An optimal portfolio of photothermal combined immunotherapy
Source abstract
Abstract
Photothermal therapy (PTT) applies photothermal agents to convert light into heat to eliminate primary tumors and induce subsequent immune responses, but the ineffectiveness in metastatic or recurrent tumors hinders its further use. Based on adaptive immunity, immunotherapy can suppress tumor growth, but the immunosuppressive tumor microenvironment limits the therapeutic effect. Excellent synergistic effects on primary and distant tumors have been found in many studies combining two therapies. In this review, the principles, materials, and latest research on photothermal immunotherapy are described in detail. The advantages and disadvantages of the combination therapy and its development prospects are also discussed rationally, which we hope will provide readers with both basic background knowledge of and cutting-edge research content about the combination therapy.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Immunotherapy and Immune Responses · Cancer Immunotherapy and Biomarkers
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (100+)
Show source-provided references
1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2. Cancer nanomedicine: progress, challenges and opportunities
3. Tumor delivery of macromolecular drugs based on the EPR effect10.1016/j.addr.2010.03.011 ↗
4. Charge-reversal nanomedicines as a smart bullet for deep tumor penetration
5. The Edwin Smith Surgical Papyrus: Published in Facsimile and Hieroglyphic Transliteration with Translation and Commentary in Two Volumes
6. Clinical development and potential of photothermal and photodynamic therapies for cancer10.1038/s41571-020-0410-2 ↗
7. Near-infrared II phototherapy induces deep tissue immunogenic cell death and potentiates cancer immunotherapy10.1021/acsnano.9b06040 ↗
8. Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer
9. Near-infrared photonic energy penetration: can infrared phototherapy effectively reach the human brain?10.2147/NDT.S78182 ↗
10. Thermal and optical properties of living tissue: application to laser-induced hyperthermia10.1002/lsm.1900050607 ↗
11. Nivolumab plus ipilimumab in advanced non–small-cell lung cancer10.1056/NEJMoa1910231 ↗
12. Tumour-intrinsic resistance to immune checkpoint blockade10.1038/s41577-019-0218-4 ↗
13. Immune-related adverse events associated with immune checkpoint blockade10.1056/NEJMra1703481 ↗
14. Mutations associated with acquired resistance to PD-1 blockade in melanoma10.1056/NEJMoa1604958 ↗
15. Cancer immunotherapy comes of age10.1038/nature10673 ↗
16. TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance10.1016/j.molimm.2007.01.022 ↗
17. PD-1/PD-L1 immune checkpoint: potential target for cancer therapy10.1002/jcp.27172 ↗
18. Heat shock proteins, tumor immunogenicity and antigen presentation: an integrated view10.1016/S0167-5699(99)01558-3 ↗
19. Current approaches of photothermal therapy in treating cancer metastasis with nanotherapeutics10.7150/thno.14988 ↗
20. Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death10.1084/jem.20050915 ↗
21. Consensus guidelines for the detection of immunogenic cell death10.4161/21624011.2014.955691 ↗
22. Hyperthermia can alter tumor physiology and improve chemo-and radio-therapy efficacy10.1016/j.addr.2020.07.007 ↗
23. Oncology meets immunology: the cancer-immunity cycle10.1016/j.immuni.2013.07.012 ↗
24. PolyTLR7/8a-conjugated, antigen-trapping gold nanorods elicit anticancer immunity against abscopal tumors by photothermal therapy-induced in situ vaccination10.1016/j.biomaterials.2021.120921 ↗
25. Surgical tumor-derived personalized photothermal vaccine formulation for cancer immunotherapy10.1021/acsnano.8b07371 ↗
26. Laser-photosensitizer assisted immunotherapy: a novel modality for cancer treatment10.1016/S0304-3835(97)04707-1 ↗
27. Chemo-photothermal therapy combination elicits anti-tumor immunity against advanced metastatic cancer10.1038/s41467-018-03473-9 ↗
28. Immunological responses triggered by photothermal therapy with carbon nanotubes in combination with anti-CTLA-4 therapy to inhibit cancer metastasis10.1002/adma.201402996 ↗
29. Cell death induced in a murine mastocytoma by 42–47 C heating in vitro: evidence that the form of death changes from apoptosis to necrosis above a critical heat load10.1080/09553009014552221 ↗
30. The role of intracellular oxidation in death induction (apoptosis and necrosis) in human promonocytic cells treated with stress inducers (cadmium, heat, X-rays)10.1078/0171-9335-00159 ↗
31. Cellular responses to hyperthermia (40–46 C): cell killing and molecular events10.1080/02656730701769841 ↗
32. Tumor ablation: common modalities and general practices10.1053/j.tvir.2013.08.002 ↗
33. The cellular and molecular basis of hyperthermia10.1016/S1040-8428(01)00179-2 ↗
34. Magnetic graphene-based nanotheranostic agent for dual-modality mapping guided photothermal therapy in regional lymph nodal metastasis of pancreatic cancer10.1016/j.biomaterials.2014.07.064 ↗
35. Heat shock proteins as regulators of the immune response10.1016/S0140-6736(03)14075-5 ↗
36. Stressed apoptotic tumor cells stimulate dendritic cells and induce specific cytotoxic T cells10.1182/blood-2002-05-1389 ↗
37. Elucidating the fundamental mechanisms of cell death triggered by photothermal therapy10.1021/acsnano.5b00021 ↗
38. How dying cells alert the immune system to danger10.1038/nri2215 ↗
39. The apoptosome: signalling platform of cell death10.1038/nrm2153 ↗
40. Dissecting the molecular mechanism of apoptosis during photothermal therapy using gold nanoprisms10.1021/nn505468v ↗
41. Current approaches for combination therapy of cancer: the role of immunogenic cell death10.3390/cancers12041047 ↗
42. Decoding cell death signals in inflammation and immunity10.1016/j.cell.2010.02.015 ↗
43. Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells10.1080/2162402X.2017.1311433 ↗
44. Engineering nanomedicines through boosting immunogenic cell death for improved cancer immunotherapy10.1038/s41401-020-0400-z ↗
45. Immunogenic cell death in cancer and infectious disease10.1038/nri.2016.107 ↗
46. Consensus guidelines for the definition, detection and interpretation of immunogenic cell death10.1136/jitc-2019-000337 ↗
47. Coordinating the mechanism of actions of ferroptosis and photothermal effect for cancer theranostics
48. Photothermal nanozyme-ignited Fenton reaction-independent ferroptosis for breast cancer therapy10.1016/j.jconrel.2021.09.019 ↗
49. A dual-mode nanoprobe for evaluation of the autophagy level affected by photothermal therapy10.1039/C9CC03319J ↗
50. Autophagy inhibition enabled efficient photothermal therapy at a mild temperature10.1016/j.biomaterials.2017.06.030 ↗
51. Library screening to identify highly-effective autophagy inhibitors for improving photothermal cancer therapy10.1021/acs.nanolett.1c02825 ↗
52. Hallmarks of cancer: the next generation10.1016/j.cell.2011.02.013 ↗
53. Immunosuppressive lymphatics10.1038/s41568-018-0091-7 ↗
54. Tumor microenvironment: a metabolic player that shapes the immune response10.3390/ijms21010157 ↗
55. Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy10.1038/s41467-019-12771-9 ↗
56. Radiation and heat improve the delivery and efficacy of nanotherapeutics by modulating intratumoral fluid dynamics10.1021/acsnano.7b06301 ↗
57. Photothermal therapy promotes tumor infiltration and antitumor activity of CAR T cells10.1002/adma.201900192 ↗
58. Nanoengineered CAR-T biohybrids for solid tumor immunotherapy with microenvironment photothermal-remodeling strategy10.1002/smll.202007494 ↗
59. Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control10.1038/s41551-021-00781-2 ↗
60. Coating biomimetic nanoparticles with chimeric antigen receptor T cell-membrane provides high specificity for hepatocellular carcinoma photothermal therapy treatment10.7150/thno.40291 ↗
61. Smoldering and polarized inflammation in the initiation and promotion of malignant disease10.1016/j.ccr.2005.02.013 ↗
62. Nanoengineering of nanorattles for tumor treatment by CT imaging-guided simultaneous enhanced microwave thermal therapy and managing inflammation10.1016/j.biomaterials.2018.06.041 ↗
63. Hyperthermia in combined treatment of cancer10.1016/S1470-2045(02)00818-5 ↗
64. Deep local hyperthermia for cancer therapy: external electromagnetic and ultrasound techniques
65. Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorods10.1021/ja057254a ↗
66. Nanoparticles for photothermal therapies10.1039/C4NR00708E ↗
67. Heating efficiency of multi-walled carbon nanotubes in the first and second biological windows10.1039/c3nr01398g ↗
68. Gold nanoparticles in biological optical imaging10.1016/j.nantod.2018.12.006 ↗
69. Gold nanoparticle-based paper sensor for simultaneous detection of 11 benzimidazoles by one monoclonal antibody10.1002/smll.201701782 ↗
70. Gold nanomaterial engineering for macrophage-mediated inflammation and tumor treatment10.1002/adhm.202000818 ↗
71. An enzyme-free electrochemical biosensor based on well monodisperse Au nanorods for ultra-sensitive detection of telomerase activity10.1016/j.bios.2019.111834 ↗
72. Bi2S3 coated Au nanorods for enhanced photodynamic and photothermal antibacterial activities under NIR light10.1016/j.cej.2020.125488 ↗
73. BSA-bioinspired gold nanorods loaded with immunoadjuvant for the treatment of melanoma by combined photothermal therapy and immunotherapy10.1039/C8NR05323E ↗
74. Platinum (II) drug-loaded gold nanoshells for chemo-photothermal therapy in colorectal cancer10.1021/acsami.9b18855 ↗
75. PEGylated thermosensitive lipid-coated hollow gold nanoshells for effective combinational chemo-photothermal therapy of pancreatic cancer10.1016/j.colsurfb.2017.09.010 ↗
76. Laser-triggered small interfering RNA releasing gold nanoshells against heat shock protein for sensitized photothermal therapy10.1002/advs.201600327 ↗
77. Concurrent photothermal therapy and photodynamic therapy for cutaneous squamous cell carcinoma by gold nanoclusters under a single NIR laser irradiation10.1039/C9TB01573F ↗
78. Gold nanoclusters modified mesoporous silica coated gold nanorods: enhanced photothermal properties and fluorescence imaging10.1016/j.jphotobiol.2020.112111 ↗
79. Phospholipid micelle-based magneto-plasmonic nanoformulation for magnetic field-directed, imaging-guided photo-induced cancer therapy10.1016/j.nano.2013.05.012 ↗
80. Gold nanoframeworks with mesopores for Raman–photoacoustic imaging and photo-chemo tumor therapy in the second near-infrared biowindow10.1002/adfm.201908825 ↗
81. Plasmonic gold nanoparticles: optical manipulation, imaging, drug delivery and therapy10.1016/j.jconrel.2019.08.032 ↗
82. Smart gold nanostructures for light mediated cancer theranostics: combining optical diagnostics with photothermal therapy10.1002/advs.201903441 ↗
83. Development of theranostic dual-layered Au-liposome for effective tumor targeting and photothermal therapy
84. Polydopamine-coated Au-Ag nanoparticle-guided photothermal colorectal cancer therapy through multiple cell death pathways10.1016/j.actbio.2018.10.032 ↗
85. Copper sulfide nanoparticles for photothermal ablation of tumor cells10.2217/nnm.10.85 ↗
86. Metallic 1T phase enabling MoS2 nanodots as an efficient agent for photoacoustic imaging guided photothermal therapy in the near-infrared-II window10.1002/smll.202004173 ↗
87. Carbon dot/WS2 heterojunctions for NIR-II enhanced photothermal therapy of osteosarcoma and bone regeneration10.1016/j.cej.2019.123102 ↗
88. Two-dimensional TiS 2 nanosheets for in vivo photoacoustic imaging and photothermal cancer therapy10.1039/C5NR00893J ↗
89. Morphology-controlled synthesis of molybdenum oxide with tunable plasmon absorption for phothermal therapy of cancer10.1002/cnma.202000311 ↗
90. Ultrathin PEGylated W18O49 nanowires as a new 980 nm-laser-driven photothermal agent for efficient ablation of cancer cells in vivo10.1002/adma.201204616 ↗
91. Photothermal therapy by using titanium oxide nanoparticles10.1007/s12274-016-1019-8 ↗
92. Nuclear-targeted photothermal therapy prevents cancer recurrence with near-infrared triggered copper sulfide nanoparticles10.1021/acsnano.7b06870 ↗
93. A chelator-free multifunctional [64Cu] CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy10.1021/ja106855m ↗
94. Biocompatible PEGylated MoS2 nanosheets: controllable bottom-up synthesis and highly efficient photothermal regression of tumor10.1016/j.biomaterials.2014.11.009 ↗
95. Layered MoS2 nanosheets modified by biomimetic phospholipids: enhanced stability and its synergistic treatment of cancer with chemo-photothermal therapy10.1016/j.colsurfb.2019.110631 ↗
96. Theranostic 2D ultrathin MnO2 nanosheets with fast responsibility to endogenous tumor microenvironment and exogenous NIR irradiation10.1016/j.biomaterials.2017.11.015 ↗
97. Surface modified Ti3C2 MXene nanosheets for tumor targeting photothermal/photodynamic/chemo synergistic therapy10.1021/acsami.7b13421 ↗
98. Coordination-induced exfoliation to monolayer Bi-anchored MnB2 nanosheets for multimodal imaging-guided photothermal therapy of cancer10.7150/thno.39715 ↗
99. High-throughput synthesis of single-layer MoS2 nanosheets as a near-infrared photothermal-triggered drug delivery for effective cancer therapy10.1021/nn501647j ↗
100. Preparation of ultrathin two-dimensional TixTa1− xSyOz nanosheets as highly efficient photothermal agents10.1002/anie.201703597 ↗