Porous hydroxyapatite ceramics by ice templating: Freezing characteristics and mechanical properties
Source abstract
Abstract
Abstract Ice templating produces porous hydroxyapatite (HA) scaffolds with a lamellar morphology and aligned channels when using aqueous HA slurries. We investigated the freezing characteristics of HA slurries with regard to the pore structures of the porous HA scaffolds. We found that by increasing the cooling rate, the lamellar spacing decreased. The average lamellar spacing is about 785.7 μm at a cooling rate of 1.3 °C/min. The porous geometry changes from lamella and well aligned channels to a partial dendrite and partially aligned cavities with a decrease in the initial nucleation temperature and an increase in the degree of supercooling. Additionally, we determined the relationship between compressive strength and porosity. The compressive strength of the porous HA scaffolds reach 6.7 MPa at a porosity of 64% and the lamellar spacing is about 124 μm.
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Research context
OpenAlex topics: Bone Tissue Engineering Materials · Additive Manufacturing and 3D Printing Technologies · Calcium Carbonate Crystallization and Inhibition
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (22)
Show source-provided references
1. Plasma-sprayed hydroxyapatite+titania composite bond coat for hydroxyapatite coating on titanium substrate10.1016/j.biomaterials.2003.10.092 ↗
2. Manufacture of hydroxyapatite beads for medical applications10.1016/j.jeurceramsoc.2008.06.008 ↗
3. Preparation and bioactivity evaluation of bone-like hydroxyapatite nanopowder10.1016/j.jmatprotec.2007.10.004 ↗
4. Mechanical behaviour of porous hydroxyapatite10.1016/j.actbio.2007.11.002 ↗
5. Preparation and characterization of porous hydroxyapatite through polymeric sponge method10.1016/j.ceramint.2009.05.012 ↗
6. Fabrication of functionally graded and aligned porosity in thin ceramic substrates with the novel freeze-tape-casting process10.1111/j.1551-2916.2007.01720.x ↗
7. Biological and physico-chemical assessment of hydroxyapatite (HA) with different porosity10.1016/j.bioeng.2007.08.015 ↗
8. Preparation of porous hydroxyapatite scaffolds by combination of the gel-casting and polymer sponge methods10.1016/S0142-9612(03)00171-6 ↗
9. Biocompatibility and osteogenesis of biomimetic nano-hydroxyapatite/polyamide composite scaffolds for bone tissue engineering10.1016/j.biomaterials.2007.04.014 ↗
10. Porous hydroxyapatite/gelatine scaffolds with ice-designed channel-like porosity for biomedical applications10.1016/j.actbio.2008.05.023 ↗
11. Improved compressive strength of reticulated porous zirconia using carbon coated polymeric sponge as novel template10.1016/j.matlet.2006.01.031 ↗
12. Thermal conductivity of porous alumina ceramics prepared using starch as a pore-forming agent10.1016/j.jeurceramsoc.2008.06.018 ↗
13. A modified model for alumina membranes formed by gel-casting followed by dip-coating10.1016/j.jeurceramsoc.2004.01.007 ↗
14. Freeze casting of hydroxyapatite scaffolds for bone tissue engineering10.1016/j.biomaterials.2006.06.028 ↗
15. Control of pore structure and mechanical property in hydroxyapatite/collagen composite using unidirectional ice growth10.1016/j.matlet.2005.10.064 ↗
16. Effects of gelatin addition on the microstructure of freeze-cast porous hydroxyapatite ceramics10.1016/j.ceramint.2008.11.022 ↗
17. Architectural control of freeze-cast ceramics through additives and templating10.1111/j.1551-2916.2009.03087.x ↗
18. The effect of polyvinyl alcohol on the microstructure and permeability of freeze-cast alumina10.1111/j.1551-2916.2009.03398.x ↗
19. Freezing as a path to build complex composites10.1126/science.1120937 ↗
20. In situ fabrication of porous hydroxyapatite (HA) scaffolds with dense shells by freezing HA/camphene slurry10.1016/j.matlet.2007.09.063 ↗
21. Mechanical properties of porous materials10.1023/A:1009669730778 ↗
22. Biomaterial developments for bone tissue engineering10.1016/S0142-9612(00)00102-2 ↗