Zinc oxide surface functionalization and related effects on corrosion resistance of titanium implants
Source abstract
Abstract
Abstract Important clinical concerns in orthopedics and dental implantology are associated with a significant release of titanium (Ti) metal ions and debris due to the low corrosion resistance of this material. Chemical modifications on Ti surfaces have been performed in order to minimize effects of corrosion. In this contribution, zinc oxide (ZnO) thin films were deposited onto Ti surfaces and functionalized with four different organic bifunctional molecules in order to increase the corrosion resistance. SEM and XPS indicated the formation of nanostructured ZnO thin film with hydroxyl groups available for covalent functionalization. The adhesion mechanism analyzed by XPS suggest that the attachment on ZnO occurs by carboxylic acid, silane, thiol and hydroxyl groups for 4-aminophenylpropionic acid (APPA), 3-aminopropyltrimetoxysilane (APTMS), 3-mercaptopropionic acid (MPA), and polyethylene glycol (PEG) molecules. Electrochemical analysis for the functionalized ZnO specimens with APPA showed noble open circuit potentials (−0.2 V) and significant decrease in the corrosion current density (5.3 × 10−7 A/cm2) when compared to the values obtained for pristine Ti (−0.56 V and 2.3 × 10−6 A/cm2), indicating a promising material for applications in biomedical fields.
Source: openaire · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Corrosion Behavior and Inhibition · Bone Tissue Engineering Materials · Titanium Alloys Microstructure and Properties
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (63)
Show source-provided references
1. Antimicrobial property, cytocompatibility and corrosion resistance of Zn-doped ZrO2/TiO2 coatings on Ti6Al4V implants10.1016/j.msec.2017.02.036 ↗
2. Antibacterial activity and increased bone marrow stem cell functions of Zn-incorporated TiO2 coatings on titanium10.1016/j.actbio.2011.09.031 ↗
3. A strategy for ZnO nanorod mediated multi-mode cancer treatment10.1016/j.biomaterials.2010.11.027 ↗
4. Cancer-targeted optical imaging with fluorescent zinc oxide nanowires10.1021/nl201782m ↗
5. Wear and corrosion behaviour of Ti–13Nb–13Zr and Ti–6Al–4V alloys in simulated physiological solution10.1016/j.corsci.2010.11.014 ↗
6. Release of metal ions from dental implant materials in vivo: determination of Al, Co, Cr, Mo, Ni, V, and Ti in organ tissue10.1002/jbm.820251204 ↗
7. Corrosion behavior of Zn-incorporated antibacterial TiO2 porous coating on titanium10.1016/j.ceramint.2016.07.220 ↗
8. Absence of aluminium in neuritic plaque cores in Alzheimer's disease10.1038/360065a0 ↗
9. Metal ion release from metal implants10.1016/j.msec.2004.08.018 ↗
10. Effect of Ti, Al, and V ions on the relative growth rate of fibroblasts (L929) and osteoblasts (MC3T3-E1) cells
11. In-vitro corrosion inhibition mechanism of fluorine-doped hydroxyapatite and brushite coated Mg–Ca alloys for biomedical applications10.1016/j.ceramint.2013.12.147 ↗
12. Preparation and characterization of PLA coating and PLA/MAO composite coatings on AZ31 magnesium alloy for improvement of corrosion resistance10.1016/j.surfcoat.2014.11.069 ↗
13. Sol–gel derived mesoporous 58S bioactive glass coatings on AZ31 magnesium alloy and in vitro degradation behavior10.1016/j.surfcoat.2013.12.026 ↗
14. The effect of interlayer on corrosion resistance of ceramic coating/Mg alloy substrate in simulated physiological environment10.1016/j.surfcoat.2012.05.088 ↗
15. Microstructural characterization, biocorrosion evaluation and mechanical properties of nanostructured ZnO and Si/ZnO coated Mg/HA/TiO2/MgO nanocomposites10.1016/j.surfcoat.2015.07.006 ↗
16. The improved performance of Mg-rich epoxy primer on AZ91D magnesium alloy by addition of ZnO10.1016/j.corsci.2014.06.020 ↗
17. Distinct spatial profiles and antibacterial effects of 20-nm Ag nanoparticles dripped on ZnO nanorods grown on a polished Ti substrate10.1016/j.apsusc.2014.05.077 ↗
18. Antibacterial titanium surfaces for medical implants10.1016/j.msec.2015.12.062 ↗
19. Structural transition of ZnO thin films produced by RF magnetron sputtering at low temperatures10.1007/s10854-013-1237-8 ↗
20. Surface modification of ZnO using triethoxysilane-based molecules10.1021/la802621n ↗
21. Surface functionalization of zinc oxide by carboxyalkylphosphonic acid self-assembled monolayers10.1021/la9042827 ↗
22. Effects of Ti surface treatments with silane and arginylglycylaspartic acid peptide on bone cell progenitors10.1007/s10266-014-0169-y ↗
23. Control of hydroxyapatite coating by self-assembled monolayers on titanium and improvement of osteoblast adhesion10.1002/jbm.b.33539 ↗
24. Biofunctional polyethylene glycol coatings on titanium: an in vitro-based comparison of functionalization methods10.1016/j.colsurfb.2017.01.042 ↗
25. J, A facile approach to surface modification on versatile substrates for biological applications
26. Antimicrobial peptide melimine coating for titanium and its in vivo antibacterial activity in rodent subcutaneous infection models10.1016/j.biomaterials.2016.01.063 ↗
27. Photofunctionalization of titanium: an alternative explanation of its chemical-physical mechanism10.1371/journal.pone.0157481 ↗
28. An overview of protein adsorption on metal oxide coatings for biomedical implants10.1016/j.surfcoat.2013.04.028 ↗
29. Synthesis and x-ray diffraction characterization of nanocrystalline ZnO obtained by Pechini method10.1134/S0020168506120119 ↗
30. Microscopic study of surface microtopographic characteristics of dental implants10.2174/1874210601610010139 ↗
31. Surface roughness of dental implants and treatment time using six different implantoplasty procedures10.1111/clr.12682 ↗
32. Surface roughness of implants: a review
33. Synthesis, characterization and antibacterial efficiency of ZnO nanoparticles using rice as soft bio-template10.1016/j.ijleo.2016.01.124 ↗
34. Covalent surface modification of oxide surfaces10.1002/anie.201306709 ↗
35. Biofunctionalization of titanium for dental implant10.1016/j.jdsr.2009.11.001 ↗
36. J.F. Moulder, Handbook of X-ray Photoelectron Spectroscopy: A Reference Book of Standard Spectra for Identification and Interpretation of XPS Data, Physical Electronics Division, Perkin-Elmer Corporation, 1992.
37. Enhanced electrochemical performance of Lithium-ion batteries by conformal coating of polymer electrolyte10.1186/1556-276X-9-544 ↗
38. Thermal and UV hydrosilylation of alcohol-based Bifunctional Alkynes on Si (111) surfaces: how surface radicals influence surface bond formation10.1038/srep11299 ↗
39. Adsorption of L-cysteine on rutile TiO2(110)10.1016/j.susc.2010.10.017 ↗
40. The adsorption and reactions of the amino acid proline on rutile TiO2(110) surfaces10.1016/j.susc.2008.04.010 ↗
41. Optimized monolayer grafting of 3-aminopropyltriethoxysilane onto amorphous, anatase and rutile TiO210.1016/j.susc.2009.11.027 ↗
42. Synthesis of flower-like Ag-ZnO nanostructure and its application in the photodegradation of methyl orange
43. Adsorption and reaction of glycine on the rutile TiO2(011) single crystal surface10.1016/j.susc.2010.10.020 ↗
44. Mittal · 2009
45. Wingrave · 2001
46. Chemical functionalization of surfaces for building three-dimensional engineered biosensors10.1016/j.apsusc.2012.12.099 ↗
47. Examination of zinc oxide films prepared by magnetron sputtering10.1016/j.protcy.2016.03.034 ↗
48. Titanium surface characteristics, including topography and wettability, alter macrophage activation10.1016/j.actbio.2015.12.003 ↗
49. Harris · 1992
50. Characterization of ultrathin poly(ethylene glycol) monolayers on silicon substrates10.1021/la000609d ↗
51. Effect of ZnO morphology on affecting bactericidal property of ultra high molecular weight polyethylene biocomposite10.1016/j.msec.2016.02.032 ↗
52. Implantation of hydrophilic and hydrophobic titanium discs in rat tibia: cellular reactions on the surfaces during the first 3 weeks in bone10.1016/j.biomaterials.2003.12.006 ↗
53. Photoinduced hydrophilic conversion of hydrated ZnO surfaces10.1016/j.jcis.2015.08.015 ↗
54. Exploration of wettability and optical aspects of ZnO nano thin films synthesized by radio frequency magnetron sputtering10.5772/62804 ↗
55. Resistance of solid surfaces to wetting by water10.1021/ie50320a024 ↗
56. Surface modification of surface sol–gel derived titanium oxide films by self-assembled monolayers (SAMs) and non-specific protein adsorption studies10.1016/j.colsurfb.2004.12.009 ↗
57. Comparison of degradation mechanisms in organic photovoltaic devices upon exposure to a temperate and a subequatorial climate10.1016/j.cplett.2015.09.023 ↗
58. Applications of dynamic electrochemical impedance spectroscopy (DEIS) to evaluate protective coatings formed on AZ31 magnesium alloy10.1039/C4RA16967K ↗
59. Kelly · 2002
60. Defect area determination of organic coated steels in seawater using the breakpoint frequency method10.1149/1.2085574 ↗
61. Electrochemical behavior of (Ti1−xNbx)5Si3 nanocrystalline films in simulated physiological media10.1016/j.actbio.2013.09.021 ↗
62. Ducheyne · 2011
63. Role of plastic deformation and microstructure in the micro-electrochemical behaviour of Ti–6Al–4V in sodium chloride solution10.1016/j.electacta.2012.12.029 ↗