Development and characterization of cotton, organic cotton flat knit fabrics coated with chitosan, sodium alginate, calcium alginate polymers, and antibiotic drugs for wound healing

This article deals with development and characterization of cotton and organic cotton flat knit bandages for wound healing. Bioploymers such as chitosan–sodium alginate, sodium–calcium alginate, and their mixtures were coated on the bandage and subjected to Fourier transform–infrared and scanning electron microscope analysis. Bacteria present in infected wound samples were identified using different bio-chemical methods. Three antibiotic drugs were selected based on the antibiotic sensitivity test and incorporated into the polymer-coated samples to improve the antibacterial and wound healing properties. Further, the antibacterial activities of the samples were evaluated against the identified bacteria in the wound for about 4 days. The strongest antibacterial activity was found in chitosan–sodium alginate–calcium alginate coated with chloramphenicol and tetracycline hydrochloride drug-loaded cotton and organic cotton samples. Hence, these bandages are suitable for quick wound healing process.