In vitro bioactivity evaluation of magnesium-substituted fluorapatite nanopowders
Source abstract
Abstract
Abstract Properties of apatites, such as bioactivity, biocompatibility, solubility, and adsorption properties can be tailored over a wide range by modifying the composition via ionic substitutions. The aim of this work was preparation, characterization and in vitro bioactivity evaluation of Mg-doped fluorapatite (Mg–FA) nanopowders. Mg–FA nanopowders with different Mg contents were prepared via sol–gel method. In vitro bioactivity evaluation of powders was performed by soaking the powders in simulated body fluid (SBF). Results indicated that Mg ions entered into the fluorapatite lattice and occupied Ca 2+ sites, and the obtained powders had crystallite size about 30–100 nm. With increasing the Mg-substitution, the solubility of powders and the adsorption of Ca 2+ ions onto the powders surfaces increased simultaneously. It was concluded that Mg-substitution improves the bioactivity of FA.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Bone Tissue Engineering Materials · Dental Implant Techniques and Outcomes · Orthopaedic implants and arthroplasty
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (29)
Show source-provided references
1. Aoki · 1994
2. Bioceramics10.1111/j.1151-2916.1998.tb02540.x ↗
3. Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function10.1016/S0142-9612(99)00181-7 ↗
4. Synthesis of hydroxyapatite/fluoroapatite solid solution by a sol–gel method10.1016/S0167-577X(01)00261-0 ↗
5. Calcination and sintering of fluorapatite under argon atmosphere10.1016/S0925-8388(01)01200-2 ↗
6. Influence of fluorine in the synthesis of apatites. Synthesis of solid solutions of hydroxy-fluorapatite10.1016/S0142-9612(03)00259-X ↗
7. Thermal behaviour of magnesium-containing fluorapatite10.1016/S0254-0584(02)00553-9 ↗
8. Osteoblast response to hydroxyapatite doped with divalent and trivalent cations10.1016/j.biomaterials.2003.09.001 ↗
9. Mechanochemical–hydrothermal synthesis of calcium phosphate powders with coupled magnesium and carbonate substitution10.1016/j.jssc.2003.09.012 ↗
10. LeGeros · 1991
11. Improvement of bioactivity with magnesium and fluorine ions incorporated hydroxyapatite coatings via sol–gel deposition on Ti6Al4V alloys10.1016/j.tsf.2009.03.071 ↗
12. Bioactivity of Mg-ion-implanted zirconia and titanium10.1016/j.apsusc.2006.07.038 ↗
13. Magnesium directly stimulates osteoblast proliferation
14. In vitro bioactivity and gene expression by cells cultured on titanium dioxide doped phosphate-based glasses10.1016/j.biomaterials.2007.03.018 ↗
15. Preparation and in vitro bioactivity of CaSiO3 powders10.1016/j.ceramint.2006.12.013 ↗
16. Dissolution and mineralization behaviors of HA coatings10.1016/S0142-9612(03)00371-5 ↗
17. X-ray line broadening from filed aluminium and wolfram10.1016/0001-6160(53)90006-6 ↗
18. How useful is SBF in predicting in vivo bone bioactivity10.1016/j.biomaterials.2006.01.017 ↗
19. Preparation and characterization of magnesium doped hydroxyapatite–gelatin nanocomposite10.1039/b418015c ↗
20. Computational study of cation substitutions in apatites10.1016/j.jssc.2006.02.012 ↗
21. Unstable behavior of magnesium-containing hydroxyapatites10.1159/000260952 ↗
22. Synthesis of Si, Mg substituted hydroxyapatites and their sintering behaviors10.1016/S0142-9612(02)00523-9 ↗
23. Preparation of magnesium-substituted hydroxyapatite powders by the mechanochemical–hydrothermal method10.1016/j.biomaterials.2003.12.008 ↗
24. Measurements of the solubilities and dissolution rates of several hydroxyapatites10.1016/S0142-9612(01)00180-6 ↗
25. Synthesis, characterization and in vitro bioactivity of sol–gel-derived SiO2–CaO–P2O5–MgO bioglass10.1016/j.msec.2008.07.004 ↗
26. A simple route to hydroxyapatite nanofibers10.1016/S0167-577X(02)00539-6 ↗
27. Adsorption of lead ions on ground tyre rubber grafted with maleic anhydride via surface-initiated ATRP polymerization
28. Gradient density grafted polymers on ground tire rubber particles by atom transfer radical polymerization10.1002/macp.200600376 ↗
29. Nucleation of biomimetic Ca–P coatings on Ti6Al4V from a SBF×5 solution: influence of magnesium10.1016/S0142-9612(01)00354-4 ↗