journal article·2025-10Open access

Actin rings as mechanical barriers in endothelial resistance to tumor invasion

Chaohui Jiang, Guangsong Xie, Qianchun Wang, Baohua Ji

Cell Reports Physical Science· Volume 6· Issue 10

Abstract

Publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies including Cell, Neuron, Immunity, Current Biology, AJHG, and the Trends Journals.
Only a short abstract or summary was supplied by the source.
Source: openalex_inverted_index · Quality: short

Research context

OpenAlex topics: Cellular Mechanics and Interactions · Cell Adhesion Molecules Research · Microtubule and mitosis dynamics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (41)

Show source-provided references
1. Actomyosin Ring Formation and Tension Generation in Eukaryotic Cytokinesis10.1016/j.cub.2016.06.071 ↗
2. Actin ring segment switching drives nonadhesive gap closure10.1073/pnas.2010960117 ↗
3. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism10.1016/S0960-9822(01)00587-5 ↗
4. Zebrafish epiboly: mechanics and mechanisms10.1387/ijdb.093028sl ↗
5. Dynamic Analysis of Actin Cable Function during Drosophila Dorsal Closure10.1016/S0960-9822(02)00955-7 ↗
6. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited10.1038/nrc1098 ↗
7. Tumor Metastasis: Molecular Insights and Evolving Paradigms10.1016/j.cell.2011.09.024 ↗
8. Crossing the endothelial barrier during metastasis10.1038/nrc3628 ↗
9. In vitro Studies of Transendothelial Migration for Biological and Drug Discovery10.3389/fmedt.2020.600616 ↗
10. Mechanisms of leukocyte transendothelial migration10.1146/annurev-pathol-011110-130224 ↗
11. Atomic Force Microscopy Reveals a Role for Endothelial Cell ICAM-1 Expression in Bladder Cancer Cell Adherence10.1371/journal.pone.0098034 ↗
12. Endothelial cell adhesion molecules and cancer progression10.2174/092986707779941032 ↗
13. Cell–cell interactions during transendothelial migration of tumor cells10.1002/(SICI)1097-0029(19981101)43:3<265::AID-JEMT9>3.0.CO;2-Z ↗
14. Endothelial Cell-to-Cell Junctions: Molecular Organization and Role in Vascular Homeostasis10.1152/physrev.00035.2003 ↗
15. Mechanical Adaptability of Tumor Cells in Metastasis10.1016/j.devcel.2020.10.011 ↗
16. Effects of extracellular matrix viscoelasticity on cellular behaviour10.1038/s41586-020-2612-2 ↗
17. Cell Adhesion and Matrix Stiffness: Coordinating Cancer Cell Invasion and Metastasis10.3389/fonc.2018.00145 ↗
18. Feeling Things Out: Bidirectional Signaling of the Cell–ECM Interface, Implications in the Mechanobiology of Cell Spreading, Migration, Proliferation, and Differentiation10.1002/adhm.201901445 ↗
19. Physical influences of the extracellular environment on cell migration10.1038/nrm3897 ↗
20. Mechanism of regulation of stem cell differentiation by matrix stiffness10.1186/s13287-015-0083-4 ↗
21. Biophysical regulation of tumor cell invasion: moving beyond matrix stiffness10.1039/c0ib00095g ↗
22. Tensional homeostasis and the malignant phenotype10.1016/j.ccr.2005.08.010 ↗
23. Matrix stiffness enhances VEGFR-2 internalization, signaling, and proliferation in endothelial cells10.1088/2057-1739/aa9263 ↗
24. Biomechanical forces promote embryonic haematopoiesis10.1038/nature08073 ↗
25. Actin Rings of Power10.1016/j.devcel.2016.05.024 ↗
26. Nuclear stiffening inhibits migration of invasive melanoma cells10.1007/s12195-014-0358-3 ↗
27. How do multiple active cellular forces co-regulate wound shape evolution?10.1016/j.jmps.2024.105864 ↗
28. Dissecting Collective Cell Behavior in Polarization and Alignment on Micropatterned Substrates10.1016/j.bpj.2015.06.058 ↗
29. Some basic questions on mechanosensing in cell–substrate interaction10.1016/j.jmps.2014.05.016 ↗
30. Collective cell guidance by cooperative intercellular forces10.1038/nmat3025 ↗
31. A theoretical model of collective cell polarization and alignment10.1016/j.jmps.2019.103860 ↗
32. Endothelium and Subendothelial Matrix Mechanics Modulate Cancer Cell Transendothelial Migration10.1002/advs.202206554 ↗
33. Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival10.1083/jcb.201308029 ↗
34. Cancer cell motility: lessons from migration in confined spaces10.1038/nrc.2016.123 ↗
35. Lamin A/C deficiency causes defective nuclear mechanics and mechanotransduction10.1172/JCI200419670 ↗
36. Reduced Lamin A/C Does Not Facilitate Cancer Cell Transendothelial Migration but Compromises Lung Metastasis10.3390/cancers13102383 ↗
37. Increase in endothelial cell density before artery enlargement in flow-loaded canine carotid artery10.1161/01.ATV.9.6.812 ↗
38. Endothelial cells in peripheral blood of healthy subjects and patients with metastatic carcinomas10.1002/cyto.a.20364 ↗
39. Fabrication of Biofunctionalized Quasi-Three-Dimensional Microstructures of a Nonfouling Comb Polymer Using Soft Lithography10.1002/adfm.200400088 ↗
40. Stresses at the Cell-to-Substrate Interface during Locomotion of Fibroblasts10.1016/S0006-3495(99)77386-8 ↗
41. Landau · 1986