstructure development in CPCs-Zn was investigated by Scanning Electron Microscopy. Zn-ion release from CPC-Zn 0.6. wt% and CPC-Zn 1.2. wt% cements, measured by the Atomic Emission Spectroscopy, corresponded to the average values of 0.30±0.01 and 0.10±0.01. ?g/L, respectively. The results of antibacterial tests proved the inhibitory effect towards pathogenic . Escherichia coli only for the CPC-Zn 0.6. wt% cement formulation.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental materials and restorations · Dental Implant Techniques and Outcomes
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (21)
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