journal article·2021Open access

Calcium Silicate Nanowires Based Composite Electrospun Scaffolds: Preparation, Ion Release and Cytocompatibility

Feng BAO, Jiang CHANG

Journal of Inorganic Materials· Volume 36· Issue 11

Abstract

Electrospun scaffolds have been widely used in tissue engineering, particularly, bioceramics such as calcium silicate (CSH) composite electrospun scaffolds have shown excellent bioactivity by releasing SiO 3 2-ions during the degradation of calcium silicate in composite electrospun scaffolds, which are bioactive in stimulating angiogenesis. However, the effective ion concentration is in a narrow range from 0.79 to 1.8 g/mL. Therefore, it is of great significance for tissue engineering applications to accurately control the ion release concentration of the calcium silicate composite scaffolds, so that the ions released from materials can remain in the effective concentration range for a long time. In this study, we prepared a variety of scaffolds with calcium silicate composite electrospun by adjusting pore size of electrospun scaffolds and controlling the location of calcium silicate nanowires inside the scaffolds, and
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Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Conducting polymers and applications · Advanced biosensing and bioanalysis techniques

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