Bioactive, luminescent erbium-doped hydroxyapatite nanocrystals for biomedical applications
Source abstract
Abstract
Abstract Diagnosis and imaging play an essential key role in primary detection, screening, and image-guided smart nanomedicine for healthcare solutions. This study illustrates the successful fabrication of luminescent lanthanide (erbium)-doped hydroxyapatite (Er-HAp) by one step facile wet-chemical precipitation method. The chemical compositions, morphology, optical, and biological properties were systematically characterized using relevant different structural, compositional analytical instrumentation and cytotoxicity assays. After erbium doping, synthesized luminescent nano-structured materials exhibited elongated morphology, with well dispersed
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Luminescence Properties of Advanced Materials · Bone Tissue Engineering Materials · Nanoplatforms for cancer theranostics
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (47)
Show source-provided references
1. Upconversion nanoparticles: design, nanochemistry, and applications in theranostics10.1021/cr400425h ↗
2. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells10.1021/nl052396o ↗
3. Imaging intracellular fluorescent proteins at nanometer resolution10.1126/science.1127344 ↗
4. Multifunctional inorganic nanoparticles for imaging, targeting, and drug delivery10.1021/nn800072t ↗
5. Water-soluble quantum dots for multiphoton fluorescence imaging in vivo10.1126/science.1083780 ↗
6. Fluorine-18-labeled Gd3+/Yb3+/Er3+ co-doped NaYF4 nanophosphors for multimodality PET/MR/UCL imaging10.1016/j.biomaterials.2010.09.071 ↗
7. Recent advances in the chemistry of lanthanide-doped upconversion nanocrystals10.1039/b809132n ↗
8. Multifunctional nanoprobes for upconversion fluorescence, MR and CT trimodal imaging10.1016/j.biomaterials.2011.10.039 ↗
9. Combined optical and MR bioimaging using rare earth ion doped NaYF4 nanocrystals10.1002/adfm.200800765 ↗
10. Fluorine-18 labeled rare-earth nanoparticles for positron emission tomography (PET) imaging of sentinel lymph node10.1016/j.biomaterials.2011.01.011 ↗
11. Hydrothermal synthesis of NaLuF4: 153Sm, Yb, Tm nanoparticles and their application in dual-modality upconversion luminescence and SPECT bioimaging10.1016/j.biomaterials.2012.10.022 ↗
12. Facile preparation of multifunctional upconversion nanoprobes for multimodal imaging and dual‐targeted photothermal therapy10.1002/anie.201101447 ↗
13. In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers10.1038/nm.2933 ↗
14. Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles10.1016/j.biomaterials.2011.05.007 ↗
15. Photon conversion in lanthanide-doped powder phosphors: concepts and applications10.1039/C4RA15804K ↗
16. Recent progress on fabrication and drug delivery applications of nanostructured hydroxyapatite
17. Optimized Zn-doped hydroxyapatite/doxorubicin bioceramics system for efficient drug delivery and tissue engineering application10.1016/j.ceramint.2017.12.235 ↗
18. Rapid microwave-assisted synthesis of gold loaded hydroxyapatite collagen nano-bio materials for drug delivery and tissue engineering application10.1016/j.ceramint.2018.10.016 ↗
19. Structural characterization, optical properties and in vitro bioactivity of mesoporous erbium-doped hydroxyapatite10.1016/j.jallcom.2015.05.064 ↗
20. Na-doped hydroxyapatite coating on carbon/carbon composites: preparation, in vitro bioactivity and biocompatibility10.1016/j.apsusc.2012.09.022 ↗
21. Copper substituted hydroxyapatite and fluorapatite: synthesis, characterization and antimicrobial properties10.1016/j.ceramint.2014.07.086 ↗
22. Oxidative dehydrogenation of propane over chromium-loaded calcium-hydroxyapatite10.1016/j.apcata.2009.01.005 ↗
23. Development and characterization of titanium-containing hydroxyapatite for medical applications10.1016/j.actbio.2009.06.032 ↗
24. Cationic substitutions in hydroxyapatite: current status of the derived biofunctional effects and their in vitro interrogation methods
25. Biomimetic synthesis of metal–hydroxyapatite (Au-HAp, Ag-HAp, Au-Ag-HAp): structural analysis, spectroscopic characterization and biomedical application10.1016/j.ceramint.2018.08.045 ↗
26. Characterization, physicochemical properties and biocompatibility of La-incorporated apatites10.1016/j.actbio.2009.05.026 ↗
27. Preparation, characterization and antibacterial property of cerium substituted hydroxyapatite nanoparticles10.1016/S1002-0721(07)60455-4 ↗
28. Enhancement of luminescence efficiency of f–f transitions from Tb3+ due to energy transfer from Ce3+ in Al2O3 crystalline ceramic powders prepared by low temperature direct combustion synthesis10.1016/j.cplett.2004.11.015 ↗
29. The photoluminescence, drug delivery and imaging properties of multifunctional Eu3+/Gd3+ dual-doped hydroxyapatite nanorods10.1016/j.biomaterials.2011.08.032 ↗
30. Luminomagnetic Eu3+-and Dy3+-doped hydroxyapatite for multimodal imaging10.1016/j.msec.2017.08.032 ↗
31. Synthesis and characterization of neodymium (III) and gadolinium (III)‐Substituted hydroxyapatite as biomaterials10.1111/j.1744-7402.2008.02293.x ↗
32. Surface modification of hydroxyapatite nanocrystallite by a small amount of terbium provides a biocompatible fluorescent probe10.1021/jp8026463 ↗
33. 175Yb-labeled hydroxyapatite: a potential agent for use in radiation synovectomy of small joints10.1016/j.nucmedbio.2006.02.004 ↗
34. 166Ho-labeled hydroxyapatite particles: a possible agent for liver cancer therapy
35. Accumulation of rare earth elements in human bone within the lifespan10.1039/C0MT00069H ↗
36. A novel 1540 nm light emission from erbium doped hydroxyapatite/β-tricalcium phosphate through co-precipitation method10.1016/j.matlet.2016.01.002 ↗
37. Natural origin hydroxyapatite scaffold as potential bone tissue engineering substitute10.1016/j.ceramint.2016.08.165 ↗
38. New core-shell hydroxyapatite/Gum-Acacia nanocomposites for drug delivery and tissue engineering applications10.1016/j.msec.2018.07.018 ↗
39. Low temperature wet-chemical synthesis of spherical hydroxyapatite nanoparticles and their in situ cytotoxicity study10.12989/anr.2016.4.4.295 ↗
40. Europium concentration effect of europium doped hydroxyapatite on proliferation of osteoblast cells
41. Concentration dependent luminescence quenching of Er3+-doped zinc boro-tellurite glass10.1016/j.jlumin.2013.06.050 ↗
42. Nanostructured hollow hydroxyapatite fabrication by carbon templating for enhanced drug delivery and biomedical applications10.1016/j.ceramint.2019.05.260 ↗
43. Effects of temperature on the preparation and characteristics of hydroxyapatite and its adsorptive properties toward lead10.1039/C4NJ01836B ↗
44. Ion exchange in hydroxyapatite with lanthanides10.1021/ic502425e ↗
45. Overview of hydroxyapatite–graphene nanoplatelets composite as bone graft substitute: mechanical behavior and in-vitro biofunctionality10.1080/10408436.2017.1333951 ↗
46. Hydroxyl-quenching effects on the photoluminescence properties of SnO2: Eu3+ nanoparticles10.1021/jp067217l ↗
47. Concentration dependence of the Er 3+ visible and infrared luminescence in Y 2− x Er x O 3 thin films on Si10.1063/1.3195077 ↗