Synthesis and characterization of hydroxyapatite/carboxylic acid functionalized MWCNTS composites and its triple layer coatings for biomedical applications
Source abstract
Abstract
Abstract Introduction Achievement of bioactive coatings on metallic implant surface with higher adhesive strength and corrosive resistance was one of the main challenges for the current biomaterial researchers. Hydroxyapatite was one of the promising bioactive ceramic which can be applied as a coating on the metallic substrate due to its similarity with the human bone. Methods The work describes the in-situ preparation of HAP/ f -MWCNTs composite by sol-gel method. MWCNTs were functionalized by acid treatment. HAP composites have been prepared by varying the molar percentage of f -MWCNTs from 1% to 5%. The prepared composites with various concentrations of f -MWCNTs were characterized by FT-IR and XRD for its functional group analysis and phase purity. The morphology of the prepared powder was analyzed using SEM and TEM. In-vitro corrosive behavior on SBF was studied for the coating prepared HAP composite sol on 316L SS. The triple layer composite coating was obtained at the spin speed of 3000 rpm/min and subjected to sintering at 500 °C/2 h. Results X-ray diffraction results confirmed the formation of pure HAP up to the addition of 3% of f -MWCNTs without any secondary phases. The average crystallite size of the prepared particles was decreased from 40 ± 2.1 to 17 ± 2.5 nm with the addition f -MWCNTs. The morphological studies confirm the incorporation of f -MWCNTs in HAP matrix. The prepared HAP/ f -MWCNTs composite efficiently inhibits the growth of the pathogens such as S. Aureus and E.coli . Improved hardness was observed with reinforcement of f -MWCNTs into the hydroxyapatite matrix. Electrochemical studies confirm the HAP/ f -MWCNTs composites having increased corrosive resistance properties. The bonding strength of the composite coatings showed improved adhesion to the 316L surface. Conclusion In this work we have fabricated sol-gel derived anti-microbial composite coating on the 316L substrate by means of spin coating at optimized conditions with higher adhesive strength and improved corrosion resistance.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Orthopaedic implants and arthroplasty · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (46)
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1. Preparation and characterization of sol–gel hydroxyapatite and its electrochemical evaluation for biomedical applications10.1002/jbm.a.31773 ↗
2. Influence of process parameters on the sol–gel synthesis of nano hydroxyapatite using various phosphorus precursors10.1007/s10971-012-2762-2 ↗
3. Influence of calcium precursors on the morphology and crystallinity of sol–gel-derived hydroxyapatite nanoparticles10.1016/j.jcrysgro.2008.07.118 ↗
4. Snail shell derived natural hydroxyapatite: effects on NIH-3T3 cells for orthopedic applications10.1080/10426914.2015.1070415 ↗
5. MG63 osteoblast cell response on Zn doped hydroxyapatite (HAp) with various surface features10.1016/j.ceramint.2016.12.010 ↗
6. Synthesis and characterization of silver doped hydroxyapatite nanocomposite coatings and evaluation of their antibacterial and corrosion resistance properties in simulated body fluid10.1016/j.msec.2016.07.057 ↗
7. Mechanical properties and biocompatibility of the sputtered Ti doped hydroxyapatite10.1016/j.jmbbm.2016.06.025 ↗
8. Deposition of nanostructured fluorine-doped hydroxyapatite– polycaprolactone duplex coating to enhance the mechanical properties and corrosion resistance of Mg alloy for biomedical applications10.1016/j.msec.2015.11.057 ↗
9. Innovative hydroxyapatite/bioactive glass composites processed by spark plasma sintering for bone tissue repair10.1016/j.jeurceramsoc.2016.11.012 ↗
10. A novel silica nanotube reinforced ionic incorporated hydroxyapatite composite coating on polypyrrole coated 316L SS for implant application10.1016/j.msec.2015.10.045 ↗
11. Hydroxyapatite–titania nanotube composite as a coating layer on Co–Cr-based implants: mechanical and electrochemical optimization10.1016/j.ceramint.2016.01.080 ↗
12. Preparation and characterization of novel sol-gel derived hydroxyapatite/ Fe3O4 composites coatings on Ti-6Al-4V for biomedical applications10.1016/j.matlet.2016.11.078 ↗
13. Preparation and characterization of a novel degradable nano-hydroxyapatite/poly(lactic-co-glycolic) composite reinforced with bamboo fiber10.1016/j.msec.2017.03.046 ↗
14. In situ synthesis and characterization of hydroxyapatite/natural rubber composites for biomedical applications10.1016/j.msec.2017.03.301 ↗
15. Improvement of mechanical and thermal properties of high energy electron beam irradiated HDPE/hydroxyapatite nano-composite10.1016/j.radphyschem.2016.09.002 ↗
16. Preparation and characterization of sol-gel derived Ce4+ doped hydroxyapatite and its in vitro biological evaluations for orthopedic applications10.1016/j.matdes.2017.01.095 ↗
17. Effect of carbon nanotube addition on friction coefficient of nanotubes/hydroxyapatite composites10.1016/j.jiec.2013.04.040 ↗
18. Hydroxyapatite grafted carbon nanotubes and graphene nanosheets: promising bone implant materials10.1016/j.saa.2014.04.004 ↗
19. Improved properties of hydroxyapatite–carbon nanotube biocomposite: mechanical, in vitro bioactivity and biological studies10.1016/j.ceramint.2013.10.158 ↗
20. Mechanical and in-vitro performance of CNT reinforced hydroxyapatite prepared by a shear mixing method10.4172/2157-7439.1000169 ↗
21. Influence of ionic substitution in improving the biological property of carbon nanotubes reinforced hydroxyapatite composite coating on titanium for orthopedic applications10.1016/j.ceramint.2014.12.114 ↗
22. Carbon nanotube reinforced hydroxyapatite composite for orthopedic application: a review10.1016/j.msec.2012.05.010 ↗
23. A novel sol–gel technique for hydroxyapatite preparation10.1016/S0254-0584(02)00392-9 ↗
24. In vitro characterization of polyvinyl alcohol assisted hydroxyapatite derived by sol–gel method10.1016/j.msec.2013.11.001 ↗
25. Sol–gel derived alumina–hydroxyapatite–tricalcium phosphate porous composite powders10.1016/j.ceramint.2011.11.032 ↗
26. Sol-gel derived porous and hydrophilic calcium hydroxyapatite coating on modified titanium substrate10.1016/j.surfcoat.2016.10.032 ↗
27. Biocompatibility of sol-gel hydroxyapatite-titania composite and bilayer coatings10.1016/j.msec.2016.11.129 ↗
28. Effect of functionalisation of CNT in the preparation of HAp–CNT biocomposites10.1016/j.ceramint.2014.11.052 ↗
29. Single-walled carbon nanotubes/hydroxyapatite coatings on titanium obtained by electrochemical deposition10.1016/j.apsusc.2014.01.009 ↗
30. Improvement of the fracture toughness of hydroxyapatite (HAp) by incorporation of carboxyl functionalized single walled carbon nanotubes(CfSWCNTs) and nylon10.1016/j.msec.2015.11.030 ↗
31. Development of functionalized carbon nanotube reinforced hydroxyapatite magnetic nanocomposites10.1016/j.matlet.2016.01.060 ↗
32. The functionalization of multi-walled carbon nanotubes by in situ deposition of hydroxyapatite10.1016/j.biomaterials.2010.03.012 ↗
33. Synthesis and characterization of hydroxyapatite nanocrystal and gelatin doped with Zn2+ and cross linked by glutaraldehyde
34. Inexpensive sol-gel synthesis of multiwalled carbon nanotube-TiO2 hybrids for high performance antibacterial materials10.1016/j.msec.2016.07.036 ↗
35. Broad-spectrum antibacterial activity of carbonnanotubes to human gut bacteria10.1002/smll.201202792 ↗
36. Antimicrobial activity of chitosan-carbon nanotube hydrogels10.3390/ma7053946 ↗
37. Development of carbon nanotubes reinforced hydroxyapatite composite coatings on titanium by electrodeposition method10.1016/j.corsci.2013.04.021 ↗
38. Hydroxyapatite coating containing multi-walled carbon nanotubes on AZ31 magnesium: mechanical-electrochemical degradation in a physiological environment10.1016/j.ceramint.2018.02.015 ↗
39. Mechanical and in vitro biological performances of hydroxyapatite–carbon nanotube composite coatings deposited on Ti by aerosol deposition10.1016/j.actbio.2009.05.005 ↗
40. Functionally graded carbon nanotubes/hydroxyapatite composite coating by laser cladding10.1016/j.surfcoat.2011.03.036 ↗
41. Preparation and properties of in-situ growth of carbon nanotubes reinforced hydroxyapatite coating for carbon/carbon composites10.1016/j.msec.2016.09.060 ↗
42. Graphene oxide/hydroxyapatite composite coatings fabricated by electrochemical deposition10.1016/j.surfcoat.2015.12.013 ↗
43. Graphene-based antibacterial composite coatings electrodeposited on titanium for biomedical applications10.1016/j.porgcoat.2015.01.019 ↗
44. Bioactive hydroxyapatite/graphene composite coating and its corrosion stability in simulated body fluid10.1016/j.jallcom.2014.11.078 ↗
45. Electrophoretic deposition of hydroxyapatite-chitosan-CNTs nanocomposite coatings10.1016/j.ceramint.2016.12.139 ↗
46. Graphene oxide/hydroxyapatite composite coatings fabricated by electrophoretic nanotechnology for biological applications10.1016/j.carbon.2013.09.080 ↗