Research progress on magnetic nanoparticles for magnetic induction hyperthermia of malignant tumor
Source abstract
Abstract
Abstract As a new malignant tumor therapy method with low side effect, high safety and efficiency, magnetic induction hyperthermia (MIH) has attracted great attention in recent years. As magnetic induction heating media, magnetic nanoparticles (MNPs) are critical for the development of MIH. For clinical safety, the MNPs need a high heating efficiency to reduce the applied dose, minimizing the risk of side effect. Increasing the saturation magnetization and initial susceptibility, adjusting the magnetocrystalline anisotropy constant and particle size to the optimal values are the effective methods of improving heating efficiency. On the other hand, a suitable Curie temperature is desired to realize the self-regulation of the therapy temperature, avoiding the use of clumsy and expensive temperature monitoring and control devices. Substituting the magnetic ions in tetrahedral (A) site of the spinel ferrite with nonmagnetic ions or magnetic ions with smaller magnetic moments can effectively reduce the superexchange interaction between the A and B (octahedral) sites, decreasing Curie temperature. Yet, the reduction of the Curie temperature by ion doping usually reduces the saturation magnetization, decreasing heating efficiency. Increasing the fraction of heat generated by relaxation loss and increasing the saturation magnetization may be used to improve the heating efficiency.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Characterization and Applications of Magnetic Nanoparticles · Nanoparticle-Based Drug Delivery · Nanopore and Nanochannel Transport Studies
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries, CA10.3322/caac.21492 ↗
2. Cancer statistics, 2020, CA10.3322/caac.21590 ↗
3. Selective inductive heating of lymph nodes10.1097/00000658-195710000-00007 ↗
4. Thermosensitive magnetic nanoparticles for self-controlled hyperthermia cancer treatment10.4172/2157-7439.1000e112 ↗
5. Intracellular hyperthermia a biophysical approach to cancer treatment via intracellular temperature and biophysical alterations10.1016/0306-9877(79)90063-X ↗
6. Magnetic nanoparticle-based therapeutic agents for thermo-chemotherapy treatment of cancer10.1039/C4NR03482A ↗
7. Cancer hyperthermia using magnetic nanoparticles10.1002/biot.201100045 ↗
8. Structural, thermal, spectral, optical and surface analysis of rare earth metal ion (Gd3+) doped mixed Zn–Mg nano-spinel ferrites10.1016/j.ceramint.2020.02.091 ↗
9. Influential diamagnetic magnesium (Mg2+) ion substitution in nano-spinel zinc ferrite (ZnFe2O4): thermal, structural, spectral, optical and physisorption analysis10.1016/j.ceramint.2019.12.097 ↗
10. Thermotherapy of prostate cancer using magnetic nanoparticles: feasibility, imaging, and three-dimensional temperature distribution10.1016/j.eururo.2006.11.023 ↗
11. Morbidity and quality of life during thermotherapy using magnetic nanoparticles in locally recurrent prostate cancer: results of a prospective phase I trial10.1080/02656730601175479 ↗
12. Efficacy and safety of intratumoral thermotherapy using magnetic iron-oxide nanoparticles combined with external beam radiotherapy on patients with recurrent glioblastoma multiforme10.1007/s11060-010-0389-0 ↗
13. Combined intracavitary thermotherapy with iron oxide nanoparticles and radiotherapy as local treatment modality in recurrent glioblastoma patients10.1007/s11060-018-03005-x ↗
14. Antitumor immunity by magnetic nanoparticle-mediated hyperthermia10.2217/nnm.14.106 ↗
15. Proposed use of self-regulating temperature nanoparticles for cancer therapy10.1080/14737140.2018.1483242 ↗
16. Physics responsible for heating efficiency and self-controlled temperature rise of magnetic nanoparticles in magnetic hyperthermia therapy10.1016/j.pbiomolbio.2017.10.001 ↗
17. Physical mechanism and modeling of heat generation and transfer in magnetic fluid hyperthermia through Néelian and Brownian relaxation: a review10.1186/s12938-017-0327-x ↗
18. Recent progress on magnetic nanoparticles for magnetic hyperthermia10.1007/s40204-016-0054-6 ↗
19. Inductive heating of ferrimagnetic particles and magnetic fluids: physical evaluation of their potential for hyperthermia10.3109/02656739309061478 ↗
20. Cellular uptake of magnetic fluid particles and their effects on human adenocarcinoma cells exposed to AC magnetic fields in vitro10.3109/02656739609027678 ↗
21. Effects of magnetic fluid hyperthermia (MFH) on C3H mammary carcinoma in vivo10.3109/02656739709023559 ↗
22. Magnetic fluid hyperthermia (MFH): cancer treatment with AC magnetic field induced excitation of biocompatible superparamagnetic nanoparticles10.1016/S0304-8853(99)00088-8 ↗
23. Thermal ablation of tumors using magnetic nanoparticles: an in vivo feasibility study10.1097/00004424-200210000-00008 ↗
24. Thermotherapy using magnetic nanoparticles combined with external radiation in an orthotopic rat model of prostate cancer10.1002/pros.20324 ↗
25. Nanosized As2O3/Fe2O3 complexes combined with magnetic fluid hyperthermia selectively target liver cancer cells10.3748/wjg.15.2995 ↗
26. Effects of magnetic fluid hyperthermia induced by an alternative magnetic field on human carcinoma A549 cell in vitro
27. High therapeutic efficiency of magnetic hyperthermia in xenograft models achieved with moderate temperature dosages in the tumor area10.1007/s11095-014-1417-0 ↗
28. Recent advances in magnetic fluid hyperthermia for cancer therapy10.1016/j.colsurfb.2018.10.051 ↗
29. Self-heating evaluation of superparamagnetic MnFe2O4 nanoparticles for magnetic fluid hyperthermia application towards cancer treatment10.1016/j.ceramint.2020.07.029 ↗
30. Effects of Mn concentration on the ac magnetically induced heating characteristics of superparamagnetic MnxZn1−xFe2O4 nanoparticles for hyperthermia10.1063/1.3430043 ↗
31. Magnetite ferrofluid with high specific absorption rate for application in hyperthermia10.1016/j.jmmm.2006.11.179 ↗
32. Cobalt doped magnetite nanoparticles: synthesis, characterization, optimization and suitability evaluations for magnetic hyperthermia applications10.1016/j.physe.2019.113759 ↗
33. Co-precipitation synthesis of (Zn-Mn)-co-doped magnetite nanoparticles and their application in magnetic hyperthermia10.1016/j.jallcom.2018.11.280 ↗
34. Studying the effect of Zn-substitution on the magnetic and hyperthermic properties of cobalt ferrite nanoparticles10.1039/C6NR01303A ↗
35. Ultrathin surface coated water-soluble cobalt ferrite nanoparticles with high magnetic heating efficiency and rapid in vivo clearance10.1016/j.biomaterials.2019.119655 ↗
36. Superparamagnetic MFe2O4 (M=Ni, Co, Zn, Mn) nanoparticles: synthesis, characterization, induction heating and cell viability studies for cancer hyperthermia applications10.1007/s10856-015-5466-7 ↗
37. Preparation and investigation of potentiality of different soft ferrites for hyperthermia applications10.1063/1.1855131 ↗
38. Study of AC magnetic heating characteristics of Co0.5Zn0.5Fe2O4 nanoparticles for magnetic hyperthermia therapy10.1016/j.jmmm.2013.08.039 ↗
39. Size-dependant heating rates of iron oxide nanoparticles for magnetic fluid hyperthermia10.1016/j.jmmm.2008.12.017 ↗
40. Size-dependent heating of magnetic iron oxide nanoparticles10.1021/acsnano.7b01762 ↗
41. Synthesis of exchange coupled nanoflowers for efficient magnetic hyperthermia10.1016/j.jmmm.2019.04.056 ↗
42. Exchange-coupled magnetic nanoparticles for efficient heat induction10.1038/nnano.2011.95 ↗
43. Nanoscale magnetism control via surface and exchange anisotropy for optimized ferrimagnetic hysteresis10.1021/nl301499u ↗
44. Water-soluble iron oxide nanocubes with high values of specific absorption rate for cancer cell hyperthermia treatment10.1021/nn2048137 ↗
45. Magnetic nanoparticles in MR imaging and drug delivery10.1016/j.addr.2008.03.018 ↗
46. Improving the magnetic heating by disaggregating nanoparticles10.1016/j.jallcom.2015.10.285 ↗
47. Magnetic particle hyperthermia—a promising tumour therapy10.1088/0957-4484/25/45/452001 ↗
48. Size dependence of specific power absorption of Fe3O4 particles in AC magnetic field10.1016/S0304-8853(03)00426-8 ↗
49. Tuning the magnetic properties of nanoparticles10.3390/ijms140815977 ↗
50. Specific absorption rate in Zn-doted ferrites for self-controlled magnetic hyperthermia10.1140/epjb/e2019-90567-2 ↗
51. Applications of magnetic nanoparticles in biomedicine10.1088/0022-3727/36/13/201 ↗
52. Magnetic nanoparticle design for medical diagnosis and therapy10.1039/b402025a ↗
53. Shape tailored magnetic nanorings for intracellular hyperthermia cancer therapy
54. Temperature dependence of magnetic anisotropy in nanoparticles of CoxFe3−xO410.1016/j.jmmm.2007.08.009 ↗
55. Correlation between magnetic properties and cationic distribution of Zn0.85−xNixMg0.05Cu0.1Fe2O4 nano spinel ferrite: effect of Ni doping10.1007/s10853-016-0636-7 ↗
56. Cation distribution in Zn–Cr spinel structure and its effects on synthesis of isobutanol from syngas: structure–activity relationship10.1016/j.molcata.2015.04.019 ↗
57. Effects of cation distribution on magnetic properties in cobalt ferrite10.1007/BF00455632 ↗
58. Comparative evaluation of heating ability and biocompatibility of different ferrite-based magnetic fluids for hyperthermia application10.1002/jbm.b.30630 ↗
59. Hyperthermia application of zinc doped nickel ferrite nanoparticles10.1016/j.jpcs.2017.08.018 ↗
60. Optimization of surface coating on Fe3O4 nanoparticles for high performance magnetic hyperthermia agents10.1039/c2jm30472d ↗
61. Enhancement of AC-losses of magnetic nanoparticles for heating applications10.1016/j.jmmm.2004.03.034 ↗
62. Optimum nanoscale design in ferrite based nanoparticles for magnetic particle hyperthermia10.1039/C6RA17892H ↗
63. A simple chemical route toward monodisperse iron carbide nanoparticles displaying tunable magnetic and unprecedented hyperthermia properties10.1021/nl302160d ↗
64. Applications of exchange coupled bi-magnetic hard/soft and soft/hard magnetic core/shell nanoparticles10.1016/j.physrep.2014.09.007 ↗
65. Learning from nature to improve the heat generation of iron-oxide nanoparticles for magnetic hyperthermia applications10.1038/srep01652 ↗
66. Effect of spatial confinement on magnetic hyperthermia via dipolar interactions in Fe3O4 nanoparticles for biomedical applications10.1016/j.msec.2014.04.064 ↗
67. Aggregation effects on the magnetic properties of iron oxide colloids10.1088/1361-6528/aafbff ↗
68. Magnetic heating of silica-coated manganese ferrite nanoparticles10.1016/j.jmmm.2016.02.078 ↗
69. Functionalized hydrophilic superparamagnetic iron oxide nanoparticles for magnetic fluid hyperthermia application in liver cancer treatment10.1021/acsomega.8b00207 ↗
70. Induction heating analysis of surface-functionalized nanoscale CoFe2O4 for magnetic fluid hyperthermia toward noninvasive cancer treatment10.1021/acsomega.0c03332 ↗
71. Role of dipolar interaction in magnetic hyperthermia10.1103/PhysRevB.89.014403 ↗
72. Magnetic hyperthermia in phosphate coated iron oxide nanofluids10.1016/j.jmmm.2016.01.044 ↗
73. Colloidal stability of polyethylene glycol functionalized Co0.5Zn0.5Fe2O4 nanoparticles: effect of pH, sample and salt concentration for hyperthermia application10.1039/c3ra47319h ↗
74. Induction heating and in vitro cytotoxicity studies of MnZnFe2O4 nanoparticles for self-controlled magnetic particle hyperthermia10.1016/j.jallcom.2018.02.174 ↗
75. Hydrophobic to hydrophilic surface transformation of nano-scale zinc ferrite via oleic acid coating: magnetic hyperthermia study towards biomedical applications10.1016/j.ceramint.2019.11.265 ↗
76. Hyperthermic evaluation of oleic acid coated nano-spinel magnesium ferrite: enhancement via hydrophobic-to-hydrophilic surface transformation10.1016/j.jallcom.2020.155422 ↗
77. Heating magnetic fluid with alternating magnetic field10.1016/S0304-8853(02)00706-0 ↗
78. Effect of bismuth doping on the structural and magnetic properties of zinc-ferrite nanoparticles prepared by a microwave combustion method10.1016/j.jmmm.2016.06.080 ↗
79. Structure–redox reactivity relationships in Co1−xZnxFe2O4: the role of stoichiometry10.1039/C8NJ05329D ↗
80. Yafet–Kittel-type magnetic order in Zn-substituted cobalt ferrite nanoparticles with uniaxial anisotropy10.1007/s11051-012-1359-6 ↗
81. AC conductivity, density related and magnetic properties of Ni1−xZnxFe2O4 ferrites with the variation of zinc concentration10.1016/j.matlet.2007.11.019 ↗
82. Substituted cobalt nano-ferrites, CoMxFe2−xO4 (M= Cr3+, Ni2+, Cu2+, Zn2+; 0.2≤ x≤ 1.0) as heterogeneous catalysts for modified Fenton׳s reaction10.1016/j.ceramint.2014.04.019 ↗
83. Tuning of the magnetostrictive properties of cobalt ferrite by forced distribution of substituted divalent metal ions at different crystallographic sites10.1063/1.4977758 ↗
84. Effect of size and site preference of trivalent non-magnetic metal ions (Al3+, Ga3+, In3+) substituted for Fe3+ on the magnetostrictive properties of sintered CoFe2O410.1088/1361-6463/aa8af6 ↗
85. Probing influence of rare earth ions (Er3+, Dy3+ and Gd3+) on structural, magnetic and optical properties of magnetite nanoparticles10.1016/j.jmmm.2018.02.029 ↗
86. Magnetic and structural properties of RE doped Co-ferrite (RE=Nd, Eu, and Gd) nano-particles synthesized by co-precipitation10.1016/j.jmmm.2013.05.030 ↗
87. Effect of Gd3+ doping on magnetic, electric and dielectric properties of MgGdxFe2−xO4 ferrites processed by solid state reaction technique10.1016/j.jallcom.2011.07.055 ↗
88. The effect of Gd3+ and Cd2+ substitution on magnetization of copper ferrite10.1016/S0304-8853(01)00974-X ↗
89. Synthesis, characterization and in vitro cytotoxicity of self-regulating magnetic implant material for hyperthermia application10.1016/j.msec.2009.07.021 ↗
90. Fabrication and magnetic investigation of Y or Gd containing CoFe2O4 nanocrystalline films10.1063/1.368834 ↗
91. Investigations of superparamagnetism in magnesium ferrite nano-sphere synthesized by ultrasonic spray pyrolysis technique for hyperthermia application10.1016/j.jmmm.2015.05.029 ↗
92. A simple model for the size and shape dependent Curie temperature of freestanding Ni and Fe nanoparticles based on the average coordination number and atomic cohesive energy10.1016/j.chemphys.2011.03.010 ↗
93. Nanostructural, magnetic and Mössbauer studies of nanosized Co1−xZnxFe2O4 synthesized by co-precipitation10.1016/j.jmmm.2012.03.008 ↗
94. A systematic study of cobalt-zinc ferrite nanoparticles for self-regulated magnetic hyperthermia10.1016/j.jallcom.2019.04.242 ↗
95. Effect of zinc substitution on Co–Zn and Mn–Zn ferrite nanoparticles prepared by co-precipitation10.1016/j.jmmm.2004.09.138 ↗
96. Magnetocaloric properties of zinc-nickel ferrites around room temperature10.1007/s10948-016-3961-9 ↗
97. MnZnFe nanoparticles for self-controlled magnetic hyperthermia10.1016/j.jmmm.2012.03.043 ↗
98. Magnetic properties of Cu1-xZnxFe2O4 ferrites with the variation of zinc concen-tration10.4236/jmp.2012.35055 ↗
99. Thermoelectric power properties of Zn substituted Cu–Ga spinel ferrites10.1016/j.matlet.2009.01.071 ↗
100. Magnetic and magnetocaloric properties of Cu1−xZnxFe2O4 (x=0.6, 0.7, 0.8) ferrites10.1016/j.jmmm.2014.04.070 ↗