Hydroxyapatite-based nanoparticles as a coating material for the dentine surface: An antibacterial and toxicological effect
Source abstract
Abstract
Abstract In this study, nano sized hydroxyapatite (nHAp) and Ag(I) doped hydroxyapatite (Ag-nHAp) particles were synthesized by the precipitation method and used as a coating material for remineralization on caries-affected dentine samples. Characterization studies of both the synthesized hydroxyapatite-based particles and the coated dentine samples were performed using instrumental techniques such as SEM and FTIR, and then toxicity and antibacterial properties were also evaluated. It was observed that dentine samples were effectively coated by both nHAp and Ag-nHAp particles which have no toxic effects. Furthermore, the coating of nano-hydroxyapatite on dentine samples positively contributed to the viability of L929 fibroblast cells and also provided an antibacterial effect against to bacteria such as S. mutants, C. albicans and E. coli bacteria that are most frequently caused caries in the teeth. While all type of bacteria was eliminated by the nHAp coated dentine samples at 24th, Ag-nHAp coated dentine samples removed to all bacteria type at 1st.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Dental Erosion and Treatment · Dental materials and restorations · Dental Anxiety and Anesthesia Techniques
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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