journal article·2021-06-01Open access

Innovation in a Time of Crisis: A Systematic Review of Three-Dimensional Printing in the COVID-19 Pandemic

Nader Ibrahim, Thomas Jovic, Zita M. Jessop, Iain S. Whitaker

Abstract

The coronavirus (COVID-19) global pandemic resulted in the breakdown of traditional supply chains responsible for providing essential equipment to hospitals and personal protective equipment (PPE) for health and social care workers. The three-dimensional (3D) printing community has responded to emerging need by recognizing shortages across health care systems and providing innovative solutions in real time, circumventing short-term global supply issues. A systematic review was undertaken to investigate the role of 3D printing in the COVID-19 pandemic in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using the MEDLINE, EMBASE, and World Health Organization (WHO) COVID-19 databases. Newspaper and internet article sources were identified using the NEXIS media database. All studies and articles on the application of 3D printed solutions during the peak of the COVID-19 pandemic were included. The literature search identified 26 related articles, and 13 studies met inclusion criteria and were suitable for full-text review. One thousand two hundred and one unique digital media articles were identified; after removal of duplicates and screening of headlines for the inclusion and exclusion criteria, 460 articles were suitable for full-text review. The cross-collaboration between the 3D printing community and health care systems has aided in the provision of innovative solutions to combat the COVID-19 crisis. The applications for 3D printing ranged from oxygenation equipment to noninvasive and invasive ventilatory parts and innovative solutions for infection control and quarantine hubs. This review has identified that 3D printing technology has made the biggest contribution to the production of PPE in particular face shields, mirroring the areas of greatest shortage and need. Additive manufacturing has played a pivotal role in aligning disciplines in engineering, science, and medicine for the greater good. We have witnessed the rapid reconfiguration of traditional supply chains to circumvent global shortages, while making advancements in effort to limit the impact of this and future pandemics.
Source: crossref · Quality: baseline

Research context

OpenAlex topics: Infection Control and Ventilation · COVID-19 and healthcare impacts · COVID-19 and Mental Health

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Reconstructive Surgery and Regenerative Medicine Research Group (ReconRegen), Institute of Life Sciences, Swansea University Medical School, Swansea, United Kingdom.

The Welsh Centre for Burns & Plastic Surgery, Morriston Hospital, Swansea, United Kingdom.

References (55)

Show source-provided references
1. 10.1016/S0140-6736(20)30967-310.1016/S0140-6736(20)30967-3 ↗
2. World Health Organization. Shortage of personal protective equipment endangering health workers worldwide. https://www.who.int/news-room/detail/03-03-2020-shortage-of-personal-protective-equipment-endangering-health-workers-worldwide (accessed May16 2020).
3. 10.1016/S0140-6736(20)30566-310.1016/S0140-6736(20)30566-3 ↗
4. 10.1002/bjs.1175010.1002/bjs.11750 ↗
5. 10.3396/ijic.v9i1.003.1310.3396/ijic.v9i1.003.13 ↗
6. The Lancet. COVID-19: Protecting health-care workers. Lancet, 2020; 395:922.
7. Campbell D. One in three UK surgeons lacks enough protective kit survey finds. The Guardian.
8. Smyth C Swinford S Lay K . Coronavirus facemasks for public ‘risk NHS shortage . ’ April 21 2020. https://www.thetimes.co.uk/article/facemasks-for-public-risk-nhs-shortage-q5bkzvzql (accessed April22 2020).
9. Ferguson NM Laydon D Nedjati-Gilani G et al. Impact of non-pharmaceutical interventions (NPIs) to reduce COVID-19 mortality and healthcare demand. London: Imperial College London 2020; pp. 3–20.
10. 10.1056/NEJMp200614110.1056/NEJMp2006141 ↗
11. 3D Printing Media Network. Open source projects. https://www.3dprintingmedia.network/forums/forum/am-in-the-time-of-covid-19-forum/open-source-projects (accessed May16 2020).
12. U.S. Department of Health and Human Services—National Institutes of Health. US National Institutes of Health 3D Print Exchange. https://3dprint.nih.gov/collections/covid-19-response (accessed May16 2020).
13. COVID-19 Call to Action. 3D Systems. https://uk.3dsystems.com/covid-19-response (accessed May16 2020).
14. Popay J Roberts H Sowden A et al. Developing guidance on the conduct of narrative synthesis in systematic reviews. A Product from the ESRC Methods Program. Lancaster: Institute for Health Research Lancaster University 2005.
15. US Food and Drug Administration (FDA). Coronavirus (COVID-19) supply chain update. https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-supply-chain-update (accessed April12 2020).
16. UK Government. COVID-19: Infection prevention and control (IPC). https://www.gov.uk/government/publications/wuhan-novel-coronavirus-infection-prevention-and-control (accessed April12 2020).
17. Decathalon. Subea surface snorkelling mask easybreath 500. https://www.decathlon.co.uk/mask-easybreath-500-turquoise-id_8491269.html (accessed April12 2020).
18. Prakash Lab. The pneumask project. https://www.pneumask.org/ (accessed April12 2020).
19. 3M. 3M™ particulate filter 2091/07000(AAD) P100 100 https://www.3m.com/3M/en_LB/p/d/v000093499/ (accessed April12 2020).
20. US Food and Drug Administration (FDA). Emergency use authorization. https://www.fda.gov/emergency-preparedness-and-response/mcm-legal-regulatory-and-policy-framework/emergency-use-authorization (accessed April12 2020).
21. VHA. Stopgap surgical face mask (SFM). https://3dprint.nih.gov/discover/3dpx-013429 (accessed April12 2020).
22. Roundtable. NRC (US) CS. Commodity polymers from renewable resources: Polylactic acid. https://www.ncbi.nlm.nih.gov/books/NBK44131 (accessed April23 2020).
23. EOS. Polyamide 12 in 3D printing. https://www.eos.info/de/additive-fertigung/3d-druck-kunststoffe/polymer-material-werkstoffe/polyamid-pa-12-alumide (accessed April12 2020).
24. 10.3390/ijms1601209910.3390/ijms16012099 ↗
25. 10.1016/j.ijantimicag.2018.02.00710.1016/j.ijantimicag.2018.02.007 ↗
26. Feldman A . Meet the Italian engineers 3D-printing respirator parts for free to help keep coronavirus patients aliveitle. March 19 2020. https://www.forbes.com/sites/amyfeldman/2020/03/19/talking-with-the-italian-engineers-who-3d-printed-respirator-parts-for-hospitals-with-coronavirus-patients-for-free/#588db89278f1 (accessed April29 2020).
27. Grabcad Community. Venturi valve. https://grabcad.com/library/respirator-free-reanimation-venturi-s-valve-rev-4-1 (accessed April12 2020).
28. Kent C. Covid-19: Start-up that saved lives with 3D-printed valve may face legal action. March 18 2020. https://www.medicaldevice-network.com/news/3d-printed-valves-covid-19-italy (accessed March29 2020).
29. 10.1197/j.aem.2006.05.00910.1197/j.aem.2006.05.009 ↗
30. Evaluation of known projects. https://github.com/PubInv/covid19-vent-list (accessed May16 2020).
31. Medtronic. Medtronic releases all CAD files and PC B schematics for PB560 ventilator manufacturing. https://www.3dprintingmedia.network/medtronic-releases-pb560-ventilator-files (accessed April12 2020).
32. Club Sandwich Studio. M.U.R minimal universal respirator. https://mur-project.org/en-home (accessed April12 2020).
33. Materialise. Hands-free 3D-printed door openers to help against the spread of coronavirus. https://www.materialise.com/en/hands-free-door-opener (accessed April23 2020).
34. Swansea University. South Wales industry consortium established to support the NHS COVID 19 response. https://www.swansea.ac.uk/press-office/news-events/news/2020/03/south-wales-industry-consortium-established-to-support-the-nhs-covid-19-response.php (accessed June7 2020).
35. CECIMO. Additive manufacturing. https://www.cecimo.eu/machine-tools/additive (accessed June7 2020).
36. Copper3D. #HackThePandemic. https://copper3d.com/hackthepandemic (accessed June8 2020).
37. Clark L. Leading the way. https://www.harvardbusiness.org/innovation-in-a-time-of-crisis (accessed June7 2020).
38. US Food and Drug Administration (FDA). Medical devices and the COVID-19 pandemic. https://www.fda.gov/medical-devices/emergency-situations-medical-devices/medical-devices-and-covid-19-pandemic (accessed June7 2020).
39. Medical Countermeasures.gov. 2019 Novel coronavirus. https://www.medicalcountermeasures.gov/Request-BARDA-TechWatch-Meeting (accessed June7 2020).
40. 10.3390/ijms2005121010.3390/ijms20051210 ↗
41. JustGiving. 3D printed face shields. https://www.justgiving.com/crowdfunding/3d-printed-face-visor-covid19 (accessed May16 2020).
42. Crowdfunder. 3D PPE prints for Covid-19—Highlands. Available from: https://www.crowdfunder.co.uk/covid-19-highlands (accessed May16 2020).
43. 10.3390/ma1308199710.3390/ma13081997 ↗
44. 10.3390/prosthesis202000510.3390/prosthesis2020005 ↗
45. 10.1016/j.diii.2020.04.00410.1016/j.diii.2020.04.004 ↗
46. Larrañeta E, , Dominguez-Robles J, , Lamprou DA. Additive manufacturing can assist in the fight against COVID-19 and Other Pandemics and Impact on the Global Supply Chain. 3D Print Addit Manuf, 2020; 7:1–3.
47. 10.1016/j.amjmed.2020.04.00210.1016/j.amjmed.2020.04.002 ↗
48. 10.1186/s41205-020-00064-710.1186/s41205-020-00064-7 ↗
49. 10.1016/j.arth.2020.04.03510.1016/j.arth.2020.04.035 ↗
50. 10.1053/j.jvca.2020.04.00410.1053/j.jvca.2020.04.004 ↗
51. 10.1080/17434440.2020.175677110.1080/17434440.2020.1756771 ↗
52. 10.1093/labmed/lmaa03110.1093/labmed/lmaa031 ↗
53. 10.1016/j.dsx.2020.04.04810.1016/j.dsx.2020.04.048 ↗
54. 10.1016/j.ijom.2020.03.01510.1016/j.ijom.2020.03.015 ↗
55. 10.1038/d41586-020-01246-310.1038/d41586-020-01246-3 ↗