Kinetic evaluation and study of gold-based nanoparticles and multi-walled carbon nanotubes as an alkaline phosphatase inhibitor in serum and pure form
Source abstract
Abstract
In this study, gold nanoparticles (AuNPs) were synthesised using green chemistry to decorate multi-walled carbon nanotubes (MWCNTs) made from walnut shells transmission electron microscopy, field-emission scanning electron microscopy (FESEM), atomic force microscopy and fourier transforms infrared spectroscopy were used to diagnose MWCNTs and AuNPs. MWCNT-COOAu, MWCNT-COO and MWCNT-Au were diagnosed by Raman, energy dispersive X-ray analysis and FESEM. The effect of AuNPs, MWCNT-COO, MWCNT-COOAu and MWCNT-Au on pure and serum alkaline phosphatase (ALP) enzyme activity was studied in vitro using the enzyme-substrate 4-nitrophenyl disodium orthophosphate. For pure enzymes, Vmax slightly increased as the concentration of MWCNT-Au, MWCNT-COOAu and MWCNTCOO increased, whereas the Vmax values decreased as the concentration of AuNPs increased. The inhibition type for all NPs varied. For serum ALP enzyme, the Vmax values for Au-based NPs decreased as the concentration of NPs increased. The Vmax values exceeded the standard value at the concentrations of 25, 50 and 75 ppm for MWCNT-Au and MWCNT-COOAu, whereas the Vmax values increased over the standard value for all concentrations of AuNPs.
Source: expertdata · Quality: candidate unverified · Source record ↗
Research context
OpenAlex topics: Alkaline Phosphatase Research Studies · Selenium in Biological Systems · Medical and Biological Ozone Research
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
References (47)
Show source-provided references
1. Parivar K, Fard FM, Bayat M, Alavian SM, Motavaf M (2016) Evaluation of iron oxide nanoparticles toxicity on liver cells of BALB/c rats, Iran. Red Crescent Med J 18(1)10.5812/ircmj.28939 ↗
2. Tang D, Cui Y, Chen G (2013) Nanoparticle-based immunoassays in the biomedical field. Analyst 138(4):981–99010.1039/c2an36500f ↗
3. Silva AC et al (2011) Application of hyperthermia induced by superparamagnetic iron oxide nanoparticles in glioma treatment. Int J Nanomed 6:591
4. Xu C et al (2011) Nanoparticle-based monitoring of cell therapy. Nanotechnology 22(49):494001
5. Wang Z-Y, Wang L, Zhang J, Li Y-T, Zhang D (2011) A study on the preparation and characterization of plasmid DNA and drug-containing magnetic nanoliposomes for the treatment of tumors. Int J Nanomed 6:871
6. Marchesan S, Kostarelos K, Bianco A, Prato M (2015) The winding road for carbon nanotubes in nanomedicine. Mater Today 18(1):12–1910.1016/j.mattod.2014.07.009 ↗
7. Sanginario A, Miccoli B, Demarchi D (2017) Carbon nanotubes as an effective opportunity for cancer diagnosis and treatment. Biosensors 7(1):910.3390/bios7010009 ↗
8. Lim E-K, Kim T, Paik S, Haam S, Huh Y-M, Lee K (2015) Nanomaterials for theranostics: recent advances and future challenges. Chem Rev 115(1):327–39410.1021/cr300213b ↗
9. Mendes RM, Silva GAB, Caliari MV, Silva EE, Ladeira LO, Ferreira AJ (2010) Effects of single wall carbon nanotubes and its functionalization with sodium hyaluronate on bone repair. Life Sci 87(7–8):215–22210.1016/j.lfs.2010.06.010 ↗
10. Lobo AO et al (2010) An evaluation of cell proliferation and adhesion on vertically-aligned multi-walled carbon nanotube films. Carbon N Y 48(1):245–25410.1016/j.carbon.2009.09.012 ↗
11. Dykman LA, Khlebtsov NG (2011) Gold nanoparticles in biology and medicine: recent advances and prospects. Acta Nat (aнглoязычнaя вepcия) 3(2):34–55
12. Loeb LA, Monnat RJ (2008) DNA polymerases and human disease. Nat Rev Genet 9(8):594–60410.1038/nrg2345 ↗
13. Allocati N, Masulli M, Di Ilio C, Federici L (2018) Glutathione transferases: substrates, inhibitors and pro-drugs in cancer and neurodegenerative diseases. Oncogenesis 7(1):1–1510.1038/s41389-017-0025-3 ↗
14. Roake CM, Artandi SE (2020) Regulation of human telomerase in homeostasis and disease. Nat Rev Mol cell Biol 21(7):384–39710.1038/s41580-020-0234-z ↗
15. Benn CL, Dawson LA (2020) Clinically precedented protein kinases: rationale for their use in neurodegenerative disease. Front Aging Neurosci 12:24210.3389/fnagi.2020.00242 ↗
16. López-Otín C, Bond JS (2008) Proteases: multifunctional enzymes in life and disease. J Biol Chem 283(45):30433–3043710.1074/jbc.R800035200 ↗
17. den Hertog J (2003) Regulation of protein phosphatases in disease and behaviour: meeting on protein phosphatases. EMBO Rep 4(11):1027–103110.1038/sj.embor.7400009 ↗
18. Balbaied T, Moore E (2019) Overview of optical and electrochemical alkaline phosphatase (ALP) biosensors: recent approaches in cells culture techniques. Biosensors 9(3):10210.3390/bios9030102 ↗
19. Sharma U, Pal D, Prasad R (2014) Alkaline phosphatase: an overview. Indian J Clin Biochem 29(3):269–27810.1007/s12291-013-0408-y ↗
20. Guo J et al (2018) An allosteric-probe for detection of alkaline phosphatase activity and its application in immunoassay. Front Chem 6:61810.3389/fchem.2018.00618 ↗
21. Gilboa T, Ogata AF, Walt DR (2022) Single molecule enzymology for diagnostics: profiling alkaline phosphatase activity in clinical samples. ChemBioChem 23(1):e20210035810.1002/cbic.202100358 ↗
22. Fernandez NJ, Kidney BA (2007) Alkaline phosphatase: beyond the liver. Vet Clin Pathol 36(3):223–23310.1111/j.1939-165X.2007.tb00216.x ↗
23. Levitt MD, Hapak SM, Levitt DG (2022) Alkaline phosphatase pathophysiology with emphasis on the seldom-discussed role of defective elimination in unexplained elevations of serum ALP—a case report and literature review. Clin Exp Gastroenterol 15:4110.2147/CEG.S345531 ↗
24. Atheer DM (2021) Synthesis of new imidazoline dervatives and evaluating of their biochemical effect on hepatitis C patients. Mustansiriyah
25. Sanfins E, Augustsson C, Dahlback B, Linse S, Cedervall T (2014) Size-dependent effects of nanoparticles on enzymes in the blood coagulation cascade. Nano Lett 14(8):4736–474410.1021/nl501863u ↗
26. Mohammed AM, Al-Khateeb IK, Haider AJ, Rahim RA, Hashim U (2017) Preparation of DNA biosensor application from fuel oil waste by functionalization and characterization of MWCNT. Sens Bio-sens Res 16:1–510.1016/j.sbsr.2017.09.002 ↗
27. Chinh VD, Speranza G, Migliaresi C, Van Chuc N, Tan VM, Phuong N-T (2019) Synthesis of gold nanoparticles decorated with multiwalled carbon nanotubes (Au-MWCNTs) via cysteaminium chloride functionalization. Sci Rep 9(1):1–910.1038/s41598-018-37186-2 ↗
28. Shabestarian H et al (2016) Green synthesis of gold nanoparticles using sumac aqueous extract and their antioxidant activity. Mater Res 20:264–27010.1590/1980-5373-mr-2015-0694 ↗
29. He X, Xu X, Bo G, Yan Y (2020) Studies on the effects of different multiwalled carbon nanotube functionalization techniques on the properties of bio-based hybrid non-isocyanate polyurethane. RSC Adv 10(4):2180–219010.1039/C9RA08695A ↗
30. Behnam MA et al (2018) Novel combination of silver nanoparticles and carbon nanotubes for plasmonic photo thermal therapy in melanoma cancer model. Adv Pharm Bull 8(1):4910.15171/apb.2018.006 ↗
31. Naief MF, Khalaf YH, Mohammed AM (2022) Novel photothermal therapy using multi-walled carbon nanotubes and platinum nanocomposite for human prostate cancer PC3 cell line. J Organomet Chem 975:12242210.1016/j.jorganchem.2022.122422 ↗
32. Mohammed SN, Mohammed AM, Al-Rawi KF (2022) Novel combination of multi-walled carbon nanotubes and gold nanocomposite for photothermal therapy in human breast cancer model. Steroids 186:109091
33. Ghudhaib KK, Ibrahim LM, Al-Rubaee EA, Salman ZA (2016) Determination of Vmax and Km of ALP, AST and peroxidase in saliva of chronic periodontitis patients with and without ZnO NPs: a kinetic study. Int J Adv Res Biol Sci 3(7):85–91
34. Abjameh R, Moradi O, Amani J (2014) The study of synthesis and functionalized single-walled carbon nanotubes with amide group. Int Nano Lett 4(2):9710.1007/s40089-014-0097-4 ↗
35. Haniyeh F, Abdollah A, Abolghasem D (2013) Controlled growth of well-Aligned carbon nanotubes, electrochemical modification and electrodeposition of multiple shapes of gold nanostructures. Mater Sci Appl 2013
36. Derakhshan MS, Moradi O (2014) The study of thermodynamics and kinetics methyl orange and malachite green by SWCNTs, SWCNT-COOH and SWCNT-NH2 as adsorbents from aqueous solution. J Ind Eng Chem 20(5):3186–319410.1016/j.jiec.2013.11.064 ↗
37. Mo Y, Tang Y, Wang S, Lin J, Zhang H, Luo D (2015) Green synthesis of silver nanoparticles using eucalyptus leaf extract. Mater Lett 144:165–16710.1016/j.matlet.2015.01.004 ↗
38. Prakash P, Gnanaprakasam P, Emmanuel R, Arokiyaraj S, Saravanan M (2013) Green synthesis of silver nanoparticles from leaf extract of Mimusops elengi, Linn. for enhanced antibacterial activity against multi drug resistant clinical isolates. Colloids Surf B Biointerfaces 108:255–25910.1016/j.colsurfb.2013.03.017 ↗
39. Basavegowda N, Idhayadhulla A, Lee YR (2014) Phyto-synthesis of gold nanoparticles using fruit extract of Hovenia dulcis and their biological activities. Ind Crops Prod 52:745–75110.1016/j.indcrop.2013.12.006 ↗
40. Ferrari AC, Robertson J (2000) Interpretation of Raman spectra of disordered and amorphous carbon. Phys Rev B 61(20):1409510.1103/PhysRevB.61.14095 ↗
41. Georgakilas V, Kordatos K, Prato M, Guldi DM, Holzinger M, Hirsch A (2002) Organic functionalization of carbon nanotubes. J Am Chem Soc 124(5):760–76110.1021/ja016954m ↗
42. Auvray S, Derycke V, Goffman M, Filoramo A, Jost O, Bourgoin J-P (2005) Chemical optimization of self-assembled carbon nanotube transistors. Nano Lett 5(3):451–45510.1021/nl048032y ↗
43. Datsyuk V et al (2008) Chemical oxidation of multiwalled carbon nanotubes. Carbon N Y 46(6):833–84010.1016/j.carbon.2008.02.012 ↗
44. Kim SJ et al (2007) Defect-induced loading of Pt nanoparticles on carbon nanotubes. Appl Phys Lett 90(2):2311410.1063/1.2430993 ↗
45. Nelson DL, Lehninger AL, Cox MM (2008) Lehninger principles of biochemistry. Macmillan, New York
46. Li K, Wang J, He Y, Cui G, Abdulrazaq MA, Yan Y (2018) Enhancing enzyme activity and enantioselectivity of Burkholderia cepacia lipase via immobilization on melamine glutaraldehyde dendrimer modified magnetic nanoparticles. Chem Eng J 351:258–26810.1016/j.cej.2018.06.086 ↗
47. Huang Y, Jiang J, Wang Y, Chen J, Xi J (2021) Nanozymes as enzyme inhibitors. Int J Nanomed 16:114310.2147/IJN.S294871 ↗