journal article·2026-07

The strategy and research progress of MOFs-derived nanozymes

Junlin Li, Wei Zhang, Zhen Huang, Shengjie Ma, Yingfei Hu, Xiangqian Yin, Jianwei Wang, Dingsheng Wang

Carbon· Volume 258
Publisher page

Abstract

No abstract is available for this record. The assistant can identify its topic from the title, but cannot infer the study’s results.

Source: Not provided · Quality: missing

Research context

OpenAlex topics: Advanced Nanomaterials in Catalysis · Metal-Organic Frameworks: Synthesis and Applications · Nanocluster Synthesis and Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

References (100+)

Show source-provided references
1. MOF nanozymes: active sites and sensing applications10.1039/D4QI02555E ↗
2. Enzyme and nanozyme biosensors based on MOFs for pesticide detection10.1016/j.trac.2025.118381 ↗
3. Two birds, one stone: smart MOF nanozymes for dual catalysis and theranostics10.1002/smll.202509992 ↗
4. Recent progress of metal-organic framework-based nanozymes with oxidoreductase-like activity10.1039/D3AN01995K ↗
5. Recent progress in MOFs-based nanozymes for biosensing10.1007/s12274-023-5770-3 ↗
6. Metal-organic framework based nanozymes: promising materials for biochemical analysis10.1039/D0CC04890A ↗
7. Exploring single-atom nanozymes toward environmental pollutants: monitoring and control10.1007/s40820-025-01734-z ↗
8. The cooperative effects of the Rh-M dual-metal atomic pairs in formic acid oxidation
9. Insights on catalytic mechanism of CeO2 as multiple nanozymes10.1007/s12274-022-4666-y ↗
10. Single-atom nanozymes towards central nervous system diseases10.1007/s12274-022-5104-x ↗
11. Tailoring metal-organic frameworks-based nanozymes for bacterial theranostics10.1016/j.biomaterials.2021.120951 ↗
12. Recent advances in the construction and analytical applications of metal-organic frameworks-based nanozymes10.1016/j.trac.2018.06.001 ↗
13. MOF catalysis meets biochemistry: molecular insights from the hydrolytic activity of MOFs towards biomolecules10.1039/D2ME00213B ↗
14. Activity regulation and applications of metal–organic framework‐based nanozymes10.1007/s12598-023-02311-2 ↗
15. Recent advances in nanozyme sensors based on metal-organic frameworks and covalent-organic frameworks10.3390/bios14110520 ↗
16. Advancing stroke therapy: the potential of MOF-based nanozymes in biomedical applications
17. A series of MOF/Ce-based nanozymes with dual enzyme-like activity disrupting biofilms and hindering recolonization of bacteria10.1016/j.biomaterials.2019.04.007 ↗
18. Single‐atom materials: the application in energy conversion
19. Chiral supramolecular nanomaterials: from chirality transfer and amplification to regulation and applications
20. Excellent laccase-like activity of melamine modified Cu-NH2-BDC and selective sensing analyses toward phenols and amines10.1007/s12274-024-6888-7 ↗
21. Nano-enhanced Fenton/Fenton-like chemistry: integrating peroxidase nanozymes, MOFs, and MXenes for next-generation colorimetric biosensors10.1039/D5NA00387C ↗
22. Nanozymes in biomedical applications: innovations originated from metal-organic frameworks
23. Recent progress in the design fabrication of metal-organic frameworks-based nanozymes and their applications to sensing and cancer therapy10.1016/j.bios.2019.04.061 ↗
24. Ultrasound-triggered piezocatalytic MOF(Hf)-Pt nanozymes for efficient ROS scavenging in the treatment of osteoarthritis10.1016/j.cej.2025.167229 ↗
25. Emerging single-atom nanozymes for catalytic biomedical uses10.1007/s12274-023-5864-y ↗
26. Hollow Mn/Co-MOF as a powerful oxidase-like nanozyme for detection of total antioxidant capacity and black tea fermentation degree
27. Enhanced peroxidase-like activity of MOF nanozymes by co-catalysis for colorimetric detection of cholesterol10.1039/D3TB00958K ↗
28. UiO-66 MOF nanozymes as affinity columns for proteomics applications10.1021/acsanm.4c07008 ↗
29. Metal-organic framework (MOF) hybridized gold nanoparticles as a bifunctional nanozyme for glucose sensing10.1039/D3SC02598E ↗
30. In situ fabrication of ultrasmall gold Nanoparticles/2D MOFs hybrid as nanozyme for antibacterial therapy
31. Colorimetric and SERS dual-mode detection of GSH in human serum based on AuNPs@Cu-porphyrin MOF nanozyme10.1016/j.aca.2024.342552 ↗
32. Engineering platelet membrane-coated bimetallic MOFs as biodegradable nanozymes for efficient antibacterial therapy
33. Competition and synergistic effects of Ru-based single-atom and cluster catalysts in electrocatalytic reactions10.1007/s40843-023-2776-5 ↗
34. Bioinspired metal-organic framework nanozyme reinforced with thermosensitive hydrogel for regulating inflammatory responses in Parkinson's disease10.1007/s12274-023-6304-8 ↗
35. A facile strategy to construct MOF-based nanocatalyst with enhanced activity and selectivity in oxytetracycline degradation10.1007/s12274-024-6558-9 ↗
36. A trifunctional surface ligand-directed general synthesis of 2D MOF hybrid nanozymes for customizable applications10.1016/j.jcis.2025.137453 ↗
37. Core@Shell MnO2@MOF nanozymes with accelerated oxygen generation for synergistic chemodynamic and starvation therapy10.1021/acsanm.5c02222 ↗
38. Single-atom nanozymes: from bench to bedside10.1007/s12274-022-5060-5 ↗
39. Direct optical visualization of in situ photodegradation dynamics in metal-organic frameworks10.1021/cbmi.5c00047 ↗
40. Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes10.1039/c3cs35486e ↗
41. Single-atom nanozyme enabled fast and highly sensitive colorimetric detection of Cr(VI)10.1016/j.jhazmat.2020.124898 ↗
42. Polypyrrole‐boosted photothermal energy storage in MOF‐based phase change materials
43. Atomically dispersed hierarchically ordered porous Fe-N-C single-atom nanozymes for dyes degradation10.1007/s12274-023-5847-z ↗
44. Cascade reaction system integrating single-atom nanozymes with abundant Cu sites for enhanced biosensing10.1021/acs.analchem.9b05437 ↗
45. Silicon dioxide-protection boosting the peroxidase-like activity of Fe single-atom catalyst for combining chemo-photothermal therapy10.1007/s12274-024-6495-7 ↗
46. Honeycomb-like mesoporous Fe-N-C single-atom nanozyme with excellent POD-like activity: preparation, properties, and application as a sensor array for discrimination of phenolic acids10.1016/j.talanta.2026.129364 ↗
47. Single-atom Co-N-C nanozymes with excellent oxidase-like activity for colorimetric detection of l-cysteine10.1016/j.saa.2025.125778 ↗
48. Metal-organic framework (MOF)-derived flower-like Ni-MOF@NiV-layered double hydroxides as peroxidase mimetics for colorimetric detection of hydroquinone10.1016/j.aca.2023.341959 ↗
49. Photothermal‐Amplified single atom nanozyme for biofouling control in seawater
50. Dual vacancies‐engineered two‐dimensional sonocatalysts for ultrasound‐augmented and PANoptosis‐Driven catalytic tumor nanotherapy
51. Optimizing hydrazine activation on dual‐site co‐zn catalysts for direct hydrazine‐hydrogen peroxide fuel cells
52. Oxygen vacancy-rich amorphous MOF/graphene nanozymes with self-sustaining catalytic circuits for drug-resistant infection wound healing10.1002/adhm.202503227 ↗
53. A peroxidase-like single-atom Fe-N5 active site for effective killing human lung adenocarcinoma cells10.1007/s12274-022-5127-3 ↗
54. Multifunctional Ce-MOF@PdNPs with colorimetric fluorescent electrochemical activity for ultrasensitive and accurate detection of diethylstilbestrol10.1007/s12274-024-6951-4 ↗
55. Pyrolysis-free and universal synthesis of metal-NC single-atom nanozymes with dual catalytic sites for cytoprotection10.1016/j.carbon.2022.09.034 ↗
56. Coordination engineering in fe‐mn dual‐atom nanozyme: yielding ROS storm to efficiently promote wound healing
57. Homogeneous colorimetric-fluorescent dual-mode detection of thiamethoxam and clothianidin via carbon dot-mediated single-atom nanozyme inhibition and inner filter effect10.1016/j.foodcont.2025.111913 ↗
58. Electrochemical immunosensor utilizing Zn-Fe-N-C single-atom nanozyme and Ti3C2Tx@Au for ultrasensitive detection of cytokeratins21-110.1016/j.microc.2025.112810 ↗
59. Facilely fabricating triple-atom Fe/Zn/Ir luminescent nanozymes with peroxidase-like activity for dual mode melatonin detection10.1016/j.cej.2024.152663 ↗
60. High entropy metal organic framework nanozyme with cocktail effect for efficient extraction and colorimetric detection of tetracycline in food and water environment10.1016/j.foodchem.2025.146148 ↗
61. Unprecedented peroxidase-mimicking activity of single-atom nanozyme with atomically dispersed Fe-Nx moieties hosted by MOF derived porous carbon10.1016/j.bios.2019.111495 ↗
62. Single-atomic iron doped carbon dots with both photoluminescence and oxidase-like activity
63. CoSe2 hollow microspheres with superior oxidase-like activity for ultrasensitive colorimetric biosensing10.1016/j.talanta.2020.121009 ↗
64. An ultrathin and crack‐free metal‐organic framework film for effective polysulfide inhibition in lithium–sulfur batteries
65. CeO2/C nanowire derived from a cerium(III) based organic framework as a peroxidase mimic for colorimetric sensing of hydrogen peroxide and for enzymatic sensing of glucose10.1007/s00604-019-4032-2 ↗
66. Preparation of amorphous MOF based biomimetic nanozyme with high laccase- and catecholase-like activity for the degradation and detection of phenolic compounds10.1016/j.cej.2022.134677 ↗
67. 3D printing MOF nanozyme hydrogel with dual enzymatic activities and visualized glucose monitoring for diabetic wound healing10.1016/j.cej.2023.144649 ↗
68. Two-dimensional iron MOF nanosheet as a highly efficient nanozyme for glucose biosensing10.1039/D0TB01598A ↗
69. NIR plasmonic nanozymes: synergistic enhancement mechanism and multi-modal anti-infection applications of MXene/MOFs
70. Fusing bacteriophage specificity with MOF nanozyme catalysis to construct an AI-enhanced platform for simultaneous pathogen detection and eradication10.1016/j.cej.2025.170578 ↗
71. Nanozyme decorated metal-organic frameworks for enhanced photodynamic therapy10.1021/acsnano.7b07746 ↗
72. Novel ZIF-67-derived Co3O4 hollow nanocages as efficient nanozymes with intrinsic dual enzyme-mimicking activities for colorimetric sensing10.1007/s00604-025-07112-1 ↗
73. Multifunctional Sr/Se co-doped ZIF-8 nanozyme for chemo/chemodynamic synergistic tumor therapy via apoptosis and ferroptosis10.7150/thno.92663 ↗
74. MOF-derived N-doped porous carbon with active magnesium sites as an efficient oxidase mimic for biosensing10.1016/j.snb.2022.132409 ↗
75. Using Cu-Based metal-organic framework as a comprehensive and powerful antioxidant nanozyme for efficient Osteoarthritis treatment
76. Se‐containing MOF coated dual‐Fe‐atom nanozymes with multi‐enzyme Cascade activities protect against cerebral ischemic reperfusion injury10.1002/adfm.202204025 ↗
77. Signal “off-on” electrochemical aptamer sensing of interleukin-6 based on platinum nanoparticles/MIL-88B MOF nanozyme10.1016/j.talo.2025.100524 ↗
78. Biomimic nanozymes with tunable peroxidase-like activity based on the confinement effect of metal-organic frameworks (MOFs) for biosensing10.1021/acs.analchem.2c00058 ↗
79. Ce-Based MOF nanozyme with oxidase-like activity for sensitive colorimetric detection of glutathione in periodontitis10.1016/j.colsurfa.2025.138333 ↗
80. In situ electrospinning MOF-Derived highly dispersed alpha-Cobalt confined in nitrogen-doped carbon nanofibers nanozyme for biomolecule monitoring10.1021/acs.analchem.3c05053 ↗
81. 1D/1D assembly of Co-capped N-doped CNT-MOF-derived/g-C3N4 micro tube as nanozyme-based colorimetric epinephrine detector10.1016/j.jallcom.2025.184666 ↗
82. Iron-nitrogen co-doped hollow porous carbon spheres for sensitive colorimetric sensing of alkaline phosphatase in complex biological samples10.1016/j.microc.2025.114580 ↗
83. Biomimetic engineering of a neuroinflammation-targeted MOF nanozyme scaffolded with photo-trigger released CO for the treatment of Alzheimer's disease10.1039/D4SC02598A ↗
84. Enhanced multienzyme catalytic activity of Mn MOF induced by bioligands for efficient tumor therapy10.1186/s12951-025-03694-3 ↗
85. Bimetallic MOF-derived colorimetric CRISPR/Cas-aptasensor for the detection of sulfadimethoxine utilizing reversible change of peroxidase-mimicking activity of ZrFe MOF nanozymes10.1016/j.microc.2025.113580 ↗
86. An Au bipyramids@CuZn MOF core-shell nanozyme enables universal SERS and a colorimetric dual-model bioassay10.1039/D4CC01602E ↗
87. Antibacterial therapy: in situ fabrication of ultrasmall gold Nanoparticles/2D MOFs hybrid as nanozyme for antibacterial therapy
88. Self-enhanced peroxidase-like activity in a wide pH range enabled by heterostructured Au/MOF nanozymes for multiple ascorbic acid-related bioenzyme analyses10.1039/D3AN00017F ↗
89. Efficient biocatalytic system for biosensing by combining metal-organic framework (MOF)-based nanozymes and G-Quadruplex (G4)-DNAzymes10.1021/acs.analchem.2c00600 ↗
90. Architectural design and electrochemical performance of MOF‐based solid‐state electrolytes for high‐performance secondary batteries
91. Geometric and defects engineering collaboration for enhanced cascade enzymatic nanoreactors10.1007/s12274-023-6119-7 ↗
92. Anthracene-based fluorescent MOFs decorated by platinum nanozymes as a multifunctional nanoplatform for enhanced photodynamic therapy and self-monitoring of real-time singlet oxygen10.1016/j.cej.2022.137333 ↗
93. Antimicrobial packaging films based on MOF nanozymes engineered via biomineralization and bimetallic hybridization for fruit preservation10.1016/j.foodchem.2025.144324 ↗
94. Enhancing the peroxidase-like activity of MoS2-based nanozymes by introducing attapulgite for antibacterial application and sensitive detection of glutathione10.1007/s12274-024-6685-3 ↗
95. Doping-engineered CuBDC MOF nanozymes for sensitive tannic acid detection and antioxidant discrimination10.1016/j.saa.2025.127382 ↗
96. Electrochemical biosensor for ultrasensitive exosomal miRNA analysis by cascade primer exchange reaction and MOF@Pt@MOF nanozyme10.1016/j.bios.2020.112554 ↗
97. Nanozymes for nanohealthcare10.1038/s43586-024-00315-5 ↗
98. Mn-Ce-MOF derived multivalent Mn/Ce oxides: excellent oxidase-like activity and smart sensing for AA10.1016/j.apsusc.2025.165376 ↗
99. Metal-organic frameworks-derived bimetallic oxide composite nanozyme fiber membrane and the application to colorimetric detection of phenol10.1016/j.colsurfa.2022.129662 ↗
100. A metal-organic framework-derived ruthenium-nitrogen-carbon nanozyme for versatile hydrogen sulfide and cystathionine gamma-lyase activity assay10.1016/j.bios.2023.115785 ↗