Polymeric nanogels and hybrid platforms for redox modulation from ROS biology to therapeutic design
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OpenAlex topics: Nanoplatforms for cancer theranostics · Hydrogels: synthesis, properties, applications · Nanoparticle-Based Drug Delivery
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References (100+)
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1. Reactive oxygen species (ROS) and antioxidant systems in enhancing plant resilience against abiotic stress10.1155/ioa/8834883 ↗
2. Emodin-derived red-emissive carbon dots: Light-driven ROS generation and antioxidant activities in non-illuminative regimes10.1016/j.biomaterials.2025.123496 ↗
3. Endogenous and exogeneous stimuli-triggered reactive oxygen species evoke long-lived carbon monoxide to fight against lung cancer10.1186/s12951-024-02688-x ↗
4. The dual role of PGAM5 in inflammation10.1038/s12276-025-01391-7 ↗
5. Reactive oxygen species (ROS): sources, generation, disease pathophysiology, and antioxidants10.1007/s44371-025-00275-z ↗
6. ROS Are Good10.1016/j.tplants.2016.08.002 ↗
7. Beyond antioxidants: How redox pathways shape cellular signaling and disease outcomes10.3390/antiox14091142 ↗
8. Reactive oxygen species-post translational modifications-central carbon metabolism regulatory loop: coordination of redox homeostasis and carbon flux allocation in plants under abiotic stress10.3389/fpls.2025.1637328 ↗
9. Oxidative Stress: Signaling Pathways, Biological Functions, and Disease10.1002/mco2.70268 ↗
10. Mitochondria reactive oxygen species signaling in immune responses10.1016/j.immuni.2025.07.012 ↗
11. Understanding chronic inflammation: couplings between cytokines, ROS, NO, Cai 2+, HIF-1α, Nrf2 and autophagy10.3389/fimmu.2025.1558263 ↗
12. Ferumoxytol promotes haematopoietic stem cell post-injury regeneration as a reactive oxygen species scavenger10.1038/s41565-025-01907-2 ↗
13. Nanozymes as next-generation ROS scavengers: design strategies, catalytic mechanisms, and therapeutic frontiers10.1039/D5TB00849B ↗
14. Antioxidants and reactive oxygen species: shaping human health and disease outcomes10.3390/ijms26157520 ↗
15. The role of redox-active iron, copper, manganese, and redox-inactive zinc in toxicity, oxidative stress, and human diseases
16. Anti-Oxidative Tannic Acid-Based Nanogels Formed via Dynamic Benzoxaborolate Cross-Linking at Physiological pH10.1016/j.molliq.2024.124239 ↗
17. Reactive Oxygen Species (ROS) and Their Profound Influence on Regulating Diverse Aspects of Cancer: A Concise Review10.1002/ddr.70107 ↗
18. Switching on a transient endogenous ROS production in mammalian cells and tissues10.1016/j.ymeth.2016.08.013 ↗
19. Salt stress-accelerated proteasomal degradation of LBD11 suppresses ROS-mediated meristem development and root growth in Arabidopsis10.1016/j.xplc.2025.101241 ↗
20. Pathological and Inflammatory Consequences of Aging10.3390/biom15030404 ↗
21. Radiation-Resistant Bacteria Deinococcus radiodurans-Derived Extracellular Vesicles as Potential Radioprotectors10.1002/adhm.202403192 ↗
22. Surviving the storm: exploring the role of natural transformation in nutrition and DNA repair of stressed Deinococcus radiodurans10.1128/aem.01371-24 ↗
23. Oxidative stress in cadmium toxicity in animals and its amelioration
24. Protective effects and mechanism of chemical-and plant-based selenocystine against cadmium-induced liver damage10.1016/j.jhazmat.2024.133812 ↗
25. The reaction of sulfenic acids with OH and HO2 radicals in different environments10.1039/D4CP04106B ↗
26. Mesoporous polydopamine@CeO2 nanoparticles for photoacoustic-guided photothermal therapy in suppressing arthritis
27. Redox imbalance in inflammation: the interplay of oxidative and reductive stress10.3390/antiox14060656 ↗
28. Cobalt carbonate nanorods enhance chemotherapy via neutralization of acidic tumor microenvironment and generation of carbonate radical anions for necrosis10.1016/j.colsurfb.2025.114563 ↗
29. Acid-neutralizing zinc-magnesium double hydroxide nanosheets reverse osteoporotic microenvironment by targeting the osteoclast calcium oscillation10.1016/j.celbio.2025.100015 ↗
30. A liquid PEG depot capable of triggering intratumoral O2/H2O2 generation and neutralization/calcification for realizing light irradiation-free photodynamic therapy and immunotherapy
31. Gnetupendin A attenuates ischemic stroke injury by modulating oxidative stress through AMPK/SIRT1 pathway10.1016/j.bcp.2025.117294 ↗
32. Oxidative Stress and Inflammation: Drivers of Tumorigenesis and Therapeutic Opportunities10.3390/antiox14060735 ↗
33. Harnessing Redox: Biocomposites Modulate Macrophage-Stem Cell Dynamics in Osteo-Inflammation
34. ROS-responsive nanoplatforms for targeted tumor immunomodulation: a paradigm shift in precision cancer immunotherapy10.3390/pharmaceutics17070886 ↗
35. Thermo-Responsive Polymer-Based Nanoparticles: From Chemical Design to Advanced Applications10.1002/marc.202401127 ↗
36. A reactive oxygen species-responsive hydrogel loaded with Apelin-13 promotes the repair of spinal cord injury by regulating macrophage M1/M2 polarization and neuroinflammation
37. Multifunctional carboxymethylcellulose–based nanogel containing Matricaria chamomilla essential oil: A practical approach to combating skin aging in rats10.1016/j.ijbiomac.2025.149183 ↗
38. ROS-scavenging nanoparticles loaded with tectorigenin protect against acetaminophen-induced hepatotoxicity by interrupting the calcium/ROS-mediated pathogenic endoplasmic reticulum–Mitochondrial signaling cascade
39. Amphiphilic pH-responsive core-shell nanoparticles can increase the performances of cellulose-based drug delivery systems10.1016/j.ijbiomac.2024.137659 ↗
40. Reactive oxygen species driven prodrug-based nanoscale carriers for transformative therapies10.1039/D4BM00647J ↗
41. Mesoporous polydopamine nanoplatforms loaded with calcium ascorbate for amplified oxidation and photothermal combination cancer therapy10.1002/bmm2.12041 ↗
42. Recent advances in reactive oxygen species (ROS)-responsive drug delivery systems for photodynamic therapy of cancer10.1016/j.apsb.2024.10.015 ↗
43. Research progress of reactive oxygen species (ROS) scavenging nanoplatforms in the treatment of ocular diseases10.1016/j.jconrel.2025.114078 ↗
44. Reactive oxygen species: drivers of physiological and pathological processes10.2147/JIR.S275595 ↗
45. Oxidative stress and inflammation in the pathogenesis of neurological disorders: Mechanisms and implications10.1016/j.apsb.2024.10.004 ↗
46. Oxidative stress and free radicals in disease pathogenesis: a review10.1007/s44337-025-00303-y ↗
47. ROS induced lipid peroxidation and their role in ferroptosis10.3389/fcell.2023.1226044 ↗
48. Reactive oxygen species (ROS) as pleiotropic physiological signalling agents10.1038/s41580-020-0230-3 ↗
49. Targeting Labile Iron-Mediated Ferroptosis Provides a Potential Therapeutic Strategy for Rhabdomyolysis-Induced Acute Kidney Injury10.1021/acschembio.2c00914 ↗
50. Ferroptosis: past, present and future10.1038/s41419-020-2298-2 ↗
51. Reactive oxygen species-induced lipid peroxidation in apoptosis, autophagy, and ferroptosis
52. Inhibition of tubular epithelial cells ferroptosis alleviates renal interstitial fibrosis by reducing lipid hydroperoxides and TGF-β/Smad signaling10.1186/s12964-025-02068-4 ↗
53. The role of ferroptosis and oxidative stress in cognitive deficits among chronic schizophrenia patients: a multicenter investigation10.1038/s41537-025-00555-8 ↗
54. Unraveling molecular and genetic insights into neurodegenerative diseases: advances in understanding Alzheimer’s, Parkinson’s, and Huntington’s diseases and amyotrophic lateral sclerosis10.3390/ijms241310809 ↗
55. Oxidative Stress in Neurodegenerative Diseases10.3390/antiox11030504 ↗
56. Microenvironment modulating nanogels by Shiitake-derived lentinan and a reactive oxygen species scavenging conjugated polymer for the treatment of Alzheimer’s disease10.1016/j.nantod.2024.102178 ↗
57. Aconitum carmichaelii triggers neurotoxicity and Parkinson-like symptoms through initiation of ROS-mitochondrial apoptosis and the Nox5/DJ-1 signaling pathway10.1002/bmm2.12019 ↗
58. The interplay of iron, oxidative stress, and α-synuclein in Parkinson’s disease progression10.1186/s10020-025-01208-3 ↗
59. Iron imbalance in neurodegeneration10.1038/s41380-023-02399-z ↗
60. Chronic inflammatory disorders and their redox control: from molecular mechanisms to therapeutic opportunities10.1089/ars.2010.3547 ↗
61. PPARγ regulates osteoarthritis chondrocytes apoptosis through caspase-3 dependent mitochondrial pathway
62. Reactive oxygen species, aging and articular cartilage homeostasis10.1016/j.freeradbiomed.2018.08.038 ↗
63. The impact of mitochondrial dysfunction on osteoarthritis cartilage: current insights and emerging mitochondria-targeted therapies10.1038/s41413-025-00460-x ↗
64. Role of reactive oxygen species and mitochondrial damage in rheumatoid arthritis and targeted drugs10.3389/fimmu.2023.1107670 ↗
65. IL33-induced neutrophil extracellular traps (NETs) mediate a positive feedback loop for synovial inflammation and NET amplification in rheumatoid arthritis10.1038/s12276-024-01351-7 ↗
66. Neutrophils with low production of reactive oxygen species are activated during immune priming and promote development of arthritis10.1016/j.redox.2024.103401 ↗
67. Ferrostatin-1 reduces the inflammatory response of rheumatoid arthritis by decreasing the antigen presenting function of fibroblast-like synoviocytes10.1186/s12967-025-06300-0 ↗
68. Nanomaterial-based reactive oxygen species scavengers for osteoarthritis therapy10.1016/j.actbio.2023.03.030 ↗
69. The interplay between oxidative stress and lipid composition in obesity-induced inflammation: Antioxidants as therapeutic agents in metabolic diseases10.3390/ijms26178544 ↗
70. Cellular death, reactive oxygen species (ROS) and diabetic complications10.1038/s41419-017-0135-z ↗
71. Cellular and molecular roles of reactive oxygen species in wound healing10.1038/s42003-024-07219-w ↗
72. The role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases10.1007/s00210-014-0985-1 ↗
73. Reactive oxygen species in colorectal cancer adjuvant therapies
74. Comprehensive review of methodology to detect reactive oxygen species (ROS) in mammalian species and establish its relationship with antioxidants and cancer10.3390/antiox10010128 ↗
75. Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo10.1038/s42255-022-00591-z ↗
76. Measuring ROS and redox markers in plant cells10.1039/D1CB00071C ↗
77. Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cells10.1016/j.tiv.2013.01.016 ↗
78. MitoSOX-based flow cytometry for detecting mitochondrial ROS
79. Comparative study of DPPH, ABTS and FRAP assays for determination of antioxidant activity
80. Studies on antibacterial activity of ZnO nanoparticles by ROS induced lipid peroxidation10.1016/j.colsurfb.2012.01.046 ↗
81. Nutritional countermeasures targeting reactive oxygen species in cancer: from mechanisms to biomarkers and clinical evidence10.1089/ars.2012.4662 ↗
82. Reactive oxygen species (ROS)-based nanomedicine10.1021/acs.chemrev.8b00626 ↗
83. Superoxide signalling and antioxidant processing in the plant nucleus10.1093/jxb/erae090 ↗
84. Hydrogen peroxide transport by aquaporins: insights from molecular modeling and simulations10.1007/s12551-025-01288-9 ↗
85. Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: Oxidative eustress10.1016/j.redox.2016.12.035 ↗
86. From Framework to Radical Pathways: A Critical Review on MOF-Driven Fenton and Fenton-Like Catalysis10.1007/s41742-026-01066-9 ↗
87. Lipid peroxidation and antioxidant protection10.3390/biom13091291 ↗
88. Recent advances in fluorescent probes of peroxynitrite: Structural, strategies and biological applications10.7150/thno.80529 ↗
89. Designing polymers with stimuli-responsive degradation for biomedical applications
90. Biocompatible polymeric nanoparticles degrade and release cargo in response to biologically relevant levels of hydrogen peroxide10.1021/ja303372u ↗
91. Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging10.1007/s00204-023-03562-9 ↗
92. The Interplay of Oxidative Stress and ROS Scavenging: Antioxidants as a Therapeutic Potential in Sepsis
93. Endogenous non-enzymatic antioxidants in the human body10.1016/j.advms.2017.05.005 ↗
94. Free radicals and their impact on health and antioxidant defenses: a review10.1038/s41420-024-02278-8 ↗
95. Synthetic cationic helical polypeptides for the stimulation of antitumour innate immune pathways in antigen-presenting cells10.1038/s41551-024-01194-7 ↗
96. Magnetically Active Bicontinuous Polymer Structures for Multiple Controlled Drug Delivery
97. Flash nanoprecipitation permits versatile assembly and loading of polymeric bicontinuous cubic nanospheres10.1039/C7NR06779H ↗
98. Recent Advances of Organic-Inorganic Hybrid Fluorescent Hyperbranched Polymer: Synthesis, Performance Regulation Strategies and Applications10.1002/cplu.202400302 ↗
99. Adsorption effects of electron scavengers and inorganic ions on catalysts for catalytic oxidation of sulfamethoxazole in radiation treatment10.1016/j.chemosphere.2024.141675 ↗
100. Manganese Porphyrin Treatment Improves Redox Status Caused by Acute Compressive Spinal Cord Trauma10.3390/antiox14050587 ↗